致病

According to the change of incidence of and mortality from disease tha modern society and life bring us, Introspect the cause of disease.

摘要根据现代社会和生活给人们带来的疾病发生变化的情况即发病率、致死率的改变，反思疾病的致病因素。

Different from the importation characteristic before 90s, strains after 90s were highly isogenous, suggested that the cholera epidemics in Sichuan province after 90s were endemic source. Inaba 1d strains from national wide epidemic in 2001 and 2002 were the same RT. Strains typed as different phagetypes (phagetype 6, phagetype 13 and phagetype 1) might be from a same clone.

除82-007、95-001外，所试菌株均具有致病性；20世纪90年代以四川省发生的霍乱为输入性，90年代后四川省流行的菌株高度同源，具有地方疫源性；2001、2002年在四川省乃至全国引起流行的稻叶1d为同 RT型，为传入性霍乱；噬菌体分型6型、13型菌株和1型菌株可能来自同一克隆系。

Different from the importation characteristic before 90s, strains after 90s were highly isogenous, suggested that the cholera epidemics in Sichuan province after 90s were endemic source. Inaba 1d strains from national wide epidemic in 2001 and 2002 were the same RT. Strains typed as different phagetypes (phagetype 6, phagetype 13 and phagetype 1) might be from a same clone.

除82-007、95-001外，所试菌株均具有致病性；20世纪90年代以前四川省发生的霍乱为输入性，90年代后四川省流行的菌株高度同源，具有地方疫源性；2001、2002年在四川省乃至全国引起大流行的稻叶1d为同一RT型，为传入性霍乱；噬菌体分型6型、13型菌株和1型菌株可能来自同一克隆系。

Stylosa, but the pathogenicity of P II -3 was stronger than that of P I -1. The host range of P I -1 and P II -3 were the same. Their hosts were special to a certain extent. Only some species of mangrove such as Kandelia candel and Sonneratia apetala could be infected.

结果表明，菌株 P I -1和 P II -3均能引起红海榄赤斑病发生，但菌株 P II -3致病力比 P I -1的稍强；二者的寄主范围一致，均具有一定的寄主专化性，只能侵染部分红树植物如秋茄和无瓣海桑。

Spinal Cord Injury is the injury of spinal cord structure and function caused by several different kinds of elements which incur the change of kinesalgia , sensation and autonomic nerves function below the injury level.

脊髓损伤(Spinal Cord Injury，SCI)是由于多种不同致病因素引起的脊髓结构、功能的损害，造成损伤水平以下正常运动、感觉、自主神经功能的改变。

The further study will identify the defected gene of the lamellar cataract, and make it possible for gene diagnosis and gene therapy.

进一步的研究工作将明确其致病基因，使该病的基因诊断和基因治疗成为可能。

ConclusionIt has first provided the evidences of CoolDry that injured the windpipe and skins and the defenced of "lanket of Cilla-mucus"and reduced the expression of bcl-2 gene, which was related to the mechanisms of CoolDry.

凉燥伤肺、伤津，致气道&纤毛-黏液毯&局部御邪屏障受损；肺津凝滞于肺，以致宣输失司则皮肤失养。本结果为凉燥致病提供实验资料。

ConclusionIt has first provided the evidences of Cool Dry that injured the windpipe and skins and the defenced of "lanket of Cilla-mucus"and reduced the expression of bcl-2 gene, which was related to the mechanisms of Cool Dry.

凉燥伤肺、伤津，致气道&纤毛-黏液毯&局部御邪屏障受损；肺津凝滞于肺，以致宣输失司则皮肤失养。本结果为凉燥致病提供实验资料。

The currently knowledge about pathogenic molecular mechanism of leptospira is not enough.

目前，对钩体的致病及免疫分子机理的认识不甚清楚。

Pathogenic Leptospira may evade innate immune response and spread in the body by resistance to killing by macrophages.

致病性钩体可以抵抗巨噬细胞的杀伤和降解，逃避固有免疫反应的清除作用，有利其在机体内播散。

This one mode pays close attention to network credence foundation of the businessman very much.

这一模式非常关注商人的网络信用基础。

Cell morphology of bacterial ghost of Pasteurella multocida was observed by scanning electron microscopy and inactivation ratio was estimated by CFU analysi.

扫描电镜观察多杀性巴氏杆菌细菌幽灵和菌落形成单位评价遗传灭活率。