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In this review data on the use of rituximab is presented from 92 studies involving 1197 patients with the following diseases: systemic lupus erythematosus, idiopathic thrombocytopenic purpura, anti-neutrophil cytoplasmic antibody associated vasculitis, Grave's disease, autoimmune hemolytic anemia, pemphigus vulgaris, hemophilia A, cold agglutinin disease, Sjogren's syndrome, graft vs. host disease, thrombotic thrombocytopenic purpura, cryoglobulinemia, IgM mediated neuropathy, multiple sclerosis, neuromyelitis optica, idiopathic membranous nephropathy, dermatomyositis, and opsoclonus myoclonus.

本综述资料总结了92项共1197例患者应用利妥昔的研究,包括系统性红斑狼疮、特发性血栓性血小板减少性紫癜,抗中性粒细胞抗体相关性血管炎、甲状腺功能亢进、自身免疫性溶血性贫血、寻常型天疱疮、甲型血友病、冷凝集素病、干燥综合征、移植抗宿主疾病、血栓性血小板减少性紫癜、IgM介导性神经病、多发性硬化、视神经脊髓炎、特发性膜性肾病、皮肌炎和眼肌阵挛性肌阵挛。

Results The model showed serious edema, proteinuria, hypoproteinemia, and hyperlipidemia. Podocytes were swollen and mesangial cells developed mild hyperplasia at the end of the fourth week. The nephric tubule atrophied at the end of the eighth week accompanied with adhesion between glomeruli and Bowman's capsule. Glomeruli sclerosis of mild or medium degree was observed at the end of the twelfth week with obvious lymphocyte infiltration in the renal interstitium as well as the formation of collagen fibers.

结果 该模型表现为严重水肿、大量蛋白尿、低蛋白血症和高脂血症;病理学检查显示,4周末肾小球足细胞肿胀,系膜细胞轻度增生;8周末有球囊粘连,肾小管上皮细胞萎缩;12周末部分肾小球节段性轻、中度硬化,间质内有明显灶性淋巴细胞浸润,并有轻度纤维化。

Results: The expression of CTGF protein and CTGF mRNA in the nomal and sham operation group is low in the intracytoplasm of Mesangial cells, renaltubular epithelial cells and renal interstitial cells. Compare with sham operation group, the expression of CTGF protein and CTGF mRNA as yellow particulate in the mode group was markedly increased, and the fibrosis of nephridial tissue is obvious. Panaxnotoginseng could significantly decrease the expression of CTGF protein and CTGF mRNA(P.05), and there was no significant difference between Panaxnotoginseng treatment group and Benazepril treatment group.

结果:正常组及假手术组肾小球系膜细胞、肾小管上皮细胞以及肾间质细胞胞浆内有少量CTGF蛋白及其mRNA的黄色颗粒状阳性反应物,模型组上述部位的CTGF蛋白及其mRNA呈强阳性表达,三七总皂苷组上述指标表达较模型组显著减少,有统计学差异(P.05),与阳性药物组比较差异不显著。

I don't think this is clear cell meningioma, chordoma, central neurocytoma, hemangioblastoma, oligodendroglioma, ependymoma or DNET.

我不考虑透明细胞型脑膜瘤、脊索瘤、中枢神经细胞瘤、血管母细胞瘤、少突胶质细胞瘤、室管膜瘤或胚胎发育障碍的神经上皮肿瘤。

Microscopically,tumor showed an invasive growth and nodulous arrangement and was made up of two kinds of cells,relativepart...

免疫组化示:上皮膜抗原,细胞角蛋白,波形蛋白均强阳性,S100,CD34弱阳性,CD20、CD3核可疑阳性,其余多项免疫组化结果均呈阴性。

Pleomorphic/nontolerated VTs required electroanatomic and noncontact mapping in 48 and 22 patients, respectively, and percutaneous cardiopulmonary support in 10 patients.

在多形性或不能耐受的VT患者中,48例患者进行电解剖标测,22例患者行非接触标测,10力患者接受经皮心肺支持,10例患者行心外膜途径消融。

Pleomorphic/nontolerated VTs required electroanatomic and noncontact mapping in 48 and 22 patients, respectively, and percutaneous cardiopulmonary support in 10 patients. An epicardial approach was used in 10 patients.

在多形性或不能耐受的VT患者中,48例患者进行电解剖标测,22例患者行非接触标测,10力患者接受经皮心肺支持,10例患者行心外膜途径消融。

The expression of F1ATPase-α on the pericellular membrane of A549 cells was observed by immunofluorescence.

3用免疫荧光法检测F1ATPase-α在正常支气管上皮细胞与A549细胞胞膜中的表达。

Results In cystitis glandularis tissue AQP1 mainly expressed in the endothelial cells of micrangium,the immunohistochemical positive exponent was 35.947;AQP2 expressed in the cell membrane and periplasm of the mucosa epithelial cells,the immunohistochemical positive exponent was 34.644;and AQP3 did not express.

结果:在腺性膀胱炎组织中AQP1主要表达在微血管内皮细胞,免疫组化阳性指数35.947;AQP2主要表达在炎性膀胱黏膜上皮细胞的胞膜及胞质内,免疫组化阳性指数34.644;AQP3则呈阴性表达。

Seed vertical or horizontal, orbicular; testa membranous or subleathery; embryo spiral; perisperm absent.

种子垂直或水平,球状;种皮膜的或近革质;胚螺旋形;外胚乳无。

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