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In case Ⅱ, emergence of SLE in pre-existing hypothyroidism exacerbated the autoimmune condition with thyroid hypofunction and lupus activity.

在第二个病例中,在原先就存在的甲状腺功能低下症的病人所新发生的全身性红斑狼疮可能与自体免疫的情况恶化有关,而自体免疫的情况恶化包含了甲状腺功能低下症的再发与新发生的全身性红斑狼疮。

The fusion rate of allograft+rhBMP-2 in lumbar posterolateral intertransverse fusion exeperiment in rabbits was 100%, and superior to autologous iliac crest and sustitute it.

得出结论:同种冷冻干燥异体骨+rhBMP-2复合物在兔子腰椎后外侧融合实验中,优于自体髂骨,可以取代自体髂骨,其融合率为100%,消除了假关节的发生。

Objective: The experiment will to observe: 1、the compound composed of carriers and rhBMP-2 excels or is similar to autologous iliac crest in posterolateral intertransverse spine arthrodesis in rabbits, 2、it may eliminated thd nonuions, 3、To explore the biologic process in spine arthrodesis and the role that accelaterated spine arthrodesis, 4、the roles of HA in spine fusion, by those compounds are used in posterolateral intertransverse fusion in rabbits.

目的:本实验通过rhBMP-2、HA复合物在兔子腰椎后外侧横突间融合的过程,观察了解:(1)rhBMP-2复合物在兔子腰椎后外侧横突间融合中,其作用能否优于或至少与自体髂骨相同,能否取代自体髂骨,免去取骨术。(2) rhBMP-2复合物的应用能否消除不融合的发生。(3)进一步了解脊柱融合的生物学过程,及rhBMP-2在脊柱融合生物学过程中所起的作用。(4)探讨HA在脊柱融合中的作用。

Results: At five weeks, the radiographically and manually determined fusion rate for autologous bone graft was 50%(4/8animals), compared with 100% and 50%(8/8 and 4/8 anilmals) for groups in which fusions were done by using allograft and xenograft augumented with rhBMP-2. Xenograft+HA used in posterolateral intertransverse arthrodesis yielded a fusion rate of 0%(0/8 animals).

结果:手动试验示:1、自体髂骨组即对照组融合率为50%:2、各实验组融合率分别为:同种冷冻干燥异体骨+rhBMP-2组为100%;异种冷冻干燥骨+rhBMP-2组为50%;异种冷冻干燥骨+HA组为0%。X软片示:1、自体髂骨组即对照组X线评分均值为2.75分,融合率为62.5%;2、各实验组结果分别为:同种冷冻干燥异体骨+rhBMP-2组X线评分均值为4分,融合率为100%:异种冷冻干燥骨+rhBMP-2组X线评分均值为2.62分,融合率为62.5%。

Hours after operation, most nerve cells disappeared and the glial cells were degenerated. There were many mono-nucleus cells infiltrating in transplantation group while a few in control group. One week after operation, tissues in the infarction zone were liquescent with many monocaryons and lymphocytes infiltrating around them in control group.

术后48 h神经细胞大片消失,胶质细胞变性,自体骨髓干细胞移植组有大量单个核细胞浸润,对照组相对较少。1周后对照组梗死区脑组织液化变软,坏死灶周围可见较多的单核和淋巴细胞浸润;自体骨髓干细胞移植组大鼠部分坏死灶被新生毛细血管和胶质细胞增生修复,炎性细胞浸润不明显。

Metal prosthesis has problems such as sensitivity to defect, loosening, breakage, bad histocompatibility and nondegradation.

自体骨虽然是理想的骨缺损修复材料,但自体取骨增加了患者的创伤和痛苦,并且供骨的来源有限,难以满足大段骨移植的要求;金属假体对缺口敏感,存在松动、断裂、组织相容性差、不可降解等问题。

Autogenous bone is an ideal material to repair bone defect, however, autogenous bone harvest increases patient trauma and pain. Moreover, its source is very limited, and it could not meet the requirement to repair large-segment transplantation. Metal prosthesis has problems such as sensitivity to defect, loosening, breakage, bad histocompatibility and nondegradation.

自体骨虽然是理想的骨缺损修复材料,但自体取骨增加了患者的创伤和痛苦,并且供骨的来源有限,难以满足大段骨移植的要求;金属假体对缺口敏感,存在松动、断裂、组织相容性差、不可降解等问题。

Local defects in bone as a result of trauma, neoplasm, infection, or congenital diseases are usually filled in and repaired with autografts The fresh autografts are considered to have the highest osteogenous capacity and no immune reaction.

外伤,肿瘤或感染施行骨切除或某些先天性疾病等原因引起的骨缺损常用自体骨填补,修复,其主要原因是自体新鲜骨成骨能力好,无免疫排斥反应。

Methods Twelve patients (12 eyes) with sever symblepharon and pseudo-pterygium were treated for symblepharon resection, then autologous oral mucosa was transplanted for reconstruction of the palpebral conjunctiva and fonix, amniotic membrane and conjunctival limbal grafts for bulbar conjunctiva and corneal surface reconstruction.

方法对12例12眼有严重睑球粘连及假性胬内的患者,进行睑球粘连松解后,应用自体口唇粘膜移植进行睑结膜和穹窿结膜修复,羊膜和自体结角膜缘组织瓣移植重建球结膜和角膜表面,观察其临床效果。

To pay attention to carry out effective cardiopulmonary resuscitation, hemostasis by compression and deep vein intubation rapidly in the initial stage of emergency. The carotid shunt tube plays an important role in severe carotid injury and re-establishment process. We use external jugular vein to transplant and re-establish,which are rung with artificial blood vessels for the long distance carotid injury and achieved the best result. We expose as fully as possible for the hepatic venae and the posthepatic post caval injury,and adopt effective methods to stop bleeding and repair. The application of blood shunt pump could raise the success rate for those severe patients. The self-double vastransplantation with both ends being all trousers-style one opening solve some problems such as there are no suitable caliber self-transplantation blood vessels and the artificial blood vessels are easy to occur obliteration for long-term and so on for the great or middle blood vessels.We use improved Fogarty duct and anterograde intubation to eliminate thrombus could eliminate thrombus effectively and avoid accessory injury for the deep vein injury and extensive thrombosis.

抢救初期要注意进行有效的心肺复苏、压迫止血和快速进行深静脉插管;颈动脉转流管在严重颈动脉损伤重建过程中有重要作用;对长距离颈动脉损伤用颈外静脉移植外环包人造血管重建,可取得最佳效果;对肝静脉及肝后下腔静脉损伤,要充分暴露,采用有效方法止血和修复,对病情极危重的凶险性出血者,血液转流泵的应用可提高成功率;对大、中血管损伤,两端均为裤式单开口自体双血管移植,解决了无适宜口径自体移植血管和应用人造血管远期易闭塞等问题;对深静脉损伤并广泛血栓形成者,应用改进的Fogarty导管和顺行插管取栓法,可有效取栓并避免了副损伤。

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As she looked at Warrington's manly face, and dark, melancholy eyes, she had settled in her mind that he must have been the victim of an unhappy attachment.

每逢看到沃林顿那刚毅的脸,那乌黑、忧郁的眼睛,她便会相信,他一定作过不幸的爱情的受害者。

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