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Between P14 and P21,CIAPIN1 immunoreaction in the brain,heart and liverbecame much lower. However,between P21 and P28,CIAPIN1 immunoreactionin the heart,brain,liver and skeletal muscle became much lower,while with thekidney development,CIAPIN1 immunoreaction in the kidney became higher. Invarious tissues from adult mouse,CIAPIN1 immunoreaction could be seen incardiac muscle cell,brain,hepatocyte,epithelium of renal tubule,skeletal muscle,lung tissue,gastric mucosa and gland,acinus lienalis.2. Distribution of CIAPIN1 in normal fetal and adult human tissuesTo reveal the possible physiological role of CIAPIN1,we examined theexpression and distribution of CIAPIN1 in fetal and adult human tissues usingimmunohistochemistry. We found that CIAPIN1 was ubiquitously distributed infetal and adult tissues,and was localized in both the cytoplasm and the nucleus.

然而,在3个月大的成年鼠中,CIAPIN1阳性反应物在心、脑、肝和肾小管中的表达强度要低于P28小鼠;但CIAPIN1阳性反应物在成年鼠骨骼肌中较P28小鼠高。2、CIAPIN1蛋白在人5个月胚胎及成人多器官组织内的表达在人5月胚胎多器官组织中,CIAPIN1阳性反应物见于心脏、胆囊单层柱状上皮和粘膜、结肠粘膜、小肠粘膜和绒毛、肝脏、直肠腺体、胃粘膜、肾上腺束状带、甲状腺滤泡、脾索、胸腺小叶间隔、皮肤真皮层和汗腺、睾丸白膜和间质、脑组织内神经元和神经胶质、肺小支气管和肺泡、骨骼肌、肾脏皮髓质和肾小管、子宫内膜、胰腺腺泡和胰岛、卵巢、输卵管粘膜等绝大多数组织细胞。

Results: MR demonstrated capsule wall and papillary solid lesions in one case with cystic and solid lesions of hepatobiliary cystadenoma. Poly cystic form tan if different sine in sew case, capsule wall and septation was thick, part of capsule wall was obviously thickened and nodes form, intrahepatic bile duct was dilated, large poly-antrum cystic keen form structure in one case, capsule wall and septation were smooth, part of capsule wall was uniformly thicken, capsule wall, septation, mural nodus form and solid lesions in three cases wee all slightly hyperintense on T2WI and slightly hypointense on T1WI. Part of cyst fluid was hypointense on T2WI the diameter if tumor ranged from 3.4cm to 13.5cm. Part of capsule wall, septation, solid lesions and mural nodus west obviously enhanced in arterial phase in three cases, the extent of enhancement showed a little degrade in port vein phase, balance phase and delay phase, but dense to liver parenchyma at synchronization.

结果:3例肝内胆管囊腺瘤中1例呈囊实性结构,可见囊壁及乳头状实性肿块;1例为多个大小不等的多房囊状结构,囊壁及分隔光滑,囊壁局部明显增厚,有壁结节,周围见轻度的肝内胆管扩张;1例为巨大的多房囊状结构,囊壁及分隔光滑,局部均匀增厚;3例中的囊壁、分隔、壁结节及实性部分均呈T2WI稍高信号、T1WI稍低信号,囊内液性部分均呈T2WI高信号、T1WI低信号;肿瘤瘤体大小径线范围3.4~13.5cm.3例肝内胆管囊腺瘤中囊壁、分隔、实性肿块和壁结节动脉期均明显强化,门脉期、平衡期及延迟期强化程度略减低,强化程度均高于同期肝实质。

The results suggest that EGFR overexpression, nm23-H1 low expression and negative correlation of their expression may be one of the causes of PTC?s biological feature of lymph node metastasis; serail tests of EGFR, nm23-H1 could be used as the markers to evaluate lymph node metastasis of PTC.

甲状腺乳头状腺癌EGFR的过表达,nm23-H1的低表达,二者表达的失平衡是其易于淋巴结转移的原因之一,EGFR,nm23-H1联用可作为甲状腺乳头状腺癌淋巴结转移的评价指标。

Atypical polypoid adenomyoma is an uncommon polypoid lesion of the uterus that exhibits glandular and squamous epithelial cell proliferation with varying degrees of atypia, in association with a moderately cellular smooth-muscle stroma.

非典型性息肉状腺肌瘤是一种不常见的子宫的息肉状损害,表现为腺上皮和鳞状上皮细胞的增生,同时伴有不同程度的异型性,并与适度的细胞的平滑肌基质相关。

The cancer cells are in different differentiation periods: the chromatin of the young cancer cell's nucleus is rich in color and its cytoplasm is basophilous. The young cancer cells don't form into typical glandular cavity; The mature cancer cell is columnar or cubical and its nucleus is located at the base of the cell in gland tube-like arrangement; The decrepit cancer cell stain thin while its nucleus stain dense. The severer's nucleus disintegrate into small fragments. The decrepit cancer cell's arrangement is disorganized, only keeping its glandular shape.

显微镜下癌细胞呈现不同的分化程度:幼稚型癌细胞胞核染色质丰富,胞质嗜碱性,不形成典型腺腔;成熟型癌细胞呈柱状或立方状,细胞核位于细胞基部,呈腺管样排列;衰老型癌细胞胞桨染色变淡,胞核浓染,严重者胞核碎裂成细小碎片,衰老型癌细胞排列紊乱,仅保留腺体样结构轮廓。

According to the shape of head, the glandular hairs were divided into capitate and pehate glandular hairs.

根据腺毛头部形状可把腺毛分为盾状腺毛和头状腺毛,二者均发生得很早,它们的原始细胞都来源于原表皮,一般在茎尖第1和第2片叶原基的原表皮细胞以及茎的1~2节间原表皮细胞中开始发生。

The glandular component consisted of 1 or more patterns: papillary (46% of cases), glandular (42%), cribriform (33%), and flat (25%).

那些腺性成分的结构包括:乳头状(46%病例)、腺样(42%病例)、筛状(33%病例)、平坦状(25%病例)。

The anatomical localizations indicate that Al receptor and Dl receptor coexist in strionigro-strioentopeduncular neurons, and A2a receptor and D2 receptor coexist in striopallidals neurons. The heteromeric complexes of Al/D1、A2a/D2 receptor provided the molecular basis for the functional interactions of Al/Di and A2a/D2 receptor.

腺苷A1受体和多巴胺D1受体以及腺苷A2a受体和多巴胺D2受体分别共存於基底神经节中纹状体向黑质和脚内核投射的神经元以及纹状体向苍白球投射的神经元内。A1/D1、A2a/D2受体形成受体异聚复合体构成了受体一受体之间相互作用的分子基础。

Results Basal cell adenocarcinoma of prostate was composed of poorly differentiated solid carcinoma nests with many cellular nuclear mitoses arranged like basal cell carcinoma. Necrosis was in the middle of the carcinoma nest. Local differentiation to squamous cell, transitional cell and gland and structure like adenoid cystic carcinoma were found.

结果:前列腺基底细胞腺癌为分化差的实体癌呈基底细胞癌样排列,核分裂象多,癌巢中央伴坏死,可见局灶性鳞状细胞、移行细胞或腺管分化,也可出现腺样囊性癌样结构。

CONCLUSION摘要: Our successfully constructed cDNA libraries are fulllength libraries with high efficiency and can be screened by probes and antibodies to find the associated genes of the renal papillary adenocarcinoma.

结论摘要:我们构建的人肾乳头状腺癌及癌旁组织cDNA文库为高效、全长cDNA文库,可以用做探针、抗体等免疫学筛选,进一步探寻和肾乳头状腺癌相关的基因。

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