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The three isolates have four specific replacements in 87 , 88 , 95 , and 119 in S1 hypervariable region, and a unique cleavage site R-X-R-T-G-R in 3' terminal region. These data may be valuable for investigation of molecular basis of the serotyping, tissue tropism and pathogenicity of these virus isolates.

本文的3个分离毒株Q1、J2和T3在S1高变区的87,88,95和119有4个特有的替换,在3'末端有独特的裂解位点R-X5-R-T-G-R,这些结果可能对这些分离毒株的血清型特异序列和组织趋向性和致病性的分子决定区方面的研究有重要的价值。

The three isolates have four specific replacements in 87, 88, 95, and 119 in SI hypervariable region, and a unique cleavage site R-X-R-T-G-R in 3 terminal region. These data may be valuable for investigation of molecular basis of the serotyping, tissue tropism and pathogenicity of these virus isolates.

由于SI蛋白序列99-12川立氨基酸之间的序列可能对病毒的致病性起重要作用,SI蛋白5,高变区(56-69;117-131)与中和表位和血清型密切相关,这些区域在IBV血清型和基因型间起联系作用。

The results of this study confirm the instability of prophage, and suggested that the prophage plays important role in the pathogenicity of O157:H7, and in the evolution of pathogenic bacteria.

该研究证实了编码Stx的原噬菌体具有不稳定性,原噬菌体对O157的致病性具有重要作用,也提示原噬菌体在致病菌的进化过程中也具有重要作用。

Members individual from family 1 and 2 were found to carry the same pathological mutations as in their proband but without clinical symptoms. They were identified as preclinical patients.

其中家系1和家系2中分别发现1名成员与先证者存在相同位点的NOTCH3基因致病性突变,尚未出现与先证者相应的临床表现,被确定为临床前期患者。

There are nine fimbiral operons identified in the genome of Klebsiella pneumoniae NTUH-K2044, a highly invasive strain isolated from Taiwan university hospital, by the HMMER search.

利用生物资讯分析方法HMMER,我们在一株从台湾大学附设医院的病患身上所分离出具有高致病性的NTUH-K0244菌株的基因体中找到九套线毛基因组。

There were many heterobacteria aid vibrios but few Vibrio parahaemolyticus in living bait. The correlation coefficients between larvae and heterobacteria and vibrios in water were 0.704 and 0.840 in culture system respectively, while the correlation among heterobacteria, vibrios in living bait and larvae, oater were weak or negative.

活饵中异养菌和弧菌数量很大,致病性副溶血弧菌量很低养殖体系中幼体与水体中的异养菌和弧菌的相关系数分别为0.704和0.840;活饵中异养菌、弧菌与对虾幼体和养殖水体相关性很低或呈负相关。

Among parasite s, protozoa are usually more pathogenic than nematodes.

在寄生虫中,原虫的致病性往往比线虫的要高。

Among parasites, protozoa are usually more pathogenic than nematodes.

在寄生虫中,原虫的致病性往往比线虫的要高。

Null mutant Δmnh6 produced appeared offwhite hyphae, showed reduction in growth, conidiation and appressorium formation, and also showed reduction in appressorium turgor pressure. And the hyphae were more readily wettable by a solution containing SDS and EDTA and more easily digested by fungal cell-wall-digesting enzymes. The appressoria produced by Δmnh6 mutants showed diminished host penetration and the infectious hyphae of Δmnh6 mutants showed reduced in planta growth. Targeted deletion of mnh6 resulted in the greatly reduced virulence capacity to barley and rice CO39 in infection assays.

突变子Δmnh6的菌落形态不同于野生型GUY11,菌落呈灰白色,菌丝稀疏,生长速度变慢,产孢菌丝细胞壁的溶剂疏水性消失,菌丝细胞壁容易被细胞壁降解酶降解,产孢减少,孢子形态变得细长,孢子的附着胞形成率降低,附着胞的膨压降低,附着胞对寄主植物表面的穿透能力减弱,侵入后生长速度减慢,喷雾接种后对大麦和水稻CO39的致病性消失。mnh6基因重新引入Δmnh6后,突变子的表型恢复。

Several hrp mutants, which losted their ability to trigger hypersensitive response on nonhost plant tobacco and to be pathogenic on rice, were produced from Xanthomonas oryzae pv.oryzicolaby chenmical mutagenesis.

化学诱变水稻条斑病细菌(Xanthomonas oryzae pv.oryzicola,Xooc),获得了在水稻上丧失致病性和在非寄主烟草上丧失激发过敏反应的hrp基因突变体。

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