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Methods: Rat models of chronic renal failure were made by cut 5/6 kindney or fed with feedingstuff which contains adenine(0.75%) for 4 weeks. Experimental treatment was applied by giving Yi Shen Granule and the curative effect of Yi Shen Granule on ongoing pathological changes of CRF was studied. According to the data of CRF rats in weight, water wastage, hemanalysis(RBC、HGB、HCT、MCV、MCH), urinalysis(volume, specific gravity, pH, proteinuria), blood serum analysis(BUN、Cre、ALB、TP), kidney weight coefficient and kidney morphology ( the grade of expansile renal tubule and the diameter of glomerulus ),the pharmacological effect of Yi Shen Granule could be ascertained.

实验选用0.75%腺嘌呤饲喂法致大鼠慢性肾衰模型和5/6肾切除法致大鼠肾衰模型,考察益肾颗粒对慢性肾功能衰竭进行性病变的影响,以造模动物一般状况观察、血液学指标包括红细胞计数、血红蛋白、红细胞压积、平均红细胞体积、平均红细胞血红蛋白(RBC、HGB、HCT、MCV、MCH),尿液指标(尿量、比重SG、pH值、尿蛋白)、血清生化学指标包括尿素氮、肌酐、白蛋白、总蛋白(BUN、Cre、ALB、TP)、脏器解剖和病理观察指标(肾小管扩张分级评分和肾小球径长)做为判定依据。

Imaging studies showed that the positive rate of the ultrasound was 73.33%,the CT was 60.00%,the MRI was 75.00%,and the 99mTc-MIBI was 100.00%.All the patients were underwent parathyroidectomy of front neck incision, and were identified with parathyroid adenoma in 16 cases, hyperplasia in 1case and carcinoma in 2 cases. Follow-up was done from 10 months to 6 years after surgery.

影像学检查的阳性率:B超为73.33%,CT为60.00%,MRI为75.00%,99mTc-MIBI为100.00%。19例患者均经颈前弧形切口行甲状旁腺切除术,16例为甲状旁腺腺瘤;2例为甲状旁腺腺瘤伴灶性癌变;1例为甲状旁腺增生。

The principal microscopic lesions were the inflammation,and necrosis of the mucoase membranes of proventriculus,degeneration of the parenchymatous cells o...

主要的组织学变化为腺胃粘膜上皮坏死脱落、固有层水肿、有炎性细胞浸润、肌层有淋巴细胞浸润、肌细胞坏死、腺小叶腺细胞坏死、核浓缩。

The dynamic changes of the number of T or B lymphocytes and the content of immunoglobulin G, IgM, IgA in peripheral blood, the number of CD〓, CD〓 lymphocyte subpopulation, T〓 cells and IgG, IgM, IgA antibody-producing cells, the ratios of CD〓 and CD〓 T cells in immune organs (thymus, bursa of Fabricius and spleen) and immune tissues (cecal tonsils and Harderian glands), the content of IgA, IgM, IgG in local fluid (tear, tracheal fluid, intestinal fluid and bile) of one-day chicks infected with chicken infectious anemia virus and CIAV-infected chicks immunized with Newcastle disease vaccine were determined respectively by immunohistochemistry, immunogold-silves and immunoenzyme staining in order to reveal mechanism of immunopathogenesis of chicks infected with CIAV and influence of immune responses of CIAV-infected chicks to ND vaccine.

中文题名雏鸡感染鸡传染性贫血病毒后免疫变化和对新城疫疫苗的应答及其免疫机理副题名外文题名 Immune changes of chicks infected with chicken infectious anemia virus and immune response and mechanism to Newcastle disease vaccine immunity 论文作者郑世民导师刘忠贵教授学科专业基础兽医学研究领域\研究方向学位级别博士学位授予单位东北农业大学学位授予日期2002 论文页码总数105页关键词鸡传染性贫血病雏鸡新城疫疫苗馆藏号BSLW /2003 /S858 /9 本项研究采用免疫组织化学、免疫胶体金及免疫酶方法,首次对CIAV感染1日龄雏鸡和CIAV感染雏鸡ND疫苗免疫及vNDV攻击后,其外周血液的T细胞、B细胞数量和IgG、IgM、IgA含量;中枢免疫器官胸腺和法氏囊,外周免疫器官脾脏及呼吸道和消化道局部粘膜免疫组织哈德尔腺和盲肠扁桃体的ANAE〓、CD4〓、CD〓T细胞、IgG、IgM、IgA抗体生成细胞数量和CD〓与CD〓T细胞比值以及泪液、气管液、肠液、胆汁的IgA、IgM、IgG含量的动态变化规律和CIAV感染对ND疫苗的免疫保护率等进行了全面系统地研究。

Objective To report a case of pancreatic hepatoid adenocarcinoma, and to appraise the histological and clinical features and prognosis of AFP-positive pancreatic hepatoid adenocarcinoma.

目的 报道1例胰腺肝样腺癌,探讨血清甲胎蛋白AFP阳性的胰腺肝样腺癌的组织学表现、临床特点及其与预后的关系。

NGI and SI may be of help in more precise grading of villous adenoma of different atypical hyperplasic;The method being used in the cells'morphology analysis on the slide of tissues should be improved.

绒毛的核腺比指数及分层指数对大肠绒毛状腺瘤的非典型增生程度准确分级有一定价值;对组织切片进行细胞的体视学分析有待于技术改进。

A typical parotid malignancy is a painless, unilateral enlargement of the gland The purpose of radiologic examination is to define the size and anatomy of the mass, differentiate the intraglandular origin from extraglandular origin, determine its benign and malignant characteristics, and provide important preoperative information such as the location of the facial nerve.

典型的腮腺恶性肿瘤是无痛性,单侧腺体增大。放射学检查2的目的是确定肿块的大小和解剖关系,区分腺内来源还是腺外来源,确定其良恶性的特点,提供了重要的术前信息像面神经的关系。

During the surgery, the lesion was found to be a solid tumor. A surgical wedge biopsy was done and purulent dark yellow fluid was drained from the center of the mass. Histologically, there was a solid pattern of rhabdoid and anaplastic round or oval cells haphazardly arranged with poor differentiation. Immunohistochemical staining was positive for vimentin, a mesenchymal marker; the reticulin staining was consistent with carcinoma.

我们实施了手术切片及肿瘤中心脓状物引流,病理组织学上,我们发现了不规则或未分化的横纹状、圆形及椭圆形细胞;免疫组织染色上,细胞广泛的对非上皮标记vimentin呈阳性反应、且其reticulin染色呈现出腺癌的形式;肉瘤及腺癌的特色皆可在切片中看到,所以我们的诊断是类肉瘤性线癌。

All the patients had accepted TP chemotherapy and preponderated over 2 cycles,taxol 135 mg/m2,d1,cisplatin 20 mg/m2,d1-4.The chemotherapy was repeated every 21 days on two cycles.Results Among these 34 patients the complete responsewas 0,partial responsewas 3(8.82%),stable diseasewas 6(17.65%),progressive diseasewas 25(73.53%).The main toxicity,reactions were nausea,vomiting and hematologic toxicity.Conclusions TP regimen on advanced NSCLC after failure of NP show slow effectiveness. non-small cell lung cancer ; chemotherapy ; NP regimen ; TP regimen

本文回顾性分析我科自2002年6月—2004年12月间将应用NP方案进展的晚期NSCLC患者改用TP方案治疗的34例临床资料,观察并比较该方案的疗效、毒副反应。1资料与方法1.1临床资料34例经病理组织学及细胞学证实为NSCLC,男性21例,女性13例,年龄35~78岁,平均年龄54岁;鳞癌20例,腺癌12例,腺鳞癌2例,Ⅲb期24例,Ⅳ期10

The histological observation showed that the larvae of S .japonicum in superinfected snails were sluggish in development, irregular, shrunken, deformed, relatively small in number as compared with the control. The sporocysts contained few germ balls or immature cercariae and most of the digestive glands of superinfected snails were atrophiej.

组织学观察发现各双重感染组钉螺消化腺萎缩,消化腺盲囊间隙只有少量血吸虫子胞蚴,血吸虫子胞蚴皱缩、变形及不规则,且子胞蚴中只含稀疏的尾蚴胚球,有的子胞蚴中已无胚球;而单独感染血吸虫的对照组中血吸虫均发育到成熟的子胞蚴或尾蚴。

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