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Objective To investigate the effect of Jiuxiang Zhixie granule on vibrio parahaemolyticus activity and the small intestinal hyperfunction induced by neostigmine in mice.

目的 探讨九香止泻肠溶片对副溶血弧菌活性以及对新斯的明所致的小鼠小肠功能亢进的影响。

Results Tongxie Yaofang could inhibit gastrointestinal movement of diarrhea model and hyperfunction of small intestinal function in mice by neostigimine.

结果 痛泻要方对小鼠腹泻模型、新斯的明致小鼠小肠推进功能亢进均有一定抑制胃肠运动作用;对小鼠便秘模型、阿托品致小鼠小肠推进功能抑制均有一定促进胃肠运动作用;对正常小鼠及其小肠推进运动均无明显作用。

In the present study,in order to explore the roles of estrogen and progestin in epilepsy and elucidate their mechanisms of action, we utilized animal seizure models induced by intracerebroventricular coriaria lactone and intraperitoneal bemegride, studied the effects of estrogen and progestin on central nervous system functions in behavior,electrophysiological,cellular,molecular and gene levels by means of neuroelectrophysiology, flow cytometry, high performance liquid chromatography, immunocytochemical and in situ hybridization techniques.

为了探索雌、孕激素在癫痫发病中的作用,阐明其作用机制,本工作分别以马桑内酯侧脑室注射致痫、贝美格(Be腹腔注射致痫大鼠为实验对象,采用神经贫血电生理、流式细胞美白免疫荧光、高效液相色谱、美白免疫细胞化学、原位杂交早泻技术,从整体、行为、细胞、分子以及基因水平研究发现了雌、孕激素对大鼠中枢神经贫血系统功能的影响。

Epigastric fullness is the major syndrome that is fitted BD; it is caused by the disorder of stomach movement.

心下痞是半夏泻心汤证的主要证候。从现代医学角度看,心下痞是由胃运动障碍所致。

For long-term use of large dose,it still need further research such as the chronic toxicity tests 、 mutagenic tests (Ames test, micronuclei test and spermatozoon teratism test).Key words: Xin xiebai powder, acute respiratory distress syndrome, experimental study, therapeutic effects, Acute toxicity test

新泻白散的急性毒性实验证实了其安全性,但长期大剂量的使用,还有待于通过长期毒性实验、三致实验等毒理方法的进一步研究。

Apply the small intestinal movement experiments with charcoal powder in healthy mice,neostigmine―treated mice.

本实验采用番泻叶致腹泻法和小鼠小肠推进试验,新斯的明致小鼠小肠推进亢进试验对鼠掌老鹳草的抗腹泻药理作用进行研究。

And other species recorded in the pharmacopoeia through pharmacodynamic experiments. Method Adopt the method of rat diarrhea by senna. Apply the small intestinal movement experiments with charcoal powder in healthy mice,neostigmine―treated mice.

本实验采用番泻叶致腹泻法和小鼠小肠推进试验,新斯的明致小鼠小肠推进亢进试验对鼠掌老鹳草的抗腹泻药理作用进行研究。

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