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Largely unstructured in solution, linear peptides fold into an amphipathic helix upon binding and insert into the target membrane, leading to breakdown of the transmembranal potential and of ion gradients, thus causing leakage of cell contents, resulting finally in cell death.

大多数的抗菌胜肽在水溶液中是呈现松散的结构,但和目标微生物作用时会褶叠形成双性螺旋的结构并插入其膜内,导致破坏膜内外的电位及离子梯度,造成细胞的泄漏,最后导致细胞死亡。

To make it clear, using multilaser flow cytometry, molecular biologic technology and laser confocal microscope scan technology, we fixed eyes on mitochondrial permeability transition pores, mitochondrial transmembrane potential and caspases-3 (cysteinyl aspartate-specific proteinases) which are playing key roles of mitochondria. Meanwhile, the research also discussed the characteristics of Δψm of cells in cut specimenfrom esophageal carcinoma, adjacent tissue of esophageal carcinoma and the normal esophageal tissue.

为探讨食管癌细胞凋亡过程中线粒体所起的具体作用,本课题采用流式细胞检测、分子生物学和激光共聚焦扫描技术等手段,研究了食管癌细胞凋亡中,线粒体所起关键作用的环节—线粒体通透性转变孔(Mitochondrion Permeability Transition Pore,MPTP)、线粒体跨膜电位ΔΨm和线粒体释放反应中的Caspase-3(Cysteine protease-3);同时研究了食管癌手术切除标本中癌灶、癌旁和切端三处组织的细胞线粒体跨膜电位的特性。

In the present work, SDS-PAGE and light scattering method were used to evidence the 〓 and 〓 induced intramembrane aggregation of proteins. The aggregation was found mainly due to the binding of lanthanides to membrane proteins via noncovalent bonding.

本文用SDS-PAGE和光散射方法证明了由〓和〓可引起膜蛋白的聚集,这种聚集主要是由稀土离子以非共价键的与膜蛋白直接结合引起,也有少量以形成二硫键为特征的氧化性交联。

To evaluate the diversity of immunogenicity of IROMPs, OMPs and whole-cell bacterin of leporid P. multocida, and evaluate their cross protection in mouse model.

本试验以小鼠为动物模型,比较了兔多杀性巴氏杆菌铁调节外膜蛋白的免疫原性及分析交叉免疫保护效果。

Objective To evaluate the efficacy and side effects of mycophenolate mofetil in the treatment of idiopathic membranous nephropathy.

目的 评价霉酚酸酯治疗特发性膜性肾病的临床疗效和不良反应。

Treatment with exogenous Spermine could enhance the increase in enzyme activity and delay the increase in permeability of plasma membrane and MDA content.

外源Spm可以提高水分胁迫下SOD、CAT和POD活性的上升幅度,减少膜脂过氧化产物MDA的积累和叶片质膜相对透性的上升幅度。

The basis ingredient of crude lacquer is urushiol that has excellent corrosion resistance and heat resistance.

其主要成分漆酚成膜性好,具有良好的耐腐蚀性、耐热性。

Biology A membranous covering or part, as that on the developing fruiting body of certain mushrooms; a velum.

菌幕,缘膜:一种膜性覆盖层或其中的部分,如在特定蘑菇的正在发展中的子实体上;菌幕

Objective: In the sera of most bullous pemphigoid patients, there are auto-antibodies to the basement membrane zone, that fixed on lamella lucida of BMZ was found by immune-electronic microscope, suggesting the disease is a autoimmune disease.

目的:大疱性类天疱疮(bullous pemphigoid,BP)多数患者的血清中存在抗基底膜带成分的自身抗体,免疫电镜显示这种抗体结合在基底膜带的透明板,因此本病为一种自身免疫病。

The LB films formation and the orientation of TSPP LB films of 5, 10, 15-tn (p-chlorphenyl)-20-m- oxy (a-steanic acid) phenylporphyrin were studied.

研究了具有双亲性的5,10,15-三对氯苯基-20-邻苯基卟啉在气-液界面上的成膜性能,制备了不同层数的TSPP LB膜。

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