致敏

The results indicate that the larger the concentration of chitosan in the capsules is the slower the release rate of capsule. The biocompatibility tests of the three heparin microcapcules/PLA composite materials show that all materials are negative and have no obvious toxicity. There is no potential hypersusceptibility substance in materials, and the content of pyrogen is conforming to the requirement of organisms.

三种微囊与PLA的复合材料经皮肤刺激试验、皮内刺激试验、热原试验、全身急性毒性试验和细胞培养试验，结果表明，所制备的复合材料在生物学评价试验中均呈阴性反应，材料无明显毒性，材料中不存在潜在致敏性物质，所含热原含量符合生物体的要求。

The products samples came from Guangdong Entomological Institute. The test was made according to the national standards of the People's Republic of China (GB 15670-1995) in Toxicological Test Methods of Pesticides for Registration. SPF SD mice were used to made the peroral toxicity test and percutaneous toxicity test. There were ten mice (including 5 female rice and 5 male rice) in each group. New Zealand rabbits were used to make the eye irritation test and skin irritation test, with 4 rabbits in each test. FMMU albino guinea pigs were used to make the hypersusceptibility test, with 13-20 guinea pigs in each group.

方法］产品样品来源于广东省昆虫研究所，根据中国人民共和国国家标准GB15670-1995《农药登记毒理学试验方法》进行试验，试验使用SPF级SD大鼠，用于经口、经皮毒性试验，每组10只，雌雄各半；新西兰白兔，用于眼刺激和皮肤刺激试验，每试验4只；FMMU白化豚鼠，用于致敏试验，每组13~20只。

The cell culture cytotoxicity,sensitization,intracutaneous injection were tested as well.

结果 ：加速储存前后样品红外光谱的各特征峰位置不变；理化性能波动不大；细胞毒性、皮肤致敏、皮内注射均符合相关标准要求。

Results Acute oral LD50 were 278 mg/kg and 56.2 mg/kg in rats and mice respectively, while dermal LD50＞2 000 mg/kg and inhalative LC50＞3 000 mg/m3. Skin and eye irritancy were estimated to be negative and mild respectively. Cumulative coefficient was 2.3 and allergic rate was 0%. A negative result was observed in Ames assay while increased frequencies of bone marrow micronuclei and spermatocyte chromosome aberrations were noted in the high dose (11.24 mg/kg) group.

结果 大小鼠急性LD50分别为278 mg/kg和56.2 mg/kg；大鼠经皮LD50＞2 000 mg/kg；急性吸入LC50＞3 000 mg/m3；无皮肤刺激性，轻度眼刺激性；蓄积系数2.3；致敏率为0；Ames试验结果阴性；微核和染色体在高剂量组(11.24 mg/kg)与阴性对照组相比有高度显著性差异(P＜0.01)；大鼠90天亚慢性经口的最大无作用剂量为2.825 mg/kg。

Objective To investigate the immune effects of Lactobacillus rhamnosus GG on immune response.

目的 探讨乳酸杆菌对空肠弯曲菌致敏的自身免疫病模型小鼠免疫功能的影响。

Objective To investigate the significance of human leukocyte antigen matching in highly sensitized recipients of renal transplantation.

目的 探讨人类白细胞抗原配型在高致敏受者肾脏移植中的临床意义。

Allergy were induced in all rats through intra-cutaneous injection of Freund's adjuvant (0.1 mL/rat)at metatarsus so as to establish multiple arthritis model in rat.

各组动物均在足跖部皮内注射完全弗氏佐剂(0.1 mL/只)致敏，以诱发多发关节炎。

The main mechanical factors included prosthetic materials, shapes and sizes, implant fixation methods, cl inical installation, interface micromotion, stress shielding, implant wear, interface integrity, and peri prosthetic high hydraulic pressure, etc.; the main biological factors included the types and sizes of wear particles, cell-activated responses, cytokine release, enzyme activation and allergic reactions to wear particles, etc..

机械学因素主要包括假体材料、形状和尺寸、假体固定方法、临床安装、界面微动、应力遮挡、假体磨损、界面密封程度、假体周围高液压等；生物学因素主要包括磨损颗粒种类和大小、细胞活化反应、细胞因子释放、酶类激活、对磨损颗粒的致敏反应等。

MATERIALS AND METHODS: RBC-C3bR, natural killer cell activity and T lymphocyte subsets of 53 patients with gastric cardia carcinoma, 51 gastric cancer and 30 healthy controls were measured by microzyme garland test, MTT-assay and monoclonal anti-human T lymphocyte antibody.

材料与方法：利用酵母菌花环试验、克隆抗体致敏花环法和MTT法对53例贲门癌、51例胃癌患者及30例正常人外周血RBC-3bR阳性率、T细胞CD3、CD4百分率、CD4/CD8比值及自然杀伤细胞活性进行测定。

Methods: Male Wistar rats were sensitized to ovalbumin and challenged with aerosol OVA.

应用OVA致敏的方法建立大鼠的哮喘模型。

This one mode pays close attention to network credence foundation of the businessman very much.

这一模式非常关注商人的网络信用基础。

Cell morphology of bacterial ghost of Pasteurella multocida was observed by scanning electron microscopy and inactivation ratio was estimated by CFU analysi.

扫描电镜观察多杀性巴氏杆菌细菌幽灵和菌落形成单位评价遗传灭活率。