致敏

Methods 24 SD rats were randomly divided into normal group,model group,aminophylline treatment group(35 mg/kg), 8 rats in each group. The bronchial asthma model in rats was built by egg protein sensibilization and longterm inhalation provocation. The rats in treatment group were lavaged each day from the first time of provocation.After 4week treatment, the rats were killed to obtain lung tissue for staining with HE.

24只SD大鼠随机分为正常组、模型组、治疗组，每组8只，除正常组外以卵蛋白致敏并吸入激发法制备大鼠哮喘模型，治疗组、模型组从第1次哮喘激发开始(造模第3周)分别给予氨茶碱、0.9%氯化钠溶液灌胃给药，1次/d，用药4周处死大鼠，取肺组织HE染色，用彩色图像分析仪测量支气管壁面积、支气管平滑肌面积，用ELISA双抗体夹心法测定肺组织MMP9和TIMP1含量。

The bronchial asthmatic model was established by egg protein sensibilization and longterm inhalation provocation.The rats of each treatment groups were lavaged each day from the first time of provocation to execution.After 4 weeks of treatment,the rats were killed to obtain lung tissue for dyeing of HE.A computer assisted image analysis system was used to determine the thickness change of bronchus wall and smooth muscle.The contents of MMP9 and TIMP1 in lung tissue were determined by ELISA double antibody sandwich method.

除正常组外以卵蛋白致敏并吸入激发法制备大鼠支气管哮喘模型，各治疗组均从第1次哮喘激发开始(造模第3周)至处死前每天灌胃给药，激发并给药4 w后处死大鼠，取肺组织HE染色，彩色图像分析仪测量支气管管壁厚度、平滑肌厚度，采用ELISA双抗体夹心法测定肺组织MMP9、TIMP1含量。

Results The Stemona sessilifolia cream had no acute toxicity,no cutaneous stimulation and no hypersensitive effects for the intact or damˉaged skin in rats,rabbits and guinnea pigs respectively.

结果 百部乳膏对大鼠完整皮肤及破损皮肤均无急性毒性反应，对白兔完整皮肤和破损皮肤无刺激性，对豚鼠完整皮肤无致敏作用。

Active MTrPs may serve as one of the sources of noxious input leading to the sensitization of spinal and supraspinal pain pathways in FMS.

活动MTrPs可作为一种有害刺激，致敏FMS中脊髓及脊髓上疼痛通路。

Methods: After the model of adjuvant arthritis was made in rat, tinospora hainanensis made from tinospora stem was injected into abdominal cavity of rats, then the changes of weight, circular diameter of ankle joint, time of thermalgesia, grades of the secondary arthritis and pathological influence were observed.

建立大鼠佐剂性关节炎模型，腹腔注射青牛胆茎水煎剂，观察其对佐剂性关节炎大鼠的体重、踝周径、热致敏时间、继发性关节炎评分、以及继发性关节炎关节病理的影响。

SP-R mRNA in nasal mucosa, obtained from two groups, were used to do reverse transcriptive polymerase chain reaction and Southern blot.

实验组用卵清蛋白行腹腔注射基础致敏，继之鼻局部激发建立大鼠变应性鼻炎模型。

Results Human complement can be activated by unsensitized EL-4 cell through the first pathway.

结果 未致敏EL-4细胞可直接以Ca2+、Mg2+离子依赖的第一途径活化人血清补体系统，在细胞数为1×104～2×104时，1：200稀释的人血清补体为EL-4细胞的非致死剂量。

Biopsy-proven acute rejection rates in the DSA and non-DSA were similar to the unsensitized group.

DSA和非DSA组间患者活检证实的急性排斥反应发生率均低于非致敏组。

objective in order to investigate the variety of the airborne fungi in jingzhou area and study the relationships between airborne fungi and allergic diseases.methods we surveyed the fungi sensitizing of air in jingzhou city from feb.1th,2007 to jau.31th,2008 to quantitatively observe the daily airborne fungi and count under microscope through one year.results the fungi spores were present through all year.more than 20 taxa of airborne fungi have been collected,among which the most common fungi were uredinales,ustilaginales,alternaria,etc.fungi spores were ralated with the season and weather,the most aboudant period in sring and summer.conclusion the airborne fungi were seen one year and were mostly allergenic.many of then had seasonal distribution.

目的：调查荆州市气传真菌的种类、数量变化及飘散规律，了解优势菌群与过敏性疾病的关系，为荆州市空气真菌过敏症的防治提供参考。方法：2007年2月1日至2008年1月31日，在荆州市设曝片点，每日换片，收集全年气传真菌样品，在显微镜下统计，定量获得每天及全年的真菌数量。结果：全年均可见真菌孢子，共收集真菌种类20多种，其中最常见的有链格孢、锈菌、黑粉菌等，其数量和季节、气候有关，以春季、夏季最多，秋季和冬季依次降低。结论：气传真菌全年均有分布并具有较强的致敏性，部分真菌具有明显的季节性变化。

The zoopery showed that percutaneous toxicity was low; score of skin irritation intensity was less than 5, without allergenicity; the effective rate on ulcer was 100% in clinical observation, healing rate in 4 weeks was 97.0%.

动物实验：其经皮毒性属低毒；皮肤刺激强度评分＜5分值；无致敏性；临床观察对溃疡创面治疗的有效率100%，4周愈合率为97.0%。

This one mode pays close attention to network credence foundation of the businessman very much.

这一模式非常关注商人的网络信用基础。

Cell morphology of bacterial ghost of Pasteurella multocida was observed by scanning electron microscopy and inactivation ratio was estimated by CFU analysi.

扫描电镜观察多杀性巴氏杆菌细菌幽灵和菌落形成单位评价遗传灭活率。