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Results There were 74 cases of squamous carcinoma,5 cases of adenocarcinoma and one case of adenosquamous carcinoma.

结果 鳞癌74例、腺癌5例、腺鳞癌1例。

Results\ Of 11 cases: 6 cases were adenoid cystic carcinoma, 4 cases were squamous carcinoma, and 1 case was adenocarcinoma.

结果 11 例中腺样囊性癌6 例,鳞状细胞癌4 例,腺癌1 例。

I will apply Immumohistochemical method to detect proliferating cell nuclear antigen expression of lung adenocarcinoma histiocyte inpatients, and I will study apoptosis of lung adenocarcinoma cells by TUNEL method; calculate PCNALI and ALI; compare and analysis PCNALI and ALI of different patients with different clinic features simultaneously .

例肺腺癌组织中增殖细胞核抗原的表达,同时通过TUNEL法检测肺腺癌细胞凋亡,计算PCNA增殖指数和细胞凋亡指数,对不同临床特点肺腺癌患者的PCNALI、ALI进行比较分析。

Barium meal roentgenography showed evidence of a lesion in the esophagus preope-ratively in each case.

贲门部病变中,8例为腺癌或腺鳞癌,1例为食管与贲门的双原发鳞状细胞癌。

Mucinous adenocarcinoma is a rare variant of acinar adenocarcinoma of the prostate.

粘液腺癌是一种罕见的前列腺腺泡状腺癌的变型。

These cancer cells might histogenetically be related to the transitional or metaplastic epithelium of prostate according to morphological analysis,(2) Mucinous adenocarcinoma, Xanthomatous carcinoma, ductal carcinoma, medullary carcinoma, endometrioid carcinoma, papillary carcinoma and signet-ring cell carcinoma were positive for PSA and 35βH11, these carcinomas might histogenetically be related to prostatic secretory epithelium,(3) Prostatic carcinoid showed positive to PSA, 35βH11, NSE and CgA, corresponded with endocrine cell originator,(4) Small cell carcinoma were negative for PSA, 35βH11, NSE and CgA, whether or not it originates from endocrine cells, storage cells or basal cell of prostate had yet to be proved,(5) 34βE12 marking was negative in cancerous areas of 27 cases, and the basal cells were absent in PPTC.

从形态分析,这两种癌可能同源于移行上皮或化生上皮:(2)粘液腺癌、黄色瘤样癌、导管癌、髓样癌、宫内膜样癌、乳头状癌及印戒细胞癌均显PSA及35βH11阳性,提示这几种癌可能来源于分泌上皮,(3)类癌对PSA、35βH11、NSE及CgA均显阳性,符合内分泌细胞来源,(4)小细胞癌无PSA、NSE及CgA表达,对c-erbB-2及35βH11显阳性,是否来源于前列腺内分泌细胞、储备细胞或基细胞有待证实,(5)27例癌区均无34βE12表达,提示PPTC中基细胞缺失。

PURPOSE: To investigate the combined effects of adenoviral-mediated p53(Ad-p53) transgene expression and irradiation response in nude mice models of lung adenocarcinoma (A549 and GLC-82).To determine whether wtp53 sensitizes cells to radiation independently of their p53 status and to investigate the interaction mechanism.

目的:本研究筛选了P53基因状态不同的两种人肺腺癌细胞系A549及GLC-82,分别建立裸鼠人肺腺癌移植瘤模型,使用E1复制缺陷型重组腺病毒介导的野生型P53基因瘤内注射治疗,观察其放射增敏作用并探讨其机制,同时比较不同P53基因状态对治疗的影响,为临床开展基因放射治疗提供实验依据。

The investigation of cells of bronchial lavages with lung cancer showed hypermethylation of at least one gene in squamous cell carcinoma, adenocarcinoma, small cell lung cancer and adenosquamous carcinoma is 17/23(73.9%),13/20(65.0%),4/5 and 2/3, respectively.

51例肺癌患者中,支气管灌洗液和上清研究过甲基化结果如下:对灌洗液细胞进行三种基因过甲基化研究诊断鳞癌、腺癌、小细胞癌和腺鳞癌的阳性比例分别为17/23(73.9%),13/20(65.0%),4/5,2/3。

We extracted DNA from bronchial lavages cells and supernatants, and made a quantitative analysis of free DNA from supernatants, then analyzed hypermethylation of three genes in bronchial lavages supernatants and cells. Our objective is to investigate the possibility of bronchial lavages supernatants used in molecular biology diagnosis of lung cancer, and the value of hypermethylation of gene in the diagnosis of primary lung cancer.

本研究选取北京胸部肿瘤结核病医院收治怀疑肺癌患者78例,包括肺癌51例,其中鳞癌23例,腺癌20例,小细胞癌5例,腺鳞癌3例,中心型肺癌27例,周围型肺癌24例,男性32例,女性19例,平均年龄(57.1±13.5)岁,良性病变患者27例,其中肺结核17例,肺炎5例,肺部良性肿瘤5例,男性16例,女性11例,平均年龄(39.5±10.7)岁。

The correlation between Survivin and p53 expression and histological tyes and clinical stages in ovarian carcinoma were analysed.

结果: 1。卵巢癌p53和Survivin蛋白阳性表达率在卵巢癌组织中P53蛋白阳性表达率为54.84%(34/62)与正常对照组比较有显著差异(p<0.01);在浆液性囊腺癌中P53蛋白表达阳性表达率为56.52%(26/46)在黏液性囊腺癌中P53蛋白阳性表达率为57.14%(8/14)两组间无明显差异(p>0.05)。

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