致病

In this dissertation, firstly, the conditions of isolation and purification of specific toxin fractions produced by Exserohilum turcicum has been studied, and a high-efficient method has been established;secondly, the toxins were analysed by UV-Vis spectrophotometry;then the effect of specific toxin on death rate of corn leaves protoplast was studied by FDA as a tinct reagent;finally, using ANS as a probe and SDS-PAGE to study the membrane protein of the corn leaves with Htl gene. In a word, the aim of the research is to search some existent evidences of the toxin binding site on protoplasmic membrane, and provide proofs for nosogenesis of specific toxin in terms of cytology and the molecular biology.

本研究对玉米大斑病菌1号小种毒素的特异性组分进行分离，建立了高效的特异性毒素分离纯化方法，并对其进行了紫外波谱分析；用荧光素双醋酸酯染色法，测定了毒素特异性组分对原生质体死亡率的影响；进而用1-苯胺基-8-萘磺酸荧光探针标记法和SDS-PAGE电泳法对特异性毒素组分与Htl基因玉米细胞互作过程中的质膜蛋白进行了研究，旨在证明Htl基因玉米细胞质膜上存在特异性毒素组分结合蛋白，为从细胞和分子生物学角度阐明毒素的致病机理提供证据。

Here we report the result of the resistance of tobacco to Tobacco Mosaic Virus and micro-HR induced by AT-toxin.

摘 要：烟草赤星菌毒素是烟草赤星病菌产生的重要毒性因子，在病原菌致病过程中具有重要作用。

From an extensive molecular epidemiological surveillance around the H5N1 infected regions in the past several years, H5N1 viruses were isolated from the wild birds, eg. Bar-headed goose, brown-headed gull, great black-headed gull and common cormorant form Qinghai province and tree sparrow from henna province.

通过开展高致病性禽流感疫区的分子流行病调查，从野生鸟类分离到这种H5N1亚型的禽流感病毒，如从青海湖斑头雁、棕头鸥、渔鸥、鸬鹚，从河南的树麻雀等都分离到这种病毒。

To clone new disease gene of CMT, many myelin and myelin-related gene had been analysised by homologue searching. Quaking mouse, one of the mutation mouse with the clinic feature similar to Trembler mouse (the gene mutation mouse of PMP22) with the characterization of demylination in both the central and the peripheral nervous system, its disease gene had just been cloned accession No.

为进一步克隆新的CMT致病基因，在分析出CMT已克隆的基因均为与髓鞘有关的基因后，通过筛选有关髓鞘基因，我们发现，quaking基因突变小鼠因髓鞘形成障碍而出现震颤，其中枢和周围神经均有脱髓鞘，类似于PMP22基因突变鼠"Trembler"的临床表现。

The cervical vertebra gets sick the shoulder nerve trophopathy which creates also possibly is one kind of pathogenesis factor.

颈椎病所造成的肩部神经营养障碍也可能是一种致病因素。

Serious attention to the trypanosomes of mammals was drawn by the work of Timothy Lewis on the parasite of Indian rats, the importance of which was realized after Griffith Evans (1880) discovered the pathogenic trypanosome in horses and camels in India Trypanosoma evansi

Timothy Lewis对印度老鼠的寄生虫的研究引起了人们对于哺乳动物锥虫病的严重关注。Griffith Evans (1880)在印度发现马和骆驼身上的致病性锥虫之后，人们才认识到了哺乳动物锥虫病的重要性。

VAT ShTat1.1,ShTat1.2,ShTat1.3 and ShTat1.5were taken to study their growth characteristic,sensitivity to human serumand pathogenicity to mice.The result showed biological characteristic ofdifferent VAT were not all the same,which implied that antigenic variationof T.evansi was accompanied with variation of trypanosome otherphysiology and biochemistry property.

对伊氏锥虫安徽株单虫克隆ShTat1所产生的不同抗原变异体ShTat1.1、ShTat1.2、ShTat1.3和ShTat1.5的生长特征，对人血清敏感性以及对小鼠的致病力的比较研究发现，不同VAT的这些生物学特性不完全一致。

Objective: To study the prevalence and pathogenesis of TT virus in hemodialysis patients.

目的：研究血液透析患者中TT病毒的感染状况及其致病性。

Unfortunately the patient died after a sudden onset of ventricular fibrillation during an episode of pneumonia. We suggest that typhlitis may present as an initial manifestation of ALL and Giardia lamblia may play a role in its pathogenesis.

我们认为typhlitis可以成为急性淋巴球白血病之起始表现，且梨形鞭毛虫在其致病机转上可能扮演重要角色。

Ultramicroscopic infectious agent that replicates itself only within cells of living hosts; many are pathogenic.

超显微的有传染性的只有在活的宿主细胞内可以自我复制的个体，大多是致病的。

This one mode pays close attention to network credence foundation of the businessman very much.

这一模式非常关注商人的网络信用基础。

Cell morphology of bacterial ghost of Pasteurella multocida was observed by scanning electron microscopy and inactivation ratio was estimated by CFU analysi.

扫描电镜观察多杀性巴氏杆菌细菌幽灵和菌落形成单位评价遗传灭活率。