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OBJECTIVE: To study the expression and significance of Ezrin in adenoid cystic carcinoma of salivary gland.

目的:探讨Ezrin在涎腺腺样囊性癌组织中的表达及意义。

Objective To determine the sensitivity of salivary adenoid cystic carcinoma cells to anticancer agents.

目的 检测涎腺腺样囊性癌对抗癌药物的敏感程度。

The most common malignant parotid tumors in children are the following:(1) mucoepidermoid carcinoma,(2) acinic cell carcinoma, and (3) undifferentiated carcinoma.

在儿童最常见的恶性腮腺肿瘤如下:( 1 )黏液表皮样癌,( 2 )腺泡细胞癌,以及( 3 )未分化癌。

The most common malignant parotid tumors in children are the following:(1) mucoepidermoid carcinoma,(2) acinic cell carcinoma,and (3) undifferentiated carcinoma.

在头上 肉瘤最常见的恶性腮腺肿瘤如下:( 1 )黏液表皮样癌,( 2 )腺泡细胞癌,以及( 3 )未分化癌。

AQP 1 has been found associated with nephradenoma, breast cancer, cholangiocellularcarcinoma and hemangioblastoma of CNS.

现已发现AQP1表达于肾腺瘤、乳腺癌、肝脏胆管细胞癌、中枢神经系统的血管母细胞瘤,AQP2表达于肾细胞癌,AQP3的检测有助于肾集合管癌的诊断和鉴别诊断,AQP5可能参与卵巢肿瘤的发生。

Accumulated studies have found that the tumor cells and tumor-associated macrophages in tumor tissues such as ovarian cancer, lung cancer, breast cancer, renal cell carcinoma and adenoid cystic carcinoma overexpress B7-H4 molecules.

越来越多的研究发现,在肿瘤组织如卵巢癌、肺癌、乳腺癌、肾癌和腺样囊性癌等的肿瘤细胞以及肿瘤相关巨噬细胞中异常高表达B7-H4分子。

The suspicion of cancer is increased by the following factors:(1) age (young patients are more susceptible);(2) sex, if the patient is a man (more women have thyroid cancer by a ratio of 2:1, but women have more thyroid disease by a ratio of about 8:1; thus, a man with a nodule should be regarded with greater suspicion);(3) a solitary nodule (multinodular lesions are usually benign unless there is a dominant cold nodule by thyroid scan);(4) a cold nodule on thyroid isotopic scanning (hot nodules are seldom cancerous);(5) a history of radiation exposure to the head, neck, or chest, especially in infancy and childhood (eg, for an enlarged thymus or enlarged tonsils, acne, or lymphoma);(6) radiographic evidence of fine, stippled psammomatous calcification or dense, homogeneous calcification;(7) recent or rapid enlargement; and (8) stony-hard consistency.

下列因素可增加癌的可疑性:(1)年龄;(2)性别,如果病人为男性(女性与男性的甲状腺癌比为2:1,但女性更多的是得甲状腺病,约为8:1,因此,男性有甲状腺结节时应考虑癌的可能性更大);(3)孤立小结(多结节病变一般为良性,除非甲状腺扫描时呈明显的冷结节);(4)甲状腺同位素扫描时发现冷结节;(5)有过头、颈、胸放射接触史,尤其是婴儿和儿童期(例如,因胸腺增大或扁桃体肿大、痤疮或淋巴瘤等);(6)X线片见细、斑点状、沙粒样钙化或致密、匀质钙化;(7)最近增大或快速增大;(8)质地石头样坚硬。

Results There were 19 cases of thymoma, 6 cases of thymolipoma, 1 case of thymic carcinoma.

结果:胸腺瘤19例,胸腺脂肪瘤6例,胸腺鳞癌1例。

Basaloid squamous cell carcinoma of the esophagus is rare, historically confused for adenoid cystic carcinoma, and recently shown to behave similar to conventional, keratinizing esophageal squamous cell carcinoma.

食管基底细胞样鳞状细胞癌罕见,组织学上易与腺样囊性癌相混淆。最近有研究表明,食管BSCC生物学行为类似普通角化型食管鳞状细胞癌。

Methods The expression of Galectin-3 was investigated by immunohistochemistry in the tissures of 50 thyroid cancers (including 32 papillary cancers and 18 follicular cancers), 45 thyroid adenomas and 20 normal thyroids.

运用免疫组织化学方法,检测50例甲状腺癌(其中甲状腺乳头状癌32例,甲状腺滤泡状癌18例)、45例甲状腺腺瘤及20例正常甲状腺组织中Galectin-3的表达。

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