至高的

Burden of Disease – HPV 6, 11, 16, 18 Amongst Men HPV Types Condition Prevented 16 and 18 6 and 11 70% anal cancers and AIN Some penile / oropharynx cancers Reduced transmission to women 90% of genital warts Reduced transmission to women

感染肛门生殖道的 HPV 可以区分为两大类，一为导致生殖道疣或良性子宫颈病变的低危险性病毒型，共 10 至 15 种；另一为与侵袭性子宫颈癌、生殖道癌相关的高危险性病毒型，共 15 至 20 种。

The growth inhibiting rate of T24 cell lines were detected by MTT methods, apoptosis of cells were detected by flow cytometry, the mechanism of apoptosis was analyzed by detecting the protein expression of Bcl-2, Bax, Caspase-9, Caspase-3 and cytoplastic protein Cytochrome C. 4 We injected live T24 cells into the subcutaneous space of nude mice and successfully built up the animal model of bladder carcinoma. The effect of CS-PAA-EPI polymer magnetic microspheres targeting chemotherapy was investigated by HE staining, TUNEL ,tumor weight and volume inhibition rate. Results: 1 TEM revealed that the CS-PAA polymer magnetic microspheres were regular spherical shape,the average diameter was 80nm in dry condition. By controlling the pH value of the medium,polymers had positive or negative zeta potential. VSM showed the CS-PAA polymer magnetic microspheres had superparamagnetic. The diameter of CS-PAA-EPI polymer magnetic microspheres were 200nm in solution by DLS examining,the embedding ratio was 20%,the EPI loading rate was 15%, which was higer than reported in other articles. 2 Raw eye observation found that the rat"s bladder of treatment group was brown color,which meaned the aggregation of iron particles, compared with the control group, iron stain found iron particles were assembled in rat"s bladder of the treatment group, the amount of iron particles in liver and spleen were less obviously.

研究结果：1合成的CS-PAA磁性聚合物微球呈球形，大小均一，TEM测定其干态下粒径为80nm左右，磁化曲线证实具有超顺磁性，具有一定的PH敏感性，固载表柔比星后，水溶液性状稳定，无沉淀物，DLS测定直径约200nm左右，测定载药率为15％，较文献报道高，包封率为20％。2肉眼观察试验组大鼠膀胱表面呈褐色，可见大量的Fe粒子聚集，普鲁士兰染色法显示，试验组大鼠膀胱壁内有大量的Fe粒子，分布至膀胱壁全层，与对照组大鼠相比，试验组大鼠的肝、脾内的Fe粒子聚集量明显降低；HPLC测定结果与Fe染色相同；高剂量磁性CS-PAA-EPI生理盐水组及单纯EPI生理盐水组均在给药后14天出现血肌酐和尿素氮的升高，其他组大鼠血生化指标没有明显变化。3MTT法发现，高、中、低剂量磁性CS-PAA-EPI生理盐水组在外加磁场的协同作用下杀伤T24细胞效应明显高于单纯的EPI生理盐水组，FCM发现试验药物组可引起明显的肿瘤细胞凋亡，试验药物治疗组细胞胞浆内出现了由线粒体释放出的细胞色素C，试验组细胞Bcl-2蛋白减少，Bax蛋白变化不明显，Caspase-3、Caspase-9蛋白受到了激活活化。4高、中、低剂量磁性CS-PAA-EPI生理盐水组的瘤重抑制率和瘤体积抑制率均明显高于单纯的EPI生理盐水组(P＜0.01)，其中高剂量组的抑制率最高。

The company introduced first class key equipment from abroad via technical reform. The company has been successfully developed series of popular new products such as imitate silk, pure silk, polyester discharge printing, devorative fabric printing, cotton and polyester/cotton printing, etc. It makes the company has strong competitive ability at home and abroad.

企业通过生产技术改造，从国外引进能生产高档次、多套色、高精度、高附加值产品的关键设备，使新产品、新花色、新工艺开发如虎添翼，成功组织生产了风行市场的涤纶仿真丝、真丝、涤纶雕印、装饰布印花、全棉、涤棉TC布印花等一系列新产品，使产品辐射至全国各地及海内外，增强了企业在国际、国内的市场竞争力。

In the second part, an HPLC (High Performance Liquid Chromatography) was developped to analyze the active pharmacological ingredients in fresh and dry ginger capable of separating zingerone, [6]-gingerol and [6]-shogaol within 65 minutes. Using the above method, our study conducted an analysis on 10 batches of fresh and dry ginger sold on the market.

本研究利用前述分析法，对市售生姜与乾姜各10批进行分析，结果显示，生姜中无zingerone，[6]- gingerol的含量为1.63至2.82 mg/g，[6]-shogaol的含量为0.089至0.120 mg/g，[6]- gingerol平均含量远高於[6]-shogaol，约为20倍左右。

If the ratio or the concentration of 2, 4-D was higher, the callus formed quickly, but it was hygrophanous, and easy to necrosis, conversely, if the ratio or the concentration of 2, 4-D was lower, the callus appeared very slowly or could not form, and adventitious root formed directly or indirectly.

比值较高（或2，4-D浓度较高）时愈伤组织出现的时间较早，但愈伤色泽不好，呈半透明水渍状，易于褐化死亡，而比值较低时，愈伤出现得很慢或不形成愈伤，且易于直接或再分化形成不定根；这些不定根长至1.5-2.0cm时就不生长，并逐渐褐化。

The lip gene has higher potential for lipid-rich food wastes treatment compared to the lipA gene.

此脂解？对C10至C12酯类及C8至C10之三甘油脂有较佳的分解活性，lip基因比lipA基因较有被应用於高油脂厨余分解油脂的应用潜力，因为在选殖这些脂解？

From the base to the crown in axial, the vessel-elements proportion increases in fluctuation, contrary to the ray proportion. The fiber proportions in the regions of base and crown are less than that in the trunk of tree, and fluctuate at 65% or so. The parenchym proportion increases quickly to the 1.3m height of tree, reaching the maximum at 9.52%, and then decreases quickly to the 3.3m height of tree (8.90%); afterward it leveled off and increases slightly.

组织比量轴向变异表现为随树高增加导管比量波动性递增，与木射线比量相反；纤维比量在近根区和近冠区稍小，而主干部稍大，并在65%左右波动；轴向薄壁细胞比量先随树高增加急剧增加，到1.3m树高处达最大值（9.52%）后又急剧降低至3.3m树高处的8.90%，以后基本稳定并在波动中略有增加。

Results: Up to date, most of the found chemical compostition of Flos Lonicerae conclude essential oil, flavonoid, organic acid, triterpenoid and microelement; The pharmacal researches show that it can antagonize pathogenic microorganism, anticatarrhals,...

结果 ：至目前为止，已发现的化学成分主要有挥发油、黄酮类、有机酸、三萜类、无机元素等；药理研究表明金银花具有抗病原微生物、抗炎、解热、保肝、抗生育、止血、免疫调节、降血脂、中枢兴奋等作用；临床上主要用于多种感染、各种炎症、高热症、高脂血症、肿瘤放疗、化疗口干症等；金银花质量标准主要以其主要成分绿原酸为指标，检测方法多采用薄层色谱法和高效液相色谱法。

Merseyside derbies are very quick and frantic in the first 15-20 minutes and the tempo and intensity is very high.

默西塞德德比在刚开始的15至20分钟会拥有高节奏和高强度。

A simple and opeative method of discharging highly metalized pellets is obtained: first cooling the pellets to about 900℃, then discharging them directly into the open air with the metallization rate of 90%.

4本文研究得到一种较为简单有效的高金属化球团出炉冷却方式：在炉内将高金属化球团冷却至900℃左右后直接在空气中出料，金属化率可保持90％。

The labia have now been sutured together almost completely.The drains and the Foley catheter come out at the top.

此刻阴唇已经几乎完全的缝在一起了，排除多余淤血体液的管子和Foley导管从顶端冒出来。

To get the business done, I suggest we split the difference in price.

为了做成这笔生意，我建议我们在价格上大家各让一半。