致病性

Nowadays, research on the interrupt genes of such slow-growth mutants is seldom, either does not the research on the relationship between pathogenicity and hypha development.

目前，菌落生长缓慢突变体的研究和该类突变体相关基因的报道较少，菌丝生长与致病性的关系的研究也不系统。

Ascites syndromes disease is a common and ubiquitous disease in the industrial culture with turbot, which often results in turbot's massive mortalities. In June 2006, an outbreak of ascites syndromes disease of the cultured turbot Scophthalmus maximus occurred in an indoor farm in Shandong Province of China Through the isolation, purification as well as cultivation of the bacteria in the diseased fish, and by tracing the bacteria in the well water, rearing pond water along with the feeding trash fish, it was found that the bacterium RF-1 which existed in the trash fish was similar to the bacterium FS-1 in the diseased turbot; artificial infection test demonstrated that the bacteria RF-1 and FS-1 had the same infection symptoms for healthy turbots.

腹水病是工厂化养殖大菱鲆的一种常见病和多发病，常造成鱼类大规模的死亡。2006年6月山东某大菱鲆Scophthalmus maximus养殖场发生大规模腹水病，通过对病鱼细菌的分离、纯化和培养，对养殖井水、养殖池水和所用饵料小杂鱼进行细菌追踪调查，将从该养殖场所用小杂鱼中分离得到的细菌RF-1与鱼体分离的细菌FS-1进行比较，并对其进行人工感染试验，结果证明这2株菌对健康大菱鲆都具有很强的致病性，而且感染症状完全一致。

Ascites syndromes disease is a common and ubiquitous disease in the industrial culture with turbot, which often results in trubot's massive mortalities. In June 2006, an outbreak of ascites syndromes disease of the cultured turbot Scophthalmus maximus occurred in an indoor farm in Shandong Province of China. Through the isolation, purification as well as cultivation of the bacteria in the diseased fish, and by tracing the bacteria in the well water, rearing pond water along with the feeding raw fish, it was found that the bacterium RF-1 which existed in the trash fish was similar to the bacterium FS-1 in the diseased turbot; artificial infection test demonstrated that the bacteria RF-1 and FS-1 had the same infection symptoms for healthy turbots.

腹水病是工厂化养殖大菱鲆的一种常见病和多发病，常造成鱼类大规模的死亡。2006年6月山东某大菱鲆 Scophthalmus maximus 养殖场发生大规模腹水病，通过对病鱼细菌分离、纯化和培养，对养殖井水、养殖池水和所用饵料小杂鱼进行细菌追踪调查，将从该养殖场所用小杂鱼中分离得到的细菌RF-1与鱼体分离的细菌FS-1进行比较，并对其进行人工感染试验，结果证明这2株菌对健康大菱鲆都具有很强的致病性，而且感染症状完全一致。

OBJECTIVE To study the infectivity of the Vibrio parahaernolyticus isolated from the brine.

目的 研究从海水中分离出的副溶血弧菌的致病性。

Objective To understand the infectivity and pathogenicity of the plasma of hepatitis E virus viremia to primate animals.

目的 了解戊型肝炎病毒核酸阳性血浆对灵长类动物的感染性和致病性。

Function of A-Rich region in DNAβ associated with Tomato yellow leaf curl China virus.

项目的完成可望为防范粉虱传双生病毒病在我国的突发性流行和发掘新的病害控制策略提供科学依据；同时，可望使我国在双生病毒DNA 分子互作及致病性相关基因功能研究等方面跻身国际。

The results showed that when the proportion of the resistant subpopulation within the h-VRSA was low, te level of the toxic factor and its pathogenicity to animals had no difference from that of the standard strain. If proportion of the resistant subpopulation increased the level of coagulase and lecithinase changing from positive from negative and the ring of hemolysis disappeared. The speed of proliferation of the organisms in the animal slowed down and the LD50 increased.

结果 当试验菌株中耐药亚群的比例较少时，其毒力因子及动物致病性检测结果与金葡菌标准菌株无显著差异；随着试验菌株中耐药亚群的比例增加，表现为血浆凝固酶、卵磷脂酶由阳性转为阴性，血琼脂平板上溶血环消失，细菌在动物体内增殖速度减慢，对动物的半数致死量(LD50)增加。

The liqase was positively controlled by HAI and AI-2 to some extent. The lecithinase was negatively controlled by HAI-1, and the hemolysin was negatively controlled by both HAI-1 and AI-2. Special primers of luxS gene were designed from the luxS gene sequence of V. harveyi obtained from the GenBank, and the gene was amplified from a pathogenic strain V. harveyi VIB645 by PCR. The luxS gene was cloned to a cloning vector pUC, and was sequenced. It was found that the open reading frame is 519 bp. The similarity of the luxS gene from V. harveyi VIB645 to the published sequence of V. harveyi strain in GenBank was only 90%.

从GenBank中获取哈维氏弧菌中编码AI-2合成酶的luxS基因序列设计一对特异性引物从哈维氏弧菌VIB645中PCR扩增luxS基因，将luxS基因克隆于pUC载体并测序，发现其与GenBank中已发表的哈维氏弧菌的luxS基因序列相似性为90%，证明LuxS/AI-2系统在哈维氏弧菌不同的菌株中的具有一定的特异性，推测LuxS/AI-2系统可能与哈维氏弧菌的致病性或发光现象有关。

The result is identical basally with past one about pathogenicity mensuration.

该分类结果与以往的致病性测定小种划分基本一致。

When I trained as a microbiologist around the year 2000, the focus was still on pathogenic bacteria.

在年-2000附近，当我训练了作为微生物学家，焦点仍然在致病性细菌。

Do you know, i need you to come back

你知道吗，我需要你回来

Yang yinshu、Wang xiangsheng、Li decang,The first discovery of haemaphysalis conicinna.

1〕 杨银书，王祥生，李德昌。安徽省首次发现嗜群血蜱。