腺学

Abstract］ objective to study the pathological features and histopathological type and differential diagnosis of hepatic focal nodular hyperplasia.methods the clinicopathological characteristics of 40 cases of fnh were studied.all were evaluted by use of paraffin embedded sections and he staining before light microcope observation.results there were 28 females and 12 males fnh patients whose age were from 16 to 62 years（median 41.3）,all alpha-fetoprotein was negative and had no hepatitis history.25 cases were classic type showed characteristic central stellate fibrotic scar,composed of fibrous connestive tissue and tortuous blood vessels.8 cases were telangiectic type,the left were mixed type and adenomatoid type.conclusion fnh is a reactive proliferation of hepatic cells to local blood vessel anomalies,it is not realy a tumor.its differential diagnosis includes hepatic adenomatous hyperplasia nodule,hepatic anaplasia nodular hyperplasia,fibrolamellar hepatocellular carcinoma and hepatocellular adenoma.

目的 探讨肝局灶性结节性增生的病理形态特点、组织分型及鉴别诊断。方法分析40例肝局灶性结节性增生的临床资料，并采用石蜡包埋he染色光镜下观察其组织学特点。结果 40例肝局灶性结节性增生患者中，女28例，男12例，年龄18~62岁，平均年龄41.3岁，所有病例术前均无肝炎病史，甲胎蛋白阴性，组织学上25例为经典型，有特征性的中央纤维瘢痕，由纤维结缔组织及扭曲血管组成。8例为毛细血管扩张型，其余为混合型及腺瘤样增生型。结论肝结节性增生是一种肝细胞对局部血管的异常反应性增生，并非真性肿瘤，主要与肝腺瘤样增生性结节、肝间变性结节状增生、肝纤维板层癌及肝细胞腺瘤鉴别。

Quantitative chromatics analysis of large bowel tumorous adenoma and adenocarci-noma was made by the methods of computer image processing.

本文通过对大肠腺瘤和腺癌组织进行计算机图像定量分析，表明大肠腺瘤和腺癌的腺上皮细胞以正常杯状细胞和柱状细胞的色度学特征分布为基准可划分为两大类：杯状细胞性腺上皮和柱状细胞性腺上皮。

The results indicate its pituitary belongs to back-abdomen gland; neurohypophysis in the middle; pre-adenohypophysis the front and edge of the back of pituitary with PRL cells and ACTH cells; mesoadenohypophysis middle and behind of back with GH cells, GTH cells and TSH cells; meta-adenohypophysis behind of abdomen with only one kind of secret cells by histology.

结果表明：瓦氏黄颡鱼脑垂体为背腹型腺体。神经垂体居中，前腺垂体位于垂体背面前部和后缘，由PRL细胞和ACTH细胞组成；中腺垂体位于垂体中部及背面后部，包括GH细胞、GTH细胞和TSH细胞，后腺垂体位于垂体腹面后方，组织学研究仅见一种分泌细胞。

Result: In the 3 categories and 10 exemples of congenital malformation fetus, The morphologic observation and histological observation of thymus in syndactylia, ectrodactylia and Siamese fetus was no obvious abnormity, but the morphologic observation and his-tological observation of thymus in anencephaly fetus appeared Obvious abnormity.

结果：三类、10例先天畸形胎儿中，并、缺指畸形和联体畸形胎儿胸腺的大体形态和组织学观察无明显异常，无脑畸形胎儿胸腺的大体形态和组织学观察出现明显异常。

Objective To study the diagnostic and therapeutiic features of prolacfinoma in methods 23 male Patients with prolactinoma patienta in clinical manifestation, pathologic, endocrinological, radiographic andtherapeutic features.

目的 分析总结男性垂体泌乳素腺瘤的诊断和治疗特点：方法对10年间23例男性垂体泌乳素腺瘤患者的临床表现和肿瘤的病理学、内分泌学、影像学及治疗特点进行分析。

These two kind of diseases have their own characteristics in clinical and imaginal representation.but misdiagnosis is still happened.

乳腺纤维腺瘤与乳腺叶状囊肉瘤在临床和影像学表现方面都有其特征性，但临床上仍常出现误诊的情况，我们于2002年4月收治1例发病于妊娠哺乳期的28岁右乳巨大肿块女性病人，术前根据临床表现及影像学检查的结果考虑右乳叶状囊肉瘤的诊断，而术后的病理报告为乳腺纤维腺瘤。

In the article, we took part sample out of 158 patients to exam the expression level of Bcl-2 and Fas in myasthenic thymus tissue, and to find the role of which in whole pathogenesis. we also try to find the role of neopterin and sIL-2R through examing the concentration of neopterin and sIL-2R in peripheral blood of 26 MG patients. Material and methods1.select of case: to choose 158 patients who wear followed up from 1988 to 2002 after operation. All patients were diagnosed as MG, and treated with same medical cure during period of preoperation and post operation. 2.Collectionofdata:.To collect all data through designing a uniform follow-up table for thymectomized patients ,and to analysis the effect of factors including age, gender, disease duration of preoperation, clinic types and pathological types to prognosis at three follow-up period?

本文拟在对全组病例的远期预后进行流行病学统计分析的基础上，通过抽取一定量样本，研究重症肌无力患者胸腺组织中伽 12、Fas的异常表达及生发中心的形成在重症肌无力发病机制中可能的作用，以及它们对胸腺切除术后远期预后的影响；与之相似，通过检测部分样本外周血清中新碟吟和可溶性IL－2受体的浓度及其与正常对照组的差异，以期推测两者在重症肌无力起病及病情进展中的作用和意义，并分析其对胸腺切除术后远期预后的影响。

Three infectious bronchitis virus isolates named as Q1, J2 and T3 were isolated from proventricular tissue taken from vaccinated chicken flocks in China The biological characteristics of the three isolates were observed.

中文题名传染性支气管炎致腺胃病变毒株变异的分子基础及我国和东南亚分离株的分子流行病学研究副题名外文题名 Molecular basis for variation of proventriculus pathogenic IBV isolates and molecular epidemiology of IBV isolates from China and southeast Asia 论文作者蒋贻海导师陈溥言教授学科专业预防兽医学研究领域\研究方向动物分子病毒学及免疫学学位级别博士学位授予单位南京农业大学学位授予日期2002 论文页码总数127页关键词鸡传染性支气管炎传染性支气管炎病毒腺胃毒株馆藏号BSLW /2003 /S855 /9 从我国接种过传染性支气管炎疫苗的幼鸡群的腺胃组织中分离得到三个传染性支气管炎毒株Q1、J2和T3，并对它们的部分生物学特性进行研究。

These 375 patients had a median age of 50.57±10.46(range,19-72) with 87.4%HBsAg positive and 4.3%anti-HCV antibody positive;The apparent peak incidence age was 40～60 years old,and the ratio of male to female was 10.7:1;The 3 and 5 year postoperational survival rate were 52%and 38%;The tumour numbers(p=0.000),tumor size(p=0.025),histological pattern (p=0.000),nuclear features(p=0.000),differentiation(p=0.001) and vascular invasion(p=0.000) were significantly correlated with prognosis.The postoperational survival time of thin trabeculae pattern,compact pattern and pseudoglandular pattern were significantly longer than that of thick trabeculae, scirrhous pattern,and solid patternp＜0.009the postoperational survival time of 1 and 2 grade based on nuclear features were significantly longer than that of 3 and 4 grades(p=0.000The small cell variant,osteoclast-like giant cell variant, and spindle cell variant were mainly composed of thick trabeculae pattern and solid pattern,which were significantly different from that of clear cell variant.

结果1。本组资料显示肝细胞癌发病年龄19～72岁，平均50.57±10.46岁，发病高峰年龄40～60岁，男女比例为10.7：1；HBsAg87.4%，anti-HCV抗体4.3%；术后3年生存率为52%，5年生存率为38%；肿瘤数目(p=0.000)、肿瘤大小(p=0.025)、组织学结构类型(p=0.000)、核分级(p=0.000)、分化程度(p=0.001)及血管浸润均(p=0.000)与预后明显相关；其中组织学结构类型中细梁状型生存时间与致密梁状型和腺样型无明显区别(p＞0.05)而明显高于粗梁状型、实性型和硬化型(p≤0.009)，硬化型生存时间与实性型之间无明显区(p＞0.05)而明显低于其余各型p≤0.006核分级1级与2级生存时间无明显区别(p＞0.05，核分级3级与4级生存时间无明显区别(p＞0.05)，而核分级3级生存时间明显低于2p=0.000小细胞型、巨细胞型和梭形细胞型主要由实性型和粗梁状型组织学结构类型构成，明显不同于透明细胞型(主要由细梁状型和粗梁状型构成(p≤1.006)。2。

These two kind of diseases have their own characteristics in clinical and imaginal representation.but misdiagnosis is still happened.We misdiagnosis one huge breast mase of 28 years old female in April,2002,whose diease come on during pregnancy and lactation.

乳腺纤维腺瘤与乳腺叶状囊肉瘤在临床和影像学表现方面都有其特征性，但临床上仍常出现误诊的情况，我们于2002年4月收治1例发病于妊娠哺乳期的28岁右乳巨大肿块女性病人，术前根据临床表现及影像学检查的结果考虑右乳叶状囊肉瘤的诊断，而术后的病理报告为乳腺纤维腺瘤。

I didn't watch TV last night, because it .

昨晚我没有看电视，因为电视机坏了。

Since this year, in a lot of villages of Beijing, TV of elevator liquid crystal was removed.

今年以来，在北京的很多小区里，电梯液晶电视被撤了下来。