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Methods 24 rabbits were randomly divided into control and treatment groups. There were 12 rabbits (24 articular genus) in every group. Osteoarthritis model was established by injection of caroid in articular genu intracavitary. Rabbits with osteoarthritis were interfered by Duhuojisheng decoction.

将24只兔随机分为2组,即对照组和治疗组,各12只,24个膝关节,采用兔膝关节腔内注入木瓜蛋白酶造成骨关节炎的病理模型,以独活寄生汤浓缩液喂食饲养,于治疗后1、3、5 周分别抽取关节液,采用双抗体夹心酶联免疫吸附法,分别测定兔膝关节液中IL-1及TNF 表达水平。

The re were 12 rabbits (24 articular genus) in every group. Osteoarthritis model was established by injection of caroid in articular genu intracavitary. Rabbits with osteoarthritis were interfered by Duhuojisheng decoction. The expression of IL-1 and TNF from synovial fluid in rabbit with osteoarthritis were measured by double antibody sandwich ELISA 1, 3, 5 weeks after treatment.

将24只兔随机分为2组,即对照组和治疗组,各12只,24个膝关节,采用兔膝关节腔内注入木瓜蛋白酶造成骨关节炎的病理模型,以独活寄生汤浓缩液喂食饲养,于治疗后1、3、5 周分别抽取关节液,采用双抗体夹心酶联免疫吸附法,分别测定兔膝关节液中IL-1及TNF 表达水平。

There were 12 rabbits (24 articular genus) in every group. Osteoarthritis model was established by injection of caroid in articular genu intracavitary. Rabbits with osteoarthritis were interfered by Duhuojisheng decoction. The expression of IL-1 and TNF from synovial fluid in rabbit with osteoarthritis were measured by double antibody sandwich ELISA 1, 3, 5 weeks after treatment.

将24只兔随机分为2组,即对照组和治疗组,各12只,24个膝关节,采用兔膝关节腔内注入木瓜蛋白酶造成骨关节炎的病理模型,以独活寄生汤浓缩液喂食饲养,于治疗后1、3、5 周分别抽取关节液,采用双抗体夹心酶联免疫吸附法,分别测定兔膝关节液中IL-1及TNF 表达水平。

Osteoarthritis model was established by injection of caroid in articular genu intracavitary. Rabbits with osteoarthritis were interfered by Duhuojisheng decoction. The expression of IL-1 and TNF from synovial fluid in rabbit with osteoarthritis were measured by double antibody sandwich ELISA 1, 3, 5 weeks after treatment.

将24只兔随机分为2组,即对照组和治疗组,各12只,24个膝关节,采用兔膝关节腔内注入木瓜蛋白酶造成骨关节炎的病理模型,以独活寄生汤浓缩液喂食饲养,于治疗后1、3、5 周分别抽取关节液,采用双抗体夹心酶联免疫吸附法,分别测定兔膝关节液中IL-1及TNF 表达水平。

Chondromalacia causes pain behind the knee, which gets worse when bending, stretching or putting excess pressure on the knee joint. You may also feel, and even hear, a grinding sensation in the knee.

软骨软化症的原因疼痛背后的膝关节,这进一步恶化时,弯曲,伸展或把过剩的压力,膝关节,你可能也觉得,甚至听到,磨削轰动,在膝关节

Objective To study the relationship between IL-1,MMP-13and pathogenesis of knee osˉteoarthrosis.Methods IL-1and MMP-13were measured concurrently in synovial fluid samples from23patients with mild OA,28patients with severe OA and6patients with disciform meniscus.The determinations of positive rate of cells in genual synovium with IL-1and MMP-13were carried out using immunohistochemical techonology.

目的 探讨白细胞介素-1(IL-1)、基质金属蛋白酶-13(MMP-13)在膝关节骨性关节炎发病中的作用方法提取23例OA病变轻微患者、28例OA病变严重患者、6例对照者的滑膜组织及关节液,采用免疫组织化学方法检测膝关节滑膜组织中IL-1、MMP-13的阳性细胞率及通过夹心ELISA法测定膝关节滑液中IL-1、MMP-13含量。

By the two steps, distract and correct the knee flexion at 0 degree to form knee joint with caput fibulae and lower femur and to fit the lower limb brace which can stahilize the knee joint after the llizarov apparatus is disassembled.

结论膝关节牵伸技术,可有效的矫正先天性胫骨缺如伴发的屈膝畸形,安装带膝关节铰链的牵伸器,可将腓骨头与股骨下端控制于中直位,在长期生理性行走应力的刺激下,腓骨发生了胫骨样的变化,可发育成具有类似膝关节形态的结构,整个患肢由于正常的行走使用而得到良好发育。

There is a kind of special protein in synovial fluid of patient's knee joint with osteoarthritis.

膝关节骨性关节炎患者的膝关节滑液中产生了特异性的蛋白质,这种蛋白质在健康人的膝关节滑液中不存在。

METHODS: We selected 110 incident tibiofemoral OA case knees (76 subjects) and 356 random control knees (178 subjects) from among participants in the Framingham Osteoarthritis Study.

从弗雷明汉骨性关节炎研究中心的参与者中选择110个膝关节骨性关节炎的膝关节(76例受试者)和356个随即对照的膝关节(178例受试者)。

It has been well documented that the fibular collateral ligament is the primary varus stabilizer of the knee.8,10 Consequently, isolated FCL injuries can elicit abnormal varus knee instability that can lead to functional limitations, a varus thrust gait pattern, and the potential development of medial meniscal tears or medial compartment arthritis over time due to the increased compressive forces at the medial tibiofemoral compartment.16,23,30 In addition, it has been demonstrated that varus instability, primarily due to a deficient FCL from an untreated posterolateral knee injury, causes a significant increase in force on both anterior cruciate and posterior cruciate ligament reconstruction grafts.11,21,22 Therefore, a reconstruction technique to address nonrepairable acute or chronic isolated FCL tears is important to address these pathologic abnormalities.

已经证实腓侧副韧带是防止膝关节内翻的主要稳定结构[8,10]。因此,FCL离断伤可以引起异常的膝关节内翻不稳定,从而导致功能受限、膝内摆步态和潜在发展为内侧半月板撕裂或由于在增加胫股关节间隙的压力会随时间推移发生内侧间室关节炎[16, 23, 30]。此外,已经证实了主要由膝关节后外侧损伤后未经治疗导致FCL功能缺陷引起的膝内翻不稳可以引起前交叉韧带和后交叉韧带重建移植物受力明显[11,21,22]。因此,认为不可修复的急性或慢性FCL离断撕裂伤的重建技术对这些病理异常非常重要。

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