自身免疫

3H-TdR pulse labeling and autoradiograph results and Gimsa stained results suggest that the DNA synthesis, chromosome condensation are not affected in HAP42 multinulceuse cells.

以α-Tubulin和人类自身抗中心体免疫血清进行免疫荧光染色发现多核细胞中有单极纺锤体的形成，γ-tubulin分布比对照细胞弥散，着色较弱。

These diseases can occur together in defined syndromes with distinct pathophysiology and characteristics: autoimmune polyendocrine syndrome I, autoimmune polyendocrine syndrome II, and the immunodysregulation polyendocrinopathy enteropathy X-linked syndrome.

这些疾病可以与一些有不同病生理和特征的确定的综合症一起发生：多发性自身免疫性内分泌综合征1型，多发性自身免疫性内分泌综合征2型，免疫调节不能性多发性内分泌腺X-连锁肠病综合征。

Methods With guinea pig spinal cord homogenate in complete Freund's adjuvant or MBP in complete Freund's adjuvant and Bordetella pertussis vaccine was injected intradermally to induce EAE in Wistar rats. To investigate the suppression of clinical and histological manifestations of the disease when animals were fed with MBP before or after disease induction.

目的 建立实验性自身免疫性脑脊髓炎动物模型，探讨口服自身抗原诱导免疫耐受对大鼠EAE的防治作用方法在普通Wistar大鼠经1次足跖真皮内注射完全弗氏佐剂-豚鼠全脊髓匀浆或完全弗氏佐剂-髓鞘碱性蛋白乳剂加百日咳疫苗诱发EAE疾病；另在大鼠致炎及发病后口服髓鞘碱性蛋白，观察其对EAE的防治作用。

Methods With guinea pig spinal cord homogenate in complete Freund's adjuvant or MBP in complete Freund's adjuvant and Bordetella pertussis vaccine was injected intradermally to induce EAE in Wistar rats.

目的 建立实验性自身免疫性脑脊髓炎动物模型，探讨口服自身抗原诱导免疫耐受对大鼠EAE的防治作用。

In order to explore relationship between pathological classifications and humoral auto immune status, the serum,cerebrospinal fluid and nucleus pulposus of 28 disc herniation patients were examined for the production of IgG and IgM by rate nephelometry and immunohistochemical protocol.

为探讨腰椎间盘突出症的不同病理分型和自身体液免疫状态之间的相互关系，采用速率散色比浊法和免疫组化法对28 例腰椎间盘突出症患者血清、脑脊液和髓核组织中IgG、IgM 进行测定。

Methods To detect autoantibodies in 16 cases of sera from patients with pemphigus by immunofluorescence.

以牛舌粘膜作为底物，分别应用间接免疫荧光法和免疫印迹技术检测16例天疱疮患者血清中IgG型自身抗体。

Objective To study the morphological and functional effect of pinealectomy on CRH neurons in paraventricular nucleus of rat hypothalamus as well as thefunction of melatonin supplementation, enrich the research of the effect of pinealbody and melatonin on hypothalamic-pituitary-adrenal axis,provide theoreticalevidence of the effect of pineal body and melatonin on immune function andimmune-associated disease such as tumor and autoimmune disease.

目的： 研究松果体及其褪黑素对大鼠下丘脑室旁核CRH 神经元形态和功能的影响以及补充褪黑素的作用，丰富松果体及褪黑素对下丘脑——垂体——肾上腺轴影响的形态及功能方面的研究，为进一步揭示松果体及褪黑素对免疫功能以及免疫相关性疾病如肿瘤、自身免疫性疾病等的影响机制提供理论依据。

Our hypothesis is that (1) many strains of rats simply cannot mount a sufficiently vigorous destructive immune-response to outstrip the liver ' s relatively great capacity to protect itself from immune-response damage and that (2) the systemic unresponsiveness observed is due to concentration of the recipient ' s donor-specific lymphocytes at the site of the liver transplant.

我们的假设是：（1）许多种老鼠纯粹就是无法发起一场足够强的摧毁性免疫应答（immune-response），以压倒肝脏相对较强的保护自身免遭免疫应答损害的能力；（2）所观察到的系统性无应答状态，是由于受移植者的供者特异性淋巴细胞集结在肝脏移植物所在的部位所致。

Methods ANAs were tested in 64 patientswith SSc and 30 healthy controls by IIF and IB.

分别采用间接免疫荧光法和免疫印迹法对64例SSc患者和30例健康对照者血清中6种自身抗体进行测定。

We examined the properties of DC associated with immune suppression in NOD mice by insulin injection subcutaneously and ability to suppress diabetes transfer by diabetogenic effect cells in secondary NOD severe combined immunodeficiency recipients.

NOD小鼠皮下注射牛胰岛素诱导免疫抑制，以血糖检测、胰腺组织学分析和胰岛beta细胞凋亡分析观察自身抗原的免疫保护作用，分离骨髓树突状细胞细胞，流式细胞术分析细胞表面抗原，混合淋巴淋巴细胞反应测定细胞功能。

As she looked at Warrington's manly face, and dark, melancholy eyes, she had settled in her mind that he must have been the victim of an unhappy attachment.

每逢看到沃林顿那刚毅的脸，那乌黑、忧郁的眼睛，她便会相信，他一定作过不幸的爱情的受害者。

Maybe they'll disappear into a pothole.

也许他们将在壶穴里消失