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The vasodilating effect of IV adenosine was immediate in onset and ultrashort in duration.

静脉应用腺苷的扩血管效应即刻产生且持续时间极短。

Remifentanil had a rapid onset and short duration of action, and probably showed signs of tolerance development, whereas the antinocieptive effect of adenosine was slow in onset and long-lasting, despite its ultrashort plasma half-life and the immediate on-off profiles of its vasodilating effect.

瑞太尼起效迅速且作用时间短,很可能显示了耐受性的发展,而腺苷的伤害感受效应起效缓慢且持续时间长,但血浆衰期极短,具有即刻开-关特性的扩血管效应。

RESULTS: Intracerebroventricular injection of SAM produced a significant decrease in blood pressure and heart rate of the anesthetized rats.

结果:侧脑室注射S-腺苷蛋氨酸能够显著降低麻醉大鼠的血压,减慢大鼠的心率。

Objective To observe the curative effect on asphyxiated newborn with heart muscle damage curing by adenosine combined with conventional drugs.

目的 观察联合腺苷治疗对新生儿窒息并心肌损害的疗效影响。

Some pre-mRNA are cleaved near the 3'end but no poly tail is added.

有一些mRNA前体也在3'端附近被切开,但却没有多聚腺苷酸尾。

It was noticed that Majority (13/25) of C DRG cells and minority of A DRG cells were depolarized by bath application of morphine at the dose of 0.1mmol/L.

在新生大鼠脊髓—背根神经节标本上细胞内记录背根神经节两类细胞的膜电位,观察吗啡的作用和腺苷及其受体阻断剂茶硷对其的影响。

These results suppose that niacin prorates reverse cholesterol transport by increasing ABCG5 and CYP7α expression which is stimulated by LXRα.

烟酸可能通过上调体内肝X受体α,从而刺激三磷酸腺苷结合盒转运体G5、胆固醇7α羟化酶表达来发挥促进小鼠体内胆固醇逆转运作用。

The optimum condition for separating and purifying SAM was using the solution at pH of 5.0 containing 3.0 g SAM per liter at the flow velocity of 6 L/h through the ion-exchange column (φ50 mm×1500 mm)filled with D152 resin. Impurities were removed first by eluting the column with double-distilled water and acetic acid, and then with 9 L to 15 L of sulfuric acid of 50 mmol/L concentration at the flow velocity of 6 L/h.

论文对SAM的性质、药理作用以及当前国际上关于SAM的研究进展进行了较为详尽的综述,并在此基础上确立了研究内容,取得了如下成果: 1利用本实验室构建的基因工程菌JM71发酵生产S-腺苷-L-蛋氨酸,在50 L发酵罐中发酵6天后,SAM终产量达到6 g/L发酵液。

The traditional method to determine cyano cobalamin by HPLC cannot be used for rapid determination of vitamin B 12 in fermentation broth.

文中探索了一种不经氰化物转化而直接使用HPLC测定发酵液中维生素B12 (包括羟基钴胺素、脱氧腺苷钴胺素和甲基钴胺素)的检测方法。

IL-1β decreased ATP content and KBR in the hepatocytes in both groups, and such decrements were more significant in PH group.

IL-1β能够降低两组肝细胞的5'-三磷酸腺苷含量和酮体比率,PH组降低程度大于对照组。

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