膝

Kneel down on ground, and face up to the above.

双膝跪在地上，我的脸朝向天空。

OBJECTIVE: To investigate effect of osteoarthritis kneepad by observing cartilage tissue morphology of experimental knee osteoarthritis.

目的：通过观察兔膝骨性关节炎关节软骨组织的病理变化，探讨治疗型关节炎护膝的治疗作用。

BACKGROUND: Treatment arthritis kneepad can dredge meridians and activate collaterals as well as promote qi and blood circulation. It has been proven to be an effective medical instrument to prevent osteoarthritis.

背景：治疗型关节炎护膝具有通经活络、疏导瘀滞、行气活血的作用，已证实是防治膝骨性关节炎行之有效的医疗仪器。

Objective To develop an OA kneepad and explore its mechanism and efficacy on the prevention and treatment of osteoarthritis of the knee through observing the effects of OA kneepad on cytokines, matrix-dissolution, hyaluronic acid, oxygen free radical metabolism, articular cartilage micro-structural changes, cell proliferation and apoptosis.

目的 研制OA护膝，并通过观察OA护膝对骨性关节炎细胞因子、基质溶解素、透明质酸、氧自由基代谢、关节软骨宏微观结构变化和细胞增殖、凋亡的影响，探讨其防治膝骨性关节炎的机制及疗效。

By using low-frequency dynamic frequency density wave, the OA kneepad could regulate many aspects of pathological process of knee OA including: inhibition of biological effects of cytokine, MMP-3, HA, oxygen free radicals and NO; enhancing the biological activity of SOD; up-regulating the mRNA expression of Bcl-2 as well as down-regulating the mRNA expression of P53, thereby to inhibit the apoptosis of cartilage cells and delay the cartilage degeneration of the macro-morphology, cartilage cells and cartilage matrix.

OA护膝采用低频温热动态变频疏密波，针对膝OA病理过程中的多个环节进行调节，能有效抑制细胞因子、MMP－3、HA、氧自由基、NO的生物学效应，增强SOD的生物学活性，提高关节软骨细胞Bcl-2mRNA表达，减弱软骨细胞P53mRNA表达，从而抑制软骨细胞凋亡，延缓膝关节软骨宏观形态、软骨细胞及软骨基质的退变。

Results:(1) After three course of therapy, two methods all can improve KOA clinical symtoms.

结果：(1)治疗前、后两组症状积分比较，两组治疗方法均能使膝骨性关节炎患者临床症状积分降低。

The prescription of gu yan is effective on treating KOA,and is worth of further study.

"骨炎方"具有较好的抗炎、消肿、镇痛的作用，在临床"骨炎方"治疗膝OA是有效的，值得深入研究。

This indicates that acupuncture with warmed needle has better effect for KOA.

表明温针灸对膝骨性关节炎治疗有较好的疗效。

The prescription of gu yan was used to treat KOA by tutor for more than 20 years. But the clinical effect has not been sumed up by now with system.

他20多年来使用的"骨炎方"在治疗膝OA方面疗效满意，但未进行系统归纳总结。

Methods Forty KOA cases were divided into two groups: treatment group in which 20 cases were treated by electroacupuncture and control group in which another 20 cases were treated by Tuina,with a course of one month.

方法将40例膝骨性关节炎患者随机分为两组，分别采用电针和推拿手法治疗1个月。

The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应，而且减少跟风的可能性。