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Presynaptically bound opiates may inhibit Ca2+ channels, activate inwardly directed K+ pumps, or inhibit the production of adenyl cyclase.

突触前结合阿片制剂可以抑制钙通道,激火内部的钾泵,或抑制腺苷酸环化酶的生成。

Methods The orthotopic liver transplantation in the rat was made by threecuffs. OLT rats were divided into two groups: OLT controland IP. The hepatic function and hepatic adenylic acids were determined by autochemical analysor and high performance liquid chromatography respectively.

方法制备三袖套大鼠同种异体原位肝移植模型,将其分为OLT对照组和IP组,用自动生化分析仪检测血中ALT、AST和LDH,用高压液相色谱仪测定移植肝组织中腺苷酸含量的变化。

Mehtods Thirty male SpragueDawley rats were randomly divided into acute stress,chronic stress and control group(each n=10),acute and chronic stress models were made with forced swimming and empty bottle stimulation separately,and frequency of getting into central grille, detention time , outer grille numbers,modifying numbers and dejecture grain number were observed with openfield experimental box;expressions of neuropeptide Y and adenylcyclase in prefrontal lobe cortex, hippocampus CA3,striatum of the groups were observed using the immunohistochemistry method and correlation analyses conducted.

将30只雄性SD大鼠随机分为急性应激组、慢性应激组和正常对照组,每组10只,用强迫游泳和空瓶刺激分别制作急性和慢性应激模型,采用开野实验箱观察各组大鼠进入中央格次数、停留时间、外周格子数、修饰次数、粪便粒数;采用免疫组织化学方法检测各组大鼠神经肽Y、腺苷酸环化酶在前额叶皮质,海马CA3区,纹状体的表达水平,并进行相关分析。

Mehtods Thirty male Sprague??Dawley rats were randomly divided into acute stress,chronic stress and control group(each n=10),acute and chronic stress models were made with forced swimming and empty bottle stimulation separately,and frequency of getting into central grille, detention time , outer grille numbers,modifying numbers and dejecture grain number were observed with open??field experimental box;expressions of neuropeptide Y and adenylcyclase in prefrontal lobe cortex, hippocampus CA3,striatum of the groups were observed using the immunohistochemistry method and correlation analyses conducted.

将30只雄性SD大鼠随机分为急性应激组、慢性应激组和正常对照组,每组10只,用强迫游泳和空瓶刺激分别制作急性和慢性应激模型,采用开野实验箱观察各组大鼠进入中央格次数、停留时间、外周格子数、修饰次数、粪便粒数;采用免疫组织化学方法检测各组大鼠神经肽Y、腺苷酸环化酶在前额叶皮质,海马CA3区,纹状体的表达水平,并进行相关分析。

Objective To explore the effects of acute and chronic stress on behavior and expression of neuropeptide Y and adenylcyclase in rats′ different encephalic region.

目的 探讨急、慢性应激对大鼠行为及不同脑区神经肽Y、腺苷酸环化酶表达的影响。

Pituitary adenylate cyclase activating polypeptide is a widely expressed neuropeptide that has been involved in nerve regeneration, neurone survival and nociception.

垂体腺苷酸环化酶激活多肽是一个广泛表达的神经肽,涉及神经再生,神经生存和伤害感受。

BACKGROUND: Recent reports have identified a role for cyclic adenosine monophosphate transduction in nociceptive processing.

背景:近来的研究表明,环腺苷酸转导在感受伤害性处理中有一定作用。

Akt,AMPK and ERK proteins were detected by western blot analysis,and the distribution of GLUT4 in these skeletal muscles was observed by immunofluorescence. Results The expression of GLUT4 on the cell membrane was significantly higher in the electrically stimulated groups than in the unstimulated groups.

用Western Blot法测定骨骼肌中蛋白激酶B(protein kinase B,PKB/Akt)、腺苷酸激活的蛋白激酶、细胞外信号调节激酶的表达和活性变化,用免疫荧光方法观察GLUT4在细胞膜及细胞内膜的分布。

Some pre-mRNA are cleaved near the 3'end but no poly tail is added.

有一些mRNA前体也在3'端附近被切开,但却没有多聚腺苷酸尾。

Expression of human β-arrestin 1 attenuated κ andδ opioid receptor subtype-mediated G protein activation and inhibition of cAMP production, while did not affect the concentration- effect relationship ofμ-agonist 〓-enkephalin in the same signalings.

arrestin 1的表达明显减弱了κ型,δ型阿片受体亚型所介导的G蛋白的激活和腺苷酸环化酶活性的抑制,但是却不影响μ型阿片受体亚型特异性激动剂〓-enkephalin刺激引起的浓度效应曲线。

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The concept of equivalent rotationally rigidity is offered and the formula of rotationally rigidity is obtained.

主要做了如下几个方面的工作:对伸臂位于顶部的单层框架—筒体模型进行分析,提出了等效转动约束的概念和转动约束刚度的表达式。

Male cats normally do not need aftercare with the exception of the night after the anesthetic.

男猫通常不需要善后除了晚上的麻醉。

Its advantage is that it can be used in smaller units.

其优点在于可以在较小的单位中应用。