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It was found from the structure-electrochemical studies of myoglobin that (1) electroreduction induces the T→R configuration transition with peak shift in CD spectra and without umbrella conversed effect, which proved that umbrella conversed effect is mainly the cooperation of four subunits in hemoglobin;(2) the mechanism of EC with adsorption of reduction product and parameters have also been obtained.

肌红蛋白的结构-电化学研究中发现:(1)电化学还原诱导了肌红蛋白的T→R构型转化,伴随着CD谱的峰位移,但没有象血红蛋白那样明显伞翻转效应,表明伞翻转效应是多个亚基共同作用的结果;(2)获得肌红蛋白电化学还原的EC机理,并伴随产物吸附的自阻碍过程及其参数。

Monofilm of silane on the surface of the glass substrates is prepared via the method of self-assembled monolayers, Hf (SO4)24H2O and HCI are used as raw materials, HfO2 thin films are prepared on the active groups of the alkyl silane by the liquid phase deposition.

利用自组装单层膜技术,在玻璃基板上生长有机硅烷单分子膜层,以Hf(SO4)24H2O和HCI配制HfO2前驱液,通过液相沉积在硅烷的功能性官能团上诱导生成二氧化铪薄膜。

The soil and bark samples collected from Yunnan, Hebei and Shanxi provinces of China, and also from Vietnam, were used as the materials in this experiment. And dung pellets of rabbits or goats that had been autoclaved can be used to induce many kinds of fruiting bodies of the Myxobacteria in different colors, sizes, and shapes. We isolated and purified Myxobacteria strains with the improved method which was found by our laboratory.

本实验以采集自越南以及我国的云南、河北、陕西各地的土样和各种树皮、腐木作为实验材料,利用兔、羊粪球和滤纸作为基质诱导出多种颜色丰富、形态多样的粘细菌子实体,采用本实验室摸索出的较为有效的纯化粘细菌的方法,在实验器材上用24孔细胞培养板代替传统的平皿,有效地缩短了粘细菌的纯化周期,提高了分离纯化的效率。

Reactions of 2-methyl-1,4 naphthoquinone with human telomeric DNA and telomerase RNA ESR spin elimination has been used with 4-oxo-TEMPO as spin trap. The reactivities of 3VK3* with telomeric DNA, template of telomerase RNA and its L6-P6 region have been confirmed respectively. The results show that the reactivity of 3VK3* with polynucleotides is directly proportional to their G amount, and the one for reaction of 3VK3* with telomeric DNA is the highest in polynucleotides. 2. Reactions of 2-methyl-1,4 naphthoquinone with nucleosides, nucleotides ESR spin elimination has been used with 4-oxo-TEMPO as spin trap.

2-甲基-1,4萘醌与端粒DNA及端粒酶RNA亚基光敏反应性的研究应用ESR自旋消减法,对2-甲基-1,4萘醌(VK3)与端粒DNA重复序列、端粒酶RNA亚基模版序列、端粒酶RNA亚基L6-P6发夹区关键序列的光敏反应性进行了研究,结果表明,在一定波长照射下,明显诱导VK3与上述寡聚核苷酸反应,其反应性大小与核酸中鸟嘌呤含量正相关,其中端粒DNA序列反应性最强。

Includes growth factors including bone morphogenetic protein from the solidification calcium phosphate, has induction osteogenous energy, may sharpen the bone ability, is suitable for the marrow compound transplant for nonnegative heavy or carries a heavy load lowly the area tumorous bone damage repair.

自固化磷酸钙含有骨形态发生蛋白等生长因子,具有诱导成骨性能,可提高成骨能力,与骨髓复合移植适用于非负重或低负重区肿瘤性骨缺损的修复。

Thirty patients with acute promyelocytic leukemia were observed between September 1977 and October 1985. Bleeding diathesis with petechiae or ecchymosis (80%) was the most common presenting symptom. Seventeen of 24 patients with pretreated coagulation studies were diagnosed to have disseminated intravascular coagulation. Six out of 11 patients died from intracranial hemorrhage after a mean of 2.5 days of hospitalization without any treatment. DIC was responsible for death in most cases. Induction therapy with anthracycline and cytosine arabinoside combined with prophylactic heparin infusion was carried out in the remaining 19 patients. Two patients were incompletely treated. Eight out of 17 patients achieved complete remission after a mean of 63 days following chemotherapy. The remission rate was 47%.

自1977年9月至1985年10月,观察30位急性前骨髓球性白血病病帣,临床上诊断时初发症状,主要为出血现象,尤其以瘀斑出血最多,占80%。24位病人作治疗前凝血机能检查,17位出现播散性血管内凝固症候群。11位病人没有接受治疗,其中6位经诊断后平均2.5天内死於脑内出血,凝血机能检验显示5位有播散性血管内凝固症候群。19位病人接受anthracycline与ara-C并用预防性肝素静脉滴注作缓解诱导治疗,2位不完全治疗,其余17位中有8位经过平均63天之化学治疗得到完全缓解,缓解率47%。

Both Fas and NO can lead chondrocyte apoptosis respectively and cause articular cartilage destruction. IGF-Ⅰ, TGF-β, bFGF, BMP and other growth factors are polypeptide agents that can influence cell activity by signal convection. They can accelerate chondrocyte proliferation and proteoglycan synthesis, play the local regulation action on formation and plerosis of bone and cartilage tissue by autocrine or paracrine. They have the ability to induce cartilage formation. Some investigations showed that growth factors can influence chondrocyte metabolism, synthesis of specific Ⅱ type collagen and proteoglycan by co-operation and inhibition. 1. 3 Situation of OA therapeutics The therapeutic methods of OA mainly comprised non-drug treatment, drug treatment, operation treatment, tissue and genetic engineering, et al. Drug treatment is the chief method among them.

若其活性发生改变,则将导致关节软骨基质成分的丢失和进行性破坏;软骨细胞凋亡与OA的发病密切相关,Fas与NO可各自独立介导软骨细胞凋亡,造成关节软骨破坏;IGF-Ⅰ、TGF-β、bFGF、BMP等生长因子是一组通过细胞间信号传递影响细胞活动的多肽因子,具有促进细胞生长、增殖与合成等作用,可通过自分泌或旁分泌方式对骨和软骨的形成和修复起局部调节作用,可促进软骨细胞增殖、分化与蛋白多糖的合成,具有较强的诱导软骨形成的能力,研究表明多种生长因子相互促进、相互抑制,以协同或拮抗方式影响软骨细胞代谢,影响软骨细胞特异性Ⅱ型胶原和蛋白多糖的合成分泌。

The biological characteristics and toxicity of Russula subnigricans Hongo was studied for the first time from ecology and morphologic characteristics and histology, the orthogonal experiment of the optimum culture condition, the analysis of components, apoptosis of the cells from little white rat liver and kidney induced by extract of Russula Subnigricans Hongo,to the histopathologic changes observation of little white rat liver and kidney through ecological observation, light microscopy and scanning electron microscopy, reversed-phase high performance liquid chromatography, agarose gel electrophoresis, transmission electron micioscopy.

利用菌种分离技术、光镜技术、电镜技术、高效液相色谱技术、毒理实验技术、电泳方法等对亚稀褶黑菇的生物学特性和毒性机理进行了研究,主要包括以下内容:亚稀褶黑菇的生态学和组织学研究、菌种分离培养、扫描电镜观察、成分分析、粗毒液诱导小自鼠肝肾细胞凋亡,小白鼠中毒后肝肾细胞透射电镜观察,研究结果如下: 1。

The amount of neuron at 2st week for EG and CC were 36.50±1.78/EF and 19.70±3.71/EF respectively, with the percentage of (43.60±4.83)% and (39.04±3.87)% for EG and CG, which had significant difference (P.05) Conclusion: Self-assembled IKVAV peptide nanofibers, which can degrade the neuron mortality as well as promote neurite sprouting and growth, is a bioactivity scaffold, it can serve as a superordinary nerve tissue engineering scaffold.

自组装IKVAV多肽纳米支架能降低神经元的死亡率,并诱导轴突的发生和生长,具有支架及生物活性双重作用,可作为神经组织工程支架材料。

However, if we use 99% nitrogen gas (N2) as the atmosphere, substituting for air, the viscoelastic parameters reveal an undiscernible change, different from that in an air atmosphere.

采用动态时间扫描的方法对200℃空气气氛中HDPE模量变化进行实时检测,发现HDPE的氧化交联存在与一般的自由基聚合相类似的诱导、自加速和增长三个阶段。

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I didn't watch TV last night, because it .

昨晚我没有看电视,因为电视机坏了。

Since this year, in a lot of villages of Beijing, TV of elevator liquid crystal was removed.

今年以来,在北京的很多小区里,电梯液晶电视被撤了下来。

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我比喻得过头了。