致

Meta-analyses showed that the response rate of TP (topotecan + cisplatin) regimen had no significant difference compared with EP regimen (etoposide + cisplatin) with OR 0.83 and 95%CI 0.63 to 1.09, but myelo-suppression such as leucopenia and thrombopenia was more severe with TP regimen; the response rate of monotherapy with topotecan was similar with that of CE (carboplatin + etoposide) regimen with OR 0.59 and 95%CI 0.22 to 1.60; the response rate of TEP (topotecan + etoposide + cisplatin) regimen was comparable with that of EP regimen with OR 1.37 and 95%CI 0.82 to –2.28, but myelosuppression and anemia were more severe with TEP regimen; the response rate with OR 0.97 and 95％CI 0.60 to –1.57, median time to progression with WMD –2.32 and 95％CI –5.72 to 1.09 and median survival time with WMD –1.65 and 95％CI –7.13 to 3.83 of IV topotecan were similar to those of oral topotecan, while neutropenia was more severe with IV topotecan.

Meta分析结果表明，TP 方案与EP方案的反应率相似 [OR 0.83， 95%CI (0.63，1.09)]，但具有相对高的致血小板下降的骨髓毒性；单药拓朴替康与CE方案的反应率相似 [OR 0.59， 95%CI (0.22，1.60)]；TEP方案（拓扑替康＋足叶乙甙＋顺铂）与EP方案的反应率相似 [OR 1.37， 95%CI (0.82，2.28)]，TEP方案致化疗后重度白细胞下降、重度血小板下降、重度血红蛋白下降均高于EP方案；口服拓扑替康与静脉滴注拓扑替康的化疗后反应率 [OR 0.97， 95％CI (0.60，1.57)]、中位疾病进展期 [WMD –2.32， 95％CI (–5.72， 1.09)]、中位生存期 [WMD –1.65， 95％CI (–7.13，3.83)] 相似，口服拓扑替康化疗后重度中性粒细胞下降明显低于静脉滴注拓扑替康。

Meta-analysis based on included studies showed that response rate of TP regimen has no statistic significance compared with EP regimen[OR0.83,95%CI(0.63-1.090)],but myelo-suppression such as leucopenia and thrombopenia is more severe; response rate of single topotecan has no statistic significance compared with CE regimen[OR0.59,95%CI(0.22-1.60)]; response rate of TEP regimen has no statistic significance compared with EP regimen [OR1.37, 95%CI(0.82-2.28)], but myelo-suppression such as leucopenia, thrombopenia and anemia is more severe; response rate of IV topotecan has no statistic significance compared with Oral topotecan[OR0.97, 95%CI(0.60-1.57)],so as median time to progression[WMD-2.32, 95%CI(-5.72,1.09)] and median survival time[WMD-1.65, 95%CI(-7.13,3.83)],while neutropenia is more sever in IV topotecan than Oral topotecan.

分析表明，TP方案与EP方案的反应率相似[OR0.83，95％CI(0.63-1.090)]，但具有相对高的致白细胞和血小板下降的骨髓毒性；单药拓扑替康与CE方案的反应率相似[OR0.59，95％CI(0.22-1.60)]；TEP方案与EP方案的反应率相似[OR1.37，95％CI(0.82-2.28)]，TEP方案致化疗后重度白细胞下降、重度血小板下降、重度血红蛋白下降均高于EP方案；口服拓扑替康与静脉滴注拓扑替康的化疗后反应率[OR0.97，95％CI(0.60-1.57)]、中位疾病进展期[WMD-2.32，95％CI(-5.72，1.09)]、中位生存期[WMD-1.65，95％CI(-7.13，3.83)]相似，口服拓扑替康化疗后重度中性粒细胞下降明显低于静脉滴注拓扑替康。

ResultsESC(the extract of Solidago canadensis L.) markedly prolonged the writhing latent period and decreased the times of writhing of mice induced by ip acetic acid, while it had no obvious effect on the pain threshold value in hot plate test. ESC significantly prolonged the tussive latent period of mice, decreased the tussive times and increased phenolsulfonphthalein excretion quantity of trachea of mice. ESC was nontoxic according to the acute toxicity test.

结果首次对国产加拿大一枝黄花进行了体内药理作用研究，发现加拿大一枝黄花提取物能显著延长醋酸致小鼠扭体潜伏期，减少扭体次数；但未明显提高热板法实验小鼠的痛阈值；能显著抑制浓氨水所致小鼠咳嗽潜伏期和咳嗽次数；显著增加小鼠气管的酚红排泌量；急性毒性实验表明加拿大一枝黄花提取物无明显毒性，既不引起小鼠死亡也不影响小鼠体重正常增加。

YR-1 can attenuate the toxicity of immune function and bone marrow induced by chemotherapy drugs DDP and TAX in condition of unaffecting the efficacy, suggest YR-1 possesses the protective effect on the damage of immune function and bone marrow indued by chemotherapy drugs.

在不降低DDP和TAX疗效的情况下，YR-1对化疗药物所致荷瘤动物免疫功能的降低和骨髓抑制具有明显的拮抗作用，提示YR-1对化疗所致的免疫功能损伤和骨髓损伤具有保护作用。

According to the experimental data,using the best square approach way,the linear extent magnetostriction properties equation of Terfenol-D material is made,then the magnetostriction properties equation under a unconstant preloading is educed.

根据实验数据，利用最佳平方逼近的方法，确定了Terfenol-D材料线性范围内的磁致伸缩特性方程，并进而得出了变载荷磁致伸缩特性方程。

The risk of becoming broadly sensitized after transplant was 11/69 (16%) if the recipient was unsensitized prior to transplant.

如果受者移植前未被致敏，则广泛致敏的可能性仅为11/69 (16%)。

Methods C3b sensitized yeast cells and C3b unsensitized yeast cells were used to detect C3b receptors and immune complex on red cells,method of xanthine oxidase was applied to detect SOD activity in red cells.

实验利用低碘饲料和碘化钾去离子水复制了不同碘营养状态的大鼠，采用C3b致敏和未致敏的酵母菌及黄嘌呤氧化酶法分别检测红细胞膜上的C3b受体、免疫复合物及红细胞内SOD的活性。

While detecting the patients with ureterolithiasis, if the width of renal pelvis is 0 mm, it is necessary to measure the width of another kidney and compare with them. If the width of ill renal pelvis is extended by 3 1 mm, the diagnosis of hydronephrosis can be established, then, combining with other signs, such as ureterectasis, the diagnosis of ureterolithiasis can be set up.

输尿管结石所致0 mm肾积水的发生率为 29 47％，超声诊断输尿管结石所致肾积水0 mm时应作两侧比较，当两侧集合系统宽度差别≥3 1 mm时，应考虑肾积水的存在，此时应结合临床、是否合并同侧输尿管扩张、合并结石等情况而作出肾积水的诊断。

She is especially good at the management of the eyeground diseases, such as ocular fundus bleeding from various reasons, retinal vascular diseases (such as diabetic retinopathy, retinal vein occlusion, retinal artery occlusion, retinal vasculitis etc.) from diabetes mellitus, hypertension, or various inflammation, retinal capillary hemangioma, vitreous hemorrhage caused by various retinal diseases, optic neuritis, ischemic optic neuropathy, retinal detachment, macular diseases (such as age related macular degeneration, central serous chorioretinopathy, central exudative chorioretinopathy etc.), and other complex diseases such as uveitic diseases and glaucoma etc.

特别是对眼底病如各种原因所致眼底出血；糖尿病、高血压、各种炎症所引起的视网膜血管病如糖尿病视网膜病变、视网膜静脉阻塞、视网膜动脉阻塞、视网膜血管炎症等；视网膜血管瘤病以及其他各种视网膜病所致玻璃体出血；视神经炎、视神经缺血、视网膜脱离、黄斑部疾病如老年性黄斑变性、中浆、中渗等及其他疑难病如葡萄膜炎，青光眼等的诊治积累了大量的临床经验。

Large VT mechanical ventilation can significantly activate the p-p38 and inflammatory cytokines, which may play an important role in VILI.快车资源*egv|'NS9+AS

大VT机械通气能显著激活p38通路以及致炎因子的表达，这可能是大鼠机械通气所致肺损伤的重要致病机制之一。

What would he tell Judith and the children?

他将怎样告诉朱迪丝和孩子们呢？

I this is at that time, the opinion with peacockish true girl is full of in a heart.

这就是当时的我，一个心中布满虚荣的女孩子真实的想法。