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This is prostatic intraepithelial neoplasia, a precancerous cellular proliferation found in a single acinus or small group of acini.

前列腺上皮内瘤变,可在单个腺泡或小群腺泡中见到的非典型增生。

In the microstructure of the digestive gland from treatment groups exposed to 10 μg·L-1 BP for 10 days, basophil granules in the acinus increased, the borders between cells of the acinus were obscured, and the number of food particles decreased.

观察结果表明,10μg·L-1 BP处理10d时,栉孔扇贝的鳃上皮粘液细胞增多,在回血管中血细胞出现聚集现象;消化盲囊腺泡中嗜碱性颗粒增多,腺泡内细胞间界限模糊。

The results showed that the method of rubbing the kerf then injection of retrovirus suspension into pancreas could more effectively mark the pancreatic cells than the caudal vein injection and the intraperitoneal injection did in vivo. Furthermore, this study also found that some acinus cells could accept injury stimulus signals to regenerate through resuming mitosis after pancreatic injury.

结果发现在活体条件下,与尾静脉注射及腹腔注射法相比,胰腺伤口涂抹并胰腺内注射反转录病毒的方法能够更有效的标记胰腺细胞;而且,通过对标记细胞的世系追踪研究证明,在胰腺损伤后,胰腺腺泡细胞能够接受损伤信号刺激发生再生。

Between P14 and P21,CIAPIN1 immunoreaction in the brain,heart and liverbecame much lower. However,between P21 and P28,CIAPIN1 immunoreactionin the heart,brain,liver and skeletal muscle became much lower,while with thekidney development,CIAPIN1 immunoreaction in the kidney became higher. Invarious tissues from adult mouse,CIAPIN1 immunoreaction could be seen incardiac muscle cell,brain,hepatocyte,epithelium of renal tubule,skeletal muscle,lung tissue,gastric mucosa and gland,acinus lienalis.2. Distribution of CIAPIN1 in normal fetal and adult human tissuesTo reveal the possible physiological role of CIAPIN1,we examined theexpression and distribution of CIAPIN1 in fetal and adult human tissues usingimmunohistochemistry. We found that CIAPIN1 was ubiquitously distributed infetal and adult tissues,and was localized in both the cytoplasm and the nucleus.

然而,在3个月大的成年鼠中,CIAPIN1阳性反应物在心、脑、肝和肾小管中的表达强度要低于P28小鼠;但CIAPIN1阳性反应物在成年鼠骨骼肌中较P28小鼠高。2、CIAPIN1蛋白在人5个月胚胎及成人多器官组织内的表达在人5月胚胎多器官组织中,CIAPIN1阳性反应物见于心脏、胆囊单层柱状上皮和粘膜、结肠粘膜、小肠粘膜和绒毛、肝脏、直肠腺体、胃粘膜、肾上腺束状带、甲状腺滤泡、脾索、胸腺小叶间隔、皮肤真皮层和汗腺、睾丸白膜和间质、脑组织内神经元和神经胶质、肺小支气管和肺泡、骨骼肌、肾脏皮髓质和肾小管、子宫内膜、胰腺腺泡和胰岛、卵巢、输卵管粘膜等绝大多数组织细胞。

With in situ DNA hybridization, the EBV genomes have been demonstrated in the labial glands of the Sjogren′s syndrome patients (16/28), moreover the elevated content of EBV DNA has been identified in those with more severe destruction of labial glands. It is concluded that EBV, vhich has a normal site of latency at salivary glands in a nonpathogenic state, may be reactivated in Sjogren′s syndrome patients and play a role in the pathogenesis of this disease.

另外,我们用原位杂交方法观察了EB病毒DNA在干燥综合征病人唇腺组织的存在状况,结果发现28例干燥综合征病人中16例为阳性,其中腺泡组织破坏严重者,EB病毒DNA的含量亦高,并且EB病毒主要分布于大量浸润的淋巴细胞中,其次位于腺泡上皮细胞内,少量见于腺泡腔中,以上结果提示,在干燥综合征病人EB病毒处于活跃的复制状态,干燥综合征病人靶器官受损与EB病毒的活跃复制及其诱导的免疫反应密切相关。

The first type of tumor(for example acinic cell carcinoma, oxyphilic cell adenocarcinoma, adenoid cystic carcinoma and so on) possesses the above spectra feature.

根据这一区域的差异可以将恶性肿瘤分为两大类:一类恶性肿瘤具有上述的光谱特征(如腺泡细胞癌、嗜酸细胞腺癌和腺样囊性癌等),另一类恶性肿瘤因为类型的不同在1500~1000 cm-1区域内峰形及峰位发生了很大的变化,不同于上述的光谱特征。

The hepatocytes which were injected into thymus could survive more than 2 weeks after injection and appeared to be irregular hepatic cells cords and sinusoid in shape, and severe vacuolar degeneration in 3 weeks.

本实验在未用任何免疫抑制剂的情况下,肝细胞胸腺内注入后1周、2周,显微镜下见植入胸腺内的肝细胞已生长出不规则的肝索及肝窦样结构。3周时的胸腺内植入的肝细胞仍存活,但空泡变性明显。

Results: In addition to 39 macrotumors (1 to 5/patient), chromogranin-positive endocrine microadenomas were found in 13 (72%) patients located within acini or close to ducts or islets.

结果:除39个大块肿瘤(1至5个/患者)之外,嗜铬素阳性的内分泌微腺瘤发现于13例患者(72%)的腺泡内或导管、胰岛的附近。

Objective To investigate the changes of structure of intra-acinar pulmonary artery,to see if inˉhaled NO could prohibit the forming and the developing of PH.

目的 通过研究大鼠肺腺泡内动脉结构变化,探讨外源性NO是否对肺高压的形成和发展具有阻抑作用。

The organization fixing of apoenzyme subtypes by IHC: The most increasing expressing were cPLA_2 and sPLA_2 in pancreas, they were found all over in the pancreatic acinar cells in 6h after PT, and spread out from the cells in 24h,then decreased after 72h.

用IHC技术对酶蛋白亚型组织定位方面:胰腺内的表达以sPLA_2和cPLA_2增加为主,6h时即遍布于胰腺腺泡细胞;24h时由于胰腺细胞的大量破坏,腺泡细胞外均可见sPLA_2和cPLA_2的高表达;72h后细胞内外sPLA_2和cPLA_2逐渐下降。

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