致病

P210bcr/abl plays a central role in the pathophysiology of CML. The purpose of this study was to construct a cell line model that bcr/abl expression can be regulated by Tetoff inducingexpressionsystem. The fulllength b3a2 bcr/abl cDNA was subcloned into the pTRE2hyg expression vector to construct the pT2P210 plasmid.

CML是目前致病分子信号基础研究最为清楚的肿瘤之一，1960年Nowell和Hungerford在CML患者的白血病细胞中发现Ph染色体［1］，1973年Rowley等［2］进一步应用染色体分带技术证明，Ph染色体是由9q34的abl基因和22q11 的 bcr 基因相互易位形成的 bcr/abl 融合基因。

Peripheral nerve injury induced by mechanical trauma, ischemia, metabolic abnormality or local inflammation can lead to chronic pain symptoms, including hyperalgesia, allodynia, spontaneous pain and paraesthesia.

机械性外伤、缺血、机体代谢异常以及局部炎症等各种致病因素可直接或间接引起外周神经的损伤，诱发以痛觉过敏、痛性感觉异常、自发性疼痛及感觉倒错为主要表现的持久异常痛感觉，称之为慢性痛。

Objective To construct the eukaryotic expression vector for pathogenic gene MYOC of primary open angle glaucoma and express in COS-7 cells.

目的 构建原发性开角型青光眼致病基因MYOC的真核表达质粒，并在COS-7细胞中表达MYOC蛋白。

It found that the vast majority of both smokers and nonsmokers were aware that second-hand smoke is harmful to children.

大约95%的不吸烟者和84%的吸烟者都同意&婴幼儿吸入父母的二手烟可能致病&的论断。

No month plague, SARS, polio, people infected with highly pathogenic avian influenza, dengue fever, anthrax, diphtheria, neonatal tetanus, leprosy, typhus, kala-azar, echinococcosis and wire Disease cases reported.

当月无鼠疫、传染性非典型肺炎、脊髓灰质炎、人感染高致病性禽流感、登革热、炭疽、白喉、新生儿破伤风、麻风病、斑疹伤寒、黑热病、包虫病和丝虫病病例报告。

Studying the risk factor and pathogenesis of cerebral infarction can prevent its occurrence , and find a new method for the preventions and cures of this disease.

研究导致脑梗死的危险因素及其致病机制可预防脑梗死的发生，为疾病的防治开辟了新的途径。

The study found that baboons, monkeys zanthopygia Ukraine and the African green monkey, and other specific primates, but will not carry HIV disease.

研究发现，狒狒、乌白眉猴和非洲绿猴等特定灵长类动物，都携带艾滋病病毒却不会致病。

The study found that baboons, monkeys zanthopygia Ukraine and the African green monkey, and other specific primates carry these viruses are not pathogenic.

研究发现，狒狒、乌白眉猴和非洲绿猴等特定灵长类动物携带这些病毒却不会致病。

Aeromonas hydrophila is a Gram-negative bacterium that is pathogenic in fish, causing motile aeromonad septicaemia. It has been speculated that A.

致病性嗜水气单胞菌(Aeromonas hydrophila，Ah)是我国淡水养殖鱼类的重要病原对其侵袭机制和毒力因子的研究有重要的意义。

These suppressors were previously identified as pathogenicity determinates, indicating that there is ongoing coevolution of plant defense and viral offense.

这些镇压以前确定为致病determinates ，显示仍有持续进化的植物防御和病毒进攻。

Do you know, i need you to come back

你知道吗，我需要你回来

Yang yinshu、Wang xiangsheng、Li decang,The first discovery of haemaphysalis conicinna.

1〕 杨银书，王祥生，李德昌。安徽省首次发现嗜群血蜱。