腺苷酸

Adenosine is a signaling molecule that is elevated in the lungs of patients with asthma and COPD.

腺苷酸是一种细胞信号分子，在哮喘和COPD患者中腺苷酸水平升高。

Caffeine - A derivative of coffee, is an efficient arouser of central nervous system capable to drive away fatigue, and improve renal circulation. Its stimulation on the cerebral cortex activates Neurotransmitter receptors in the cell membrane; the adenylyl cyclaseactivated on the other surface of the cell catalyzes Adenosine Triphosphate, forming Cyclic adenosine monophosphate, and thus set off series of bio-chemical reactions, like increase of passionate feel, prompt recovery from fatigue after working etc..

咖啡因—由于咖啡本身具有兴奋神经中枢，消除疲劳，增加肾脏血流量的作用，通过对大脑皮层的刺激，使神经递质作用于细胞膜受体，激活了膜另一侧的腺苷酸环化酶，被激活的腺苷酸环化酶催化三磷酸腺苷环化酶，被激活的腺苷酸环化酶催化三磷酸腺苷形成环磷酸腺苷，从而引起一系列生化反应，如增加愉快感和消除事后疲劳等。

Objective To study the effects of heroin on adenosine deaminase in small inteseine and plasma uric acid content in rats.

目的：通过检测大鼠小肠腺苷脱氨酶和血浆尿酸的含量探讨海洛因对大鼠小肠腺苷酸分解代谢的影响。

According to the complex structure of AdSS and its substrate IMP as well as the optimized stable conformation of natural inhibitors, the interaction mode between AdSS and its inhibitors was studied with molecular docking, mechanical optimization and molecular dynamics simulation methods. These results show that the phosphate group and the hydantoin ring of the inhibitors form the pharmacophore model.

基于腺苷酸琥珀酸合成酶与其底物肌苷单磷酸复合物的晶体结构以及获得的天然抑制剂衍生物稳定构象，利用分子对接、分子力学优化及常温分子动力学模拟对AdSS酶与天然抑制剂及其衍生物的相互作用复合物结构进行理论预测。

Cyclic AMP (cAMP; adenosine-3',5'-monophosphate) A form of adenosine monophosphate formed from ATP in a reaction catalyzed by the enzyme adenyl cyclase.

环腺苷酸：腺苷酸的一种类型。是由 ATP 在腺苷酸环化酶的催化下生成的结构。

After thecomplete genome extraction of the strain was performed, the genomic DNA was partiallydigested by restriction enzyme Sau3AⅠ, the DNA fragments from 1 to 5Kb was clonedinto prokaryote expression vector pET-28a-c, and transformed host bacteria. The resultsshowed that we succeeded in constructing the gene expression library of haemophilusparasuis serovar 5, which is fundamental for the study of advanced gene screening. Inaddition, primer design was performed based on haemophilus influenzae in this study. In addition, PCR was performed by using genomic DNA of haemophilus parasuisserovar 5 as the template. The results demonstrated that we obtained two neo-gene:23SrRNA gene(conserved gene belonging to the large-subunit of ribosome) and adenylatecyclase gene(encodes adenylate cyclase and participates in converting adenyl nucleosidetriphosphate to cyclic adenosine3",5"-monophosphate). Furthermore, the phylogeneticanalyses between the species was performed, and neighbor-joining tree was constructedbased on comparison of 23S rRNA gene sequences, so it was illuminated betweenHaemophilus parasuis and other species in molecular evolution relationship.

选择我国流行优势菌株副猪嗜血杆菌血清5型地方株为研究对象，提取细菌基因组DNA，用限制性内切酶Sau3AⅠ对基因组DNA进行部分酶切，回收大小为1～5Kb的DNA片段，将其连接入原核表达载体pET-28a-c，最后转化宿主菌，结果成功地构建了基因表达文库，为后续的基因筛选工作奠定基础；另外，本研究选择嗜血杆菌属的流感嗜血杆菌为参考对象进行引物的设计，以副猪嗜血杆菌血清5型地方菌株的基因组DNA为模板，进行PCR扩增反应，结果表明成功地获得两个新基因：23S rRNA基因(存在于核糖体大亚基中的保守性基因)和腺苷酸环化酶基因(负责将腺嘌呤核苷三磷酸转变为环腺苷酸)，并进一步做了不同物种之间的分子系统发育分析，构建了基于23S rRNA基因的邻接法系统发育树，阐明了副猪嗜血杆菌与其它菌种的分子进化关系。

After the establishment of irritable bowel syndrome model, the energy charge of adenosine triphosphate and the ratio of ATP to the total amount of adenylic acid pool in colonic epithelial cells at the ileocecum with better colonization were determined by high performance liquid chromatography.

在建立了IBS动物模型基础上，采用高效液相色谱法对CGC定植较多的回盲部肠黏膜上皮细胞的腺苷酸能荷及ATP与腺苷酸库比值进行测定，以反映细胞活性状态。

Methods Using HIRI model in tabbits,animals were randomly divided into four groups (n=10 in each),HIR group,HIR+ LGT group,HIR+ Pro group and HIR+ LGT+ Pro group,the contents of adenosine triphosphate,adenosine diphosphate,adenosine monophosphate,total adenylic acid numberand energy charge in the liver tissue were measured at 45 minutes after reperfusion, respectively.

复制肝缺血-再灌注损伤模型，随机将40只实验兔分为肝缺血-再灌注组、肝缺血-再灌注＋LGT治疗组、肝缺血-再灌注＋PRO治疗组和肝缺血-再灌注＋LGT＋PRO治疗组。在再灌注45 min时，分别观察肝组织内三磷酸腺苷、二磷酸腺苷、一磷酸腺苷含量、总腺苷酸量、能荷及肝细胞形态学的变化。

Wenxin capsule can promote endolethial cells releasing CO and synthesing 〓, enhance activity of HO, induce angiectasis through activating guanylic cyclase and adenglate cyclate of intracellar of vessel smooth muscle cell to enhance content of intracellar cGMP and AMP. 3. Wenxin capsule can inhibit releasing of platelet activiting factor 〓 which inhibit platelet aggregation and have antithrombosis function. 4. Wenxin capsule can promote activity of t-PA, reduce activity of PAI-1, strengthen fibrinolytic function, therefore inhibit fibrin disposition. 5. Wenxin capsule can inhibit synthesis of smooth muscle cellular DNA. Its function don't kill it directly but prevent transformation from period Go to peried S. 6. Wenxin capsule is an effective prescription of anti-coronary atherosclerosis atherosis. The results of image pattern analysis tastifies that area of lipid plaque in treating group reduce 54% and 58% in contrast with that in control group. The results of light, electro- microscopy show that structure of endolethial cell and smooth muscle cell in treating group is more integral than that in control group.

其作用机制之一是由于该药具有良好的调脂降脂作用，其不仅能明显降低血清LDL-c及升高HDL-c含量，且能有效阻止TC沉积于血管壁，从而保护内皮细胞结构完整；此外，温心胶囊尚具有明显的抗氧化作用，该药不仅能明显降低血浆LPO含量，且能提高SOD活性，同时其对血红素在细胞内代谢的调节作用也参与了抗氧化过程。2 温心胶囊能明显促进内皮细胞释放CO及合成〓，提高HO活性，通过激活血管平滑肌细胞内鸟苷酸环化酶及腺苷酸环化酶引起细胞内cGMP、AMP浓度增加而引起血管舒张。3 温心胶囊能明显抑制血小板激活因子〓的释放，从而抑制血小板聚集，抗血栓形成。4 温心胶囊能明显提高t-PA活性，降低PAI-1活性，增强纤溶功能，从而抑制纤维蛋白沉积。5 温心胶囊能明显抑制平滑肌细胞DNA合成，其抑制作用不是直接杀伤抑制，而是阻止细胞由Go期向S期转化。6 温心胶囊是抗冠状动脉粥样硬化的有效制剂，图象分析结果证实，该药治疗组脂斑面积比对照组缩小了54％和58％，光电镜结果显示内皮细胞及平滑肌细胞结构较为完整。

The results showed that most of the microbes could be inactivated for the ultra high pressure treatment, the accumulation of total volatile basic nitrogen was restrained, and the change of pH value was delayed. The shelf life of white shrimp was prolonged with the enhancement of high pressure. High pressure treatment could make fresh shrimp with boiled flavor in some degree. Trements of 400 Mpa and 600 MPa aggravated blackening. However, melanotic reaction was not observed during the whole storage of shrimp treated by 700 MPa. High pressure could change the metabolizing of ATP and its metabolites, but did not impact the metabolic pathway of AMP decomposition.

结果表明：超高压处理可以有效地杀灭南美白对虾中绝大多数微生物，抑制贮藏过程中挥发性盐基氮的积累，延缓pH值的变化，从而延长南美白对虾的货架期，且处理压力越高延长效果越显著；超高压处理会给鲜虾带来不同程度上的煮熟虾的风味；400 MPa和600 MPa处理使虾在冷藏过程的黑变提前，而700 MPa处理可以完全抑制南美白对虾黑变现象的发生；超高压能够改变腺苷三磷酸及其代谢产物的代谢情况，但不影响腺苷酸的代谢途径。

It has been put forward that there exists single Ball point and double Ball points on the symmetrical connecting-rod curves of equilateral mechanisms.

从鲍尔点的形成原理出发，分析对称连杆曲线上鲍尔点的产生条件，提出等边机构的对称连杆曲线上有单鲍尔点和双鲍尔点。

The factory affiliated to the Group primarily manufactures multiple-purpose pincers, baking kits, knives, scissors, kitchenware, gardening tools and beauty care kits as well as other hardware tools, the annual production value of which reaches US$ 30 million dollars.

集团所属工厂主要生产多用钳、烤具、刀具、剪刀、厨具、花园工具、美容套等五金产品，年生产总值3000万美元，产品价廉物美、选料上乘、质量保证，深受国内外客户的青睐