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In addition, CK/CH/LDL/97 I strain was attenuated by serial 115 passages in embryonated chicken eggs (note: the 115th passage were completed in our laboratory by prof. Rong Jun-gong).

同时将IBV CK/CH/LDL97Ⅰ/97株通过鸡胚连续传115代致弱成一株免疫原性良好的疫苗株(备注:F115的鸡胚传代由本实验室荣骏弓研究员完成)。

Objective: To observe the influence of ephedran on erythrocytolysin antibody formation of mouse caused by sheep erythrocyte and explore the effect of ephedran on the immune function of the mouse.

目的:观察麻黄多糖对绵羊红细胞所致小鼠溶血素生成的影响,以了解麻黄多糖对正常小鼠免疫功能的作用。

Abstract] Objective: To observe the influence of ephedran on erythrocytolysin antibody formation of mouse caused by sheep erythrocyte and explore the effect of ephedran on the immune function of the mouse.

目的:观察麻黄多糖对绵羊红细胞所致小鼠溶血素生成的影响,以了解麻黄多糖对正常小鼠免疫功能的作用。

Of them 25 cases of oral cancer (G1-2) were randomly divided into trail and control group . The remained 11 cases of nasopharyngeal and maxillary sinus cancer (NPC-MSC, mainly G3-4) were attributed to a third group (1st course: sBRM, then 2nd course: IAC). The order of drug-use of sBRM is: pre-immunomodulation of the reactivity of patient low-dose CTX and PolyI∶C, then in- juring tumor and thereby modulation of its immunogeneity (DDP-PYM regimen , thereafter, reaction enhancement modu- lation [low-dose rhuIL-2, Cimetidine and Indomethacin ] . All drugs, except for CTX, PolyI∶C and Indo, were fractionally delivered in a manner of continously infution in 8-10 hours via a retaining intra-external carotid artery catheter CAVAFIX 335 SPLITTOCAN G14, B.

将其中25例晚期口腔高、中分化鳞癌病人随机分为实验治疗(12例)和对照治疗(13例)两组,实验组采用sBRM疗法,具体用药为:先用小剂量环磷酰胺和聚肌胞对机体反应性作预调变,然后用低剂量DDP-PYM化疗杀伤&致创&癌细胞,使其免疫原性增强并借之诱导肿瘤浸润淋巴细胞,化疗结束后续用小剂量rhuIL-2激活和扩增TIL,特别是其中的T细胞,并借助小剂量西咪替丁、消炎痛调节机体以原发灶为中心的癌受创相关反应。

The sexual organ coefficents were calculated. Results: The high dose of osthole significantly increased the level of serum testosterone in the reproduction system disturbance mice and increased significantly the AR positive cells percentage of peritubular myoid cells. The low and high doses of osthole significantly increased the coefficients of seminal vesicle.

结果:蛇床子素高剂量可显著升高环磷酰胺致生殖系统损伤雄性小鼠血清中睾酮的含量(P.05),免疫组化结果显示,高剂量可增加睾丸肌样细胞AR阳性细胞表达百分率,高、低剂量可增加精液囊的脏器系数。

The intracellular expression of viral gene and phenotypical change of transformants were examined.

结果:分离获得了可长期体外培养的SV40转化细胞克隆,已传23代以上,体外存活超过250d;DNA印迹实验显示SV40大T基因已整合至细胞染色体内,间接免疫荧光检测示多数细胞胞核内有大T基因产物的表达;转化细胞对裸鼠无致瘤性,并可正常表达角蛋白。

It has been shown, however, that in terms of immune function, a transitional stage of dendritic cell maturation exists between immature myeloid dendritic cells and mature dendritic cells, which were named semimature dendritic cells.

新的研究发现一种半成熟树突状细胞亚群,其高表达主要组织相容性复合体Ⅱ、中等表达CD40、CD80和CD86等分子,在自身免疫性疾病中表现出诱导免疫耐受的潜能,其与未成熟树突状细胞一道被认为是致耐受细胞。

Bronchial asthma in acute episode model was established by a manner of egg albumen sensibilization and provocation. Rats in each group were treated by different drugs. Protein expressions of Fas/FaL-s in lung tissue were assayed by immune histochemistry.

以卵白蛋白致敏、激发的方式建立支气管哮喘急性发作期模型,各组分别给予相应治疗,免疫组化ABC法检测肺组织中Fas/FaL-s的蛋白表达。

Morphology of the EPCs was observed, and the growth curve of the EPCs was investigated. Surface antigens of the EPCs were analyzed by the flow-cytometer. The capability of intaking the acetylated low-density lipoprotein of the EPCs was detected using fluoresencent chemical method. The vasoformative capability and genetic stability of EPCs were cultured in matrigel, and examined by karyotype analysis.

观察培养细胞的形态,测定其生长动力学,采用流式细胞仪及免疫细胞化学方法检测其表型,应用细胞荧光化学法分析EPCs对乙酰化低密度脂蛋白(acetylated low-density lipoprotein, ac-LDL)的摄取功能,Matrigel上培养并检测其形成血管能力,染色体核型分析其遗传稳定性,裸鼠实验、软琼脂实验观察致瘤性。

Objective: To find out the major antigenic molecules of radiation-attenuated cercariae, and provide some useful candidate antigens for developing schistosomiasis vaccine.

目的:寻找照射致弱尾蚴中起免疫保护作用的抗原分子,为血吸虫病疫苗研究提供新的候选抗原。

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If you have any questions, you can contact me anytime.

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