致病性

①Location of WD gene in Ch inese: Using pairwise linkage analysis and multipoint linkage analysis method, w e constructed a genetic map of DNA markers within D13q14.2-3 which refined the location of WD gene by restriction fragment length polymorphism and microsatellite polymorphism analysis;②Screen for mutations of WD gene in Chinese people: we detected the structure of 21 exons of WD ge ne in 45 patients from 39 pedigrees by PCR-SSCP(Single strand conformation poly morphism) and PCR-DNA sequencing technology, found a new mutation in exon 5 and nuclcotide sequence analysis showed it is a T insertion. We also conformed the Arg778Leu in exon 8, the highest frequence mutation point in Chinese people, wit h mutation rate 22.8%in total;③Carrier detection and presymptomatic diagnosi s of WD: Based on DNA recombination technology, we peformed successfully the gen e diagnosis in all individuals of 79 families with WD and built up a helpful spe cific enzyme cut method (PCR-Msp1) to detect the carrier and presympomatic patients in Chinese pe ople with WD.

①WD的基因定位研究：通过RFLP及微卫星多态性分析，应用两位点及多位点连锁软件，建立了中国人WD基因在D13q14.2-3区域的精细遗传连锁图谱，从而首次对中国人WD基因进行了精确定位；②WD基因突变研究：应用PCR-SSCP及DNA测序技术，对39个家系45名WD患者进行该致病基因的21个外显子突变筛选，发现WD基因5号外显子存在新的T插入突变，并证实中国人WD基因的突变热点为8号外显子，突变形式为Arg778Leu，其频率为22.8%；③WD的症状前诊断和杂合子检出：应用DNA重组技术对79个家系进行基因诊断，成功地进行了WD的症状前诊断和杂合子检出，并建立了WD的基因筛选的PCR-Msp 1酶切方法。

Chemotaxis may play an important role at the early stages in pathogenesis of phytopathogenic bacteria.

进一步说明趋化性可能在植物病原细菌致病的早期起重要作用。

We hypothesised that Candida colonisation promotes food allergy, which is known to contribute to a pathogenic response in atopic dermatitis.

我们假设念珠菌定植可促进食物的致敏作用，这一作用导致特应性皮炎的致病反应。

The process flow of frozen boiled crawfish ,the genera of microorganism and its heat resistance and pathogenicity were analyzed in this article.

分析了出口冻煮小龙虾的生产工艺、控制微生物的种类及其相应的耐热性和致病隐患等方面，得出蒸煮是控制小龙虾生产加工过程中微生物的有效方法，并且得出影响蒸煮的因素有蒸煮数量、加工季节和虾体大小。

Some virulent crown gall strains AT(subscript 1-1), AT(subscript 1-3), AT(subscript 2-7), AT(subscript 2-8), AT(subscript 2-11), AT(subscript 2-12) are selected by the infection experiment on the carrot fragments.

胡萝卜接种试验初步选出致病力强的菌株AT(下标 1-1)、AT(下标 1-3)、AT(下标 2-7)、AT(下标 2-8)、AT(下标 2-11)、AT(下标 2-12)将菌株AT(下标 2-7)、AT(下标 2-8)、AT(下标 2-11)、AT(下标 2-12)接种于塑料大棚盆栽的山桃、毛桃、甘肃桃，进行桃砧木感病性评价试验。

The pathogenic mechanism of toxin from Phoma herbarum to dayflower was studied through measuring cell membrane permeability, MDA content and activities of CAT, POD and APX. The result indicated that toxin increased permeability of cell membrane.

以草茎点霉毒素对鸭跖草叶片组织细胞膜透性、丙二醛含量、过氧化氢酶、过氧化物酶以及抗坏血酸过氧化物酶活性的影响，研究草茎点霉毒素对鸭跖草的致病机理。

This paper not only introduce mainly disserve, physiological races、filtrate resist disease data、mechanism of resist disease and pathological changes、prevention and cure synthetically and so on, but also advance some suggest of writer.

通过对1990~2000年这5种病害的危害情况、生理小种鉴定、抗病资源筛选、品种抗病机制及病菌致病机制、综合防治等方面研究进展的综述，笔者从宏观角度提出了一些建议性的观点。

Pseudomonas aeruginosa can produce a variety of toxin,and Pseudomonas aeruginosa exotoxin Ais a lethal exotoxin and the most important pathogenic factor.There is some research on the structure and mechanism of PEA.

绿脓杆菌能产生多种与毒力有关的物质，其中绿脓杆菌外毒素A(Pseudomonas aeruginosa exotoxin A，PEA)是一种致死性外毒素，是绿脓杆菌最主要的致病因子。

There were two obvious peaks of cotton Fusarium wilt in xinjiang.

另外，发病与降雨、品种抗病性、菌系的致病力强弱、田间菌量的多少等也密切相关。

But the disease occurs only in those who have two copies of the gene for the disease-causing haemoglobin.

但这种镰状细胞性贫血症只会发生在同时有两组这种致病的血红蛋白的人身上。

Do you know, i need you to come back

你知道吗，我需要你回来

Yang yinshu、Wang xiangsheng、Li decang,The first discovery of haemaphysalis conicinna.

1〕 杨银书，王祥生，李德昌。安徽省首次发现嗜群血蜱。