致病

To verify pathopoiesis of PRKAG2 with a novel missense mutation G100S responsible for Chinese PRKAG2 cardiac syndrome and promote pathogenic investigation of the PRKAG2 gene,we study the functional consequences of the mutation in the level of the cell and molecule by overexpressing mutants of PRKAG2 in CCL13 cells.

为了验证PRKAG2 G100S新突变在中国人PRKAG2心脏综合征家系中的致病作用，深入认识PRKAG2 G100S错义突变引起的功能变化，推动PRKAG2基因的致病机制研究，我们通过在CCL13细胞中过表达突变基因，从细胞、分子水平研究了PRKAG2 G100S突变的生物学功能。

The phytotoxin can pathogenesis not only to Yunnan pine, but also to Shimao pine, P. kesiya var. langbianensis and Huasan pine, P. armandi.

该毒素不仅对寄主云南松产生致病作用，而且对思茅松(P.kesiya var.langbianensis)和华山松同样具有致病作用。

This project studied the mechanism of a newfound phytotoxin from Alternaria alternata Keissler that infects Crofton weed. According with the result from experiment, the project group drew a conclusion that the toxin did not inhibit respiration in mitochondrion, so the key problem was whether the toxin inhibited photosynthesis in chloroplast.

本项目重点研究新近分离纯化的紫茎泽兰致病型链格孢菌毒素的致病机理，项目组依据实验结果排除了毒素抑制线粒体呼吸作用的可能性，把重点放在毒素对叶绿体光合作用的影响上。

The basic principles are the same, that is, to p revent the spread and cause the destruction of pathogenic microorganisms.

它们的基本原理是相同的，也就是要防止致病微生物的传播和消灭致病微生物。

Spinocerebellar ataxias are a clinically and genetically heterogeneous group of neurodegenerative disorders.

第一部分 SCA家系致病基因定位第一章一个新的SCA家系致病基因定位脊髓小脑型共济失调(spinocerebellar ataxias，SCA)是一种具有高度临床和遗传异质性的神经系统退行性疾病，多呈常染色体显性遗传。

The vacuolated effect of HP, which wa s a pathogeny found recently, was different from the effects of HP measured eve r.

结果 HP的这种空泡毒作用不同于已知的HP的致病因素，而是一种新近发现的致病因素。

The aim of the present study was to learn the manifestation of which the patients mainly complained of dry mouth, the corresponding pathogenic factors and their correlation, which is helpful to build up a thinking pattern for diagnosis and therapy based on the different clinical manifestations of patients with xerostomia.

本实验试图通过了解口腔门诊以口干为主诉患者的临床表现类型；口干患者的主要致病因素；并寻找口干相关因素与其临床表现类型之间的联系，以期初步建立根据口干患者不同临床表征作出致病因素分析和进行针对性治疗的临床思维模式，并为进一步的分析性研究及试验性研究提供线索。

Identification of extensive phenotypic information to 6 pare cultures and detection of the mol% G+C ratio of the DNA to representative strains, showed that the examined bacteria belonged to a new morphovar of Acinetobacter junii, and was designated as Acinetobacter junii Morphovar Ⅰ. In addition, serotype, antibiotic sensitivity and pathogenicity of isolates were studied, the results showed that the 6 strains have the same K-antigen and O-antigen, there arc no obvious differences in sensitivity and resistance to used 37 antimicrobial agents between strains, and have strong pathogenicity to experimental stone bonder and Bastard halibut.

经对6株纯培养菌在形态特征、理化特性等方面较系统的表观分类学指征鉴定及代表菌株DNA中G+C mol%的测定，表明为琼氏不动杆菌的一个新形态型并定名为琼氏不动杆菌形态型Ⅰ(Acinetobacter junii morphovar Ⅰ)；同时，对该菌进行了血清型、对抗菌类药物的敏感性及致病作用等方面的试验，初步表明此6株菌具有同种的表面及同种的菌体抗原，对供试37种抗菌类药物在不同菌株间的敏感及耐药无明显差异，对供试石鲽及牙鲆均具有较强的致病作用。

Swine enteropathogenic E. colis were rejuvenescenced and 6 of them were selected to prepare blood serum. We had tested the reactance of cross agglutination and agar diffusion between the strains and the blood serums. No. 300 and No. 343 were selected because they had highly cross reaction. To test superantigen of No.300 and No.343, the antigens made by both of them immunized piglets, and then we detected the serum 0D values with indirect ELISA. The OMP and PF of No. 300 and No. 343 were extracted for SDS—PAGE and westen-blotting.

本研究针对10株猪致病性大肠杆菌，经复壮后选取致病性强的6菌株作为供试菌株，制备免疫血清与这6菌株的多种抗原分别进行交叉凝集试验和琼脂扩散试验，根据各菌株抗原的交叉反应程度，筛选出抗原交叉程度高的菌株300和343，检测两菌株超抗原的毒性作用，以不同方式制备抗原免疫仔猪，用间接ELISA检测免疫效果，并提取菌株300和343的外膜蛋白和渗透因子经SDS—PAGE及免疫印迹试验，进行相关分析。

Some differences of pathogenicity of different cotton isolotes were observed on cotton seedlings, but not on cotton bolls.

来自棉花上的不同苎麻疫霉菌株对棉苗的致病力存在一定的差异，但对棉铃的致病力差异不明显。

Breath, muscle contraction of the buttocks; arch body, as far as possible to hold his head, right leg straight towards the ceiling (peg-leg knee in order to avoid muscle tension).

呼气，收缩臀部肌肉；拱起身体，尽量抬起头来，右腿伸直朝向天花板（膝微屈，以避免肌肉紧张）。

The cost of moving grain food products was unchanged from May, but year over year are up 8%.

粮食产品的运输费用与5月份相比没有变化，但却比去年同期高8％。