自身免疫作用

Methods With guinea pig spinal cord homogenate in complete Freund's adjuvant or MBP in complete Freund's adjuvant and Bordetella pertussis vaccine was injected intradermally to induce EAE in Wistar rats. To investigate the suppression of clinical and histological manifestations of the disease when animals were fed with MBP before or after disease induction.

目的 建立实验性自身免疫性脑脊髓炎动物模型，探讨口服自身抗原诱导免疫耐受对大鼠EAE的防治作用方法在普通Wistar大鼠经1次足跖真皮内注射完全弗氏佐剂-豚鼠全脊髓匀浆或完全弗氏佐剂-髓鞘碱性蛋白乳剂加百日咳疫苗诱发EAE疾病；另在大鼠致炎及发病后口服髓鞘碱性蛋白，观察其对EAE的防治作用。

Methods With guinea pig spinal cord homogenate in complete Freund's adjuvant or MBP in complete Freund's adjuvant and Bordetella pertussis vaccine was injected intradermally to induce EAE in Wistar rats.

目的 建立实验性自身免疫性脑脊髓炎动物模型，探讨口服自身抗原诱导免疫耐受对大鼠EAE的防治作用。

Objective To study the morphological and functional effect of pinealectomy on CRH neurons in paraventricular nucleus of rat hypothalamus as well as thefunction of melatonin supplementation, enrich the research of the effect of pinealbody and melatonin on hypothalamic-pituitary-adrenal axis,provide theoreticalevidence of the effect of pineal body and melatonin on immune function andimmune-associated disease such as tumor and autoimmune disease.

目的： 研究松果体及其褪黑素对大鼠下丘脑室旁核CRH 神经元形态和功能的影响以及补充褪黑素的作用，丰富松果体及褪黑素对下丘脑——垂体——肾上腺轴影响的形态及功能方面的研究，为进一步揭示松果体及褪黑素对免疫功能以及免疫相关性疾病如肿瘤、自身免疫性疾病等的影响机制提供理论依据。

We examined the properties of DC associated with immune suppression in NOD mice by insulin injection subcutaneously and ability to suppress diabetes transfer by diabetogenic effect cells in secondary NOD severe combined immunodeficiency recipients.

NOD小鼠皮下注射牛胰岛素诱导免疫抑制，以血糖检测、胰腺组织学分析和胰岛beta细胞凋亡分析观察自身抗原的免疫保护作用，分离骨髓树突状细胞细胞，流式细胞术分析细胞表面抗原，混合淋巴淋巴细胞反应测定细胞功能。

Apoptotic cells have immunogenicity,and may be the major source of autoantigens in lupus BXSB mice.Lupus genetic factors and Yaa gene can potentiate the immunogenicity of apoptotic cells or accelerate their inducing the lupus nephritis.

凋亡细胞具有免疫原性，它可能是狼疮性BXSB小鼠体内自身抗原的主要来源；狼疮性遗传因素和Yaa基因能促进凋亡细胞的免疫原性和增强凋亡细胞的致肾炎作用。

Apoptotic cells have immunogenicity,and may be the major source of autoantigens in lupus BXSB mice.Lupus gecnic factors and Yaa gene can potentiate the immunogenicity of apoptotic cells or accelerate their inducing the lupus nephritis.

凋亡细胞具有免疫原性，它可能是狼疮性BXSB小鼠体内自身抗原的主要来源；狼疮性遗传因素和Yaa基因能促进凋亡细胞的免疫原性和增强凋亡细胞的致肾炎作用。

ConclusionApoptotic cells have immunogenicity,and may be the major source of autoantigens in lupus BXSB mice.Lupus genetic factors and Yaa gene can potentiate the immunogenicity of apoptotic cells or accelerate their inducing the lupus nephritis.

结论凋亡细胞具有免疫原性，它可能是狼疮性BXSB小鼠体内自身抗原的主要来源；狼疮性遗传因素和Yaa基因能促进凋亡细胞的免疫原性和增强凋亡细胞的致肾炎作用。

Apoptotic cells have immunogenicity,and may be the major source of autoantigens in lupus BXSB mice.Lupus genetic factors and Yaa gene can potentiate the immunogenicity of apoptotic cells or accelerate their inducing the lupus nephritis. Apoptosis; Mice,BXSB; Lupus erythematosus,systemic

凋亡细胞具有免疫原性，它可能是狼疮性BXSB小鼠体内自身抗原的主要来源；狼疮性遗传因素和Yaa基因能促进凋亡细胞的免疫原性和增强凋亡细胞的致肾炎作用。

Apoptotic cells have immunogenicity,and may be the major source of autoantigens in lupus BXSB mice.Lupus genetic factors and Yaa gene can potentiate the immunogenicity of apoptotic cells or accelerate their inducing the lupus nephritis. Apoptosis; Mice,BXSB; Lupus erythematosus,systemic

凋亡细胞常识具有免疫病毒原性，它可能流产是狼疮性BXSB小鼠体内自身抗原的主要来源；狼疮性遗传因素和Yaa基因能促进凋亡细胞常识的免疫病毒原性和增强凋亡细胞常识的致肾炎作用。

In this autoimmune disease the action of TSI's predominates over that of TGI's .

此种自身免疫性疾病是由于甲状腺刺激免疫球蛋白的作用超过了甲状腺生长刺激免疫球蛋白的作用。

As she looked at Warrington's manly face, and dark, melancholy eyes, she had settled in her mind that he must have been the victim of an unhappy attachment.

每逢看到沃林顿那刚毅的脸，那乌黑、忧郁的眼睛，她便会相信，他一定作过不幸的爱情的受害者。

Maybe they'll disappear into a pothole.

也许他们将在壶穴里消失