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Also demonstrated the efficiency of biological bypass for the therapy of patient with coronary heart disease by intramyocardial administration of adenoviral vector encoding for human vascular endothelial growth factor 121.

Rosengart小组也在1999年将编码血管内皮生长因子121的复制缺陷型腺病毒载体用于冠心病治疗并获得成功。

In conclusion, intraosseous BMP4 adenoviral gene therapy can improve early implant stability through enhancing peri-implant bone healing.

本研究显示骨内骨形态生成蛋白4腺病毒基因治疗可透过促进植体周围骨愈合而改善植体的早期稳定度。

Objective: To study the treatment of experimental lung metastasis by intratracheal injection of IL-18 gene recombinant adenovirus.

目的:研究气管内应用白细胞介素18(IL-18)重组腺病毒(AdIL-18)对实验性肺转移癌的治疗作用。

Similarly, intravitreous injection of RPE cells infected with adenoviral vectors that overexpress CTGF induced fibrotic PVR.

相似的,玻璃体内注射感染过度表达CTGF的腺病毒的RPE细胞可以促进PVR的纤维化。

Changes in Red Cell Enzyme Activity in Relation to Red Cell Survival in Infancy Antibody Deficiency Syndrome with Increased Gamma1 M(B2M) Globulins and Absent Gamma1 A(B2A) Globulins and Gamma2 Globulins. Needle Biopsy of the Liver in Various Forms of Childhood Tuberculosis Jaundice Associated with Severe Bacterial Infection in Young Infants Effectt of Hypoxia on Newborn Animals Renal Amyloidosis Resulting From a Chronically Infected Burn. Skin Testing of Allergic and Normal Children with Purified Milk Proteins. Pericarditis in Juvenile Rheumatoid Arthritis Cardiac Complication of Diphtheria Adenovirus Complement-fixing Titers from Birth through First Year Congenital Coronary A-V Fistula Narcotic and Methamphetamine Use During Pregnancy Purulent Pericarditis Transfer of Bilirubin-C^4 Across Monkey Placenta Plasma Antidiuretic Hormone in Nephrogenic Diabetes Insipidus Studies of Anabolic Steroids:Ⅰ.

红血球酵素活性度之变化与婴儿红血球生存期之关系 Gamma1 M(B2M)球蛋白增加而无Gamma1 A(B2A)球蛋白与Gamma2球蛋白之抗体缺乏症候羣儿童期各型结核病之肝藏针管活体切片检查幼儿细菌严重感染并发之黄疸缺氧对於新生动物之影响及其与肺玻璃膜病之关系烧伤处慢性感染引起之肾性淀粉样变性以精制奶粉蛋白对过敏症与正常小儿作皮肤试验年幼性类风湿性关节为合并的心包炎白喉之心脏合并症自出生至一岁之腺病毒补体结合滴定度先天性冠状动静脉瘻管怀孕时使用麻醉剂与Methamphetamine之结果化脓性心囊炎胆红素C^14标猴子胎盘之转送肾因性尿崩症患儿之血清抗利尿荷尔蒙之证明同化类固醇之研究Ⅰ。

Methods: The human KDR promoter (-225 bp~+127 bp) was cloned by PCR. Subsequently, a recombinant adenoviral plasmid carrying KDR promoter for the HSV-tk gene was constructed with the AdEasy system. As a control, the plasmid pAdCMV-tk carrying CMV promoter for the HSV-tk gene was also constructed. 293 packaging cells were transfected by both newly-constructed plasmids and the infectious viruses AdKDR-tk and AdCMV-tk were generated. Then the KDR-producing cells and the KDR nonproducing cells (HepG2) were infected with AdKDR-tkand AdCMV-tk, followed by ganciclovir administration.

应用PCR克隆出人KDR基因启动子序列-225bp~+127bp,以AdEasy system为载体,构建携带受KDR启动子或CMV启动子调控tk基因表达的2种重组腺病毒质粒pAdKDR-tk和pAdCMV-tk,在293细胞中包装、扩增后,体外感染表达KDR的脐静脉血管内皮细胞系HUVEC和不表达KDR的肝癌细胞系HepG2,并给予不同浓度的丙氧鸟苷处理,5d后收集存活细胞并计数。

METHODS: The adenovirus-mediated gene transfer was used to overexpress FKBP12.6 in ventricular myocytes of rats with heart failure.

用携带FKBP12.6基因的重组腺病毒Ad。

S short half-life and immunological reaction. To overcome these drawback of protein injection, we choose the gene transfection method to inhibit the overexpression of VEGF in the pannus and observe the inhibition effect of the formation of pannus during the development of rheumatoid arthritis.

为了克服生物制剂关节腔注射疗法半衰期短,局部反应大的缺点,我们采用滑膜组织基因转染的方法,将表达反义VEGF基因的腺病毒载体导入病变的滑膜组织,在基因水平上千预病变滑膜的VEGF过度表达,并探讨其对RA形成的影响。

Chlamydophilophila psittaci MOMP ; recombination ; genetic ; adenoviridae ; neutralization tests ; chicks immunity

衣原体;鹦鹉MOMP ;重组;遗传;腺病毒科;中和试验;雏鸡免疫

Objective To investigate adenoviral vector mediated exogenous gene expression in mouse lun gs and the effect of mIFN-γ transgene expression on allergen-induced pulmonar y eosinophil infiltration in a murine asthmatic model.

目的研究重组复制缺陷腺病毒在小鼠肺内气道上皮细胞中的转基因表达水平及其介导小鼠γ-干扰素的转基因表达对过敏原诱导的小鼠哮喘模型的预防性治疗作用。

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