致病

Methods Peripheral blood samples were collected from the members in a family with autosomal dominant congenital sutural cataract.

目的 对我国一常染色体显性先天性缝合状白内障家系进行致病基因的定位。

The gene responsible for congenital sutural cataract in a Chinese pedigree is located at chromosome 3q21.1-q26.2 within a 38.6 cM region.

先天性缝合状白内障家系的致病基因位于3号染色体3q21.1-q26.2约38.6 cM区域内。

Context Multiple pathogenic mechanisms may be involved in generating the migraine symptom complex, and multimechanism-targeted therapy may confer advantages over monotherapy.

背景：偏头痛症候群的产生涉及到多个致病机制，因而，多机制的有目的的治疗方案可能比单一的治疗方案更具优势。

In order to further investigate the pathologic role of HOXD13 p.Q317R mutation during embryonic development and elucidate the molecular mechanism of typeⅤsyndactyly,we constructed mouse Hoxd13 Q50R replacement gene targeting vector,which will contribute to future generation of mouse model carrying the corresponding mutation.

为进一步研究HOXD13 p.Q317R突变体的功能及其导致V型并指的致病机制，我们成功构建了针对此点突变的小鼠Hoxd13 Q50R置换型基因打靶载体，为建立此点突变的小鼠模型奠定了基础。

There was big difference among the 22 different materials in the disease resistance. Translocation lines Pm97033 showed the highest resistance in reaction than others. The percentage of diseased root and severed level were 11.3% and 5.4%; substitution lines Wan7107 showed medium resistance to the fungus, the percentage of diseased root and severity level were 21.4% and 10.6%; F5 generation of common wheat with Till showed higher resistance to take-all fungus than the PS progenies of common wheat with Aegilops tauschii or the other common wheat varieties.

菌饼＋菌粒法对宁春4号的致病力明显高于菌饼法和菌粒法，其病根率、严重度和病茎率分别达到100.0%，57.3%和28.6%。22个遗传背景不同的小麦材料间抗病性差异较大，其中小麦－簇毛麦易位系Pm97033的抗病性最强，病根率和严重度分别为11.3%和5.4%；代换系Wan7107次之，病根率和严重度分别为21.4%和10.6%；硬粒小麦－簇毛麦双二倍体(TH1)与普通小麦品种杂交后代的抗病性强于粗山羊草与普通小麦品种杂交后代。

In order to demonstrate the taxonomic position of paramyxovirus Tianjin strain and explore its mechanism of pathogenesis.

为了进一步明确副粘病毒Tianjin株的来源和种系进化地位，探讨其高致病性的机制。

Through investigation and study of the leaf blight disease of Lycium in 5 different areas in Mongolia, the pathogen was identified in-house as Alternaria tenuis Nees, biological characteristics of the pathogens, the bioassay of toxins from A. tenuis Nees, the pathogenic mechanism of toxin and the toxicity determination of the fungicide were studied.

通过对内蒙古5个不同地区枸杞叶枯病的调查研究，确定其致病菌为细链格孢菌，并对该菌的生物学特性、病原菌毒素活性检测、毒素的致病机理及几种药剂的室内毒力进行了研究。

Objective: To establish and prepare hybridoma cell line secreting monoclonal antibody against tetanic toxoid, to develop a rapid assay for Tetanus and investigate the pathogenesis of the virus.

目的：制备并鉴定破伤风类毒素单克隆抗体杂交瘤细胞株，为破伤风的快速检测及致病机制的研究提供实验材料。

The origins of the more irulent strains of Toxoplasma were first documented in a 2001 Science paper from Boothroyd's group; the researchers found that the recombination of two relatiely benign strains of Toxoplasma can result in a thousand-fold increase in their ability to cause serious disease.

Boothroyd等人在2001年《科学》的文章中记载了弓形虫毒性菌株的来源，他们发现将两种相对良性的弓形虫菌株重组后，新菌株的致病性呈千倍上升。

Superficial thrombophlebitis must be considered as a risk factor of deep vein thromphlebitis are pain, reddening, swelling and induration.

浅表血栓性静脉炎被认为是深静脉血栓的危险致病因素，以疼痛、充血、水肿和硬化为特徵。

This one mode pays close attention to network credence foundation of the businessman very much.

这一模式非常关注商人的网络信用基础。

Cell morphology of bacterial ghost of Pasteurella multocida was observed by scanning electron microscopy and inactivation ratio was estimated by CFU analysi.

扫描电镜观察多杀性巴氏杆菌细菌幽灵和菌落形成单位评价遗传灭活率。