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To observe pharmacological effects of Zangqingguo Houpian on antibacterial effect in vitro,2,4-dinitrophenol induced fever in rats,the croton oil induced swelling in mouse's ear and carrageen induced WBC movement in rat chest,rat granuloma induced by tampon,acetic-acid-induced twisting test in mouse and prednisolone acetate caused immunosuppressive mice.

采用体外抗菌、对2,4-二硝基苯酚所致大鼠发热、巴豆油所致小鼠耳肿胀及角叉菜胶致大鼠胸腔白细胞游走、棉球致大鼠肉芽组织增生、冰醋酸致小鼠疼痛、醋酸泼尼松龙致免疫低下等模型,观察藏青果喉片的药效学作用。

Objective To observe the effect of Monkshood acid polysaccharide on immunologic function in immunosuppressive mice.

目的 观察附子酸性多糖对环磷酰胺所致免疫低下小鼠免疫功能的影响。

The immune level tested in different time after injection with ginkgolic acids in sensitization mode showed that the expression of CD3〓 and CD4〓T lymphocytes increased, but CD8〓 was restrained, while the B lymphocytes was also increased. The results suggested that sensitivity was approved and T lymphocytes proliferation was induced, which strength cell immunity responsion, at the same time B lymphocytes was differentiated to IgE antibody-producing cells when contacted with ginkgolic acids as allergen.

大鼠经致敏方式接触银杏酸后,在不同时间的细胞免疫水平与体液免疫水平的研究结果表明,大鼠CD3〓及CD4〓T淋巴细胞的表达增加,而CD8〓T淋巴细胞的表达受到明显抑制,同时参与体液免疫的B淋巴细胞百分率呈增高趋势,提示银杏酸可能作为变应原使机体敏感性增强,诱导T细胞分裂增殖,增强细胞免疫应答,同时促进B细胞增殖分化成IgE抗体产生细胞。

OBJECTIVE: To observe the effect of low molecular weight saccharide in rhizoma polygonati on the immune function of normal mice and immunosuppression ones caused by cyclophosphamide.

目的:观察黄精中小分子糖对正常小鼠及对环磷酰胺所致免疫功能低下小鼠免疫功能的影响。

The expression of immunogenic epitopes of HBsAg on HBsAg-pulsed DCs was assessed in vitro.

在体外进行血树突状细胞脉负载的HBsAg致免疫的抗原决定簇的表达。

The expression of immunogenic epitopes of HBsAg on HBsAg-pulsed DCs was assessed in itro.

在体外进行血树突状细胞脉负载的HBsAg致免疫的抗原决定簇的表达。

D immunoglobulin is administered to Rh-negative,unsensitized patients to prevent isoimmunization.

为避免同种免疫,给未致敏的Rh血型阴性患者注射D免疫球蛋白。

The SPA-rich Staphylococcus aureus coated with the specific IgG was used as nephelometric immunoassay reagent and could lead to good results. On the basis of nephelometric immunoassay combined with immunomagnetic separation, the rapid automatic quantitative immunoassay for the detection of Shigella flexneri was established, which provides a new way for the rapid diagnosis and automatic quantitative analysis of pathogenic bacteria.

以福氏志贺菌的多抗血清分别致敏SPA包被的磁珠和富含SPA的金黄色葡萄球菌,制备特异的多抗磁珠对福氏志贺菌有一定的特异捕获与富集作用,抗体致敏的金黄色葡萄球菌作为协同凝集试剂与免疫比浊试剂对福氏志贺菌的自动、快速、定量检测具有较好的效果,免疫比浊分析结合免疫磁分离技术为病原菌的快速诊断和自动定量分析提供了新的思路。

The flower extract of Sesamum indicum L. could significantly improve the immune function in immune-suppressed mice.

脂麻花醇提取物能明显改善环磷酰胺所致免疫功能低下模型小鼠的免疫功能。

RESULTS: NK cells represent a unique subset of lymphocytes that have no restriction by MHC antigens and have the ability to lyses certain tumor cells without the requirement for prior immune sensitization of the host. In addition, NK cells can also produce cytokines and regulate the function of other immune cells. So, it is emerging to apply NK cells as therapeutic agents against a broad range of malignancies. In this respect, the anti-tumor activity of NK cells is the key factor of NK-cell-based immunotherapy.

结果:NK细胞是一种独特的淋巴细胞,对靶细胞的识别无MHC限制性,无需预先致敏即可直接杀伤肿瘤细胞,也可分泌细胞因子调节其他免疫细胞的功能,是机体天然免疫的主要承担者,也是获得性免疫的核心调节细胞,故NK细胞在抗肿瘤免疫中的地位越来越受到重视,随之增强NK细胞肿瘤杀伤活性的研究也逐步深入。

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