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腺嘌呤

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Especially in the respects of antivirus and restraint of cancer cells, adenine derivatives have obvious effect and alluring prospect of clinical application.

特别是在抗病毒和抑制癌症细胞方面,腺嘌呤类衍生物作用明显,具有诱人的临床应用前景。

Young male and female rats were administrated each adjusted adenine (6, 50 and 100 mg/mL) for 8 weeks (3 times/week).

年轻雄性和雌性大鼠分别给与一种预定浓度的腺嘌呤(6、60及100mg/mL)共8周(3次/周)。

Of the four nucleotides that comprise DNA molecules, adenine, turns out to have a particularly high affinity for gold.

在组成DNA分子的四种核苷分子中,属腺嘌呤与金的亲合力最强。

Dose effect of adenine and cytosine irradiated by 20 keV N+ and Ar+ was studied.

研究了经20keV的氮离子、氩离子辐照后,腺嘌呤与胞嘧啶的残存率与注入剂量的关系。

It occurs in combined form in many important Biological molecules, particularly DNA (where its complementary Base is adenine).

经常以组合形式出现于许多重要的生物分子中,尤其是去氧核糖核酸(其中的补充基底为腺嘌呤)。

Objective To identity adenine phosphoribosyltransferases in Schistoma japonicum and analyze their structural features.

目的 鉴定日本血吸虫中存在的腺嘌呤磷酸核糖转移酶,分析其蛋白结构特征。

Methods We used retrograde CTb immunocytochemical and NADPH-d histochemical staining methods after microinjecting CTb into cortical amygdaloid.

采用霍乱毒素B亚单位逆行追踪和还原型尼克酰胺腺嘌呤二核苷酸脱氢酶组织化学双重染色相结合的方法。

The results show that all the hmgr genes from pigs, cattle and chickens are astable enzyme proteins with the same gene sequence characteristics and encoding protein and physical and chemical properties; all the amino acid sequences have a high degree of homology, containing two conservative HMG-CoA binding motifs and two NADPH binding motifs; all the amino acid sequences, containing signal peptide, are secreted proteins; they are all hydrophobic transmembrane proteins with five transmembrane domains; random coil and α-helix are the main structural elements in the HMGR polypeptide chain; all the predictions of three-dimensional structure are V- shaped; there are more closer evolution relationship between the HMGR gene from pigs and cattle.

结果表明:猪、牛和鸡HMGR基因序列特点及编码蛋白质理化性质基本相同,均属不稳定类酶蛋白;保守结构域氨基酸序列具有高度的同源性,均含有保守的2个β-羟基-β-甲基戊二酸单酰辅酶A结合基序和2个还原性烟酰胺腺嘌呤二核苷酸结合基序;均有信号肽,属分泌型蛋白质;属于跨膜的疏水性蛋白,均有5个跨膜结构域;无规则卷曲和α-螺旋是HMGR多肽链中的主要结构元件;三维结构预测都呈"V"字形;猪和牛HMGR基因的进化关系最近。

In the first step the 2' hydroxyl group of the adenine of the branch point sequence attacks the phosohdiester bond 5' to the G of the GT (5' splice site).

在第一步骤2 '羟基组对腺嘌呤的分支点序列攻击phosohdiester债券5 '向克的gt ( 5 '剪接位点)。

At last, adsorbent and covalent Ag nanoparticles modified electrodes were prepared by adsorbent and covalent method, respectively. The electrochemical behaviours of SCN-, brilliant cresyl blue and nicotinamide adenine dinucleotide on modified electrode were studied by Cyclic voltammetry, differential pulse voltammograms and electrochemical impedance spectroscopy.

最后,用吸附法和共价键合法制备了吸附型和共价自组装银纳米修饰电极,采用循环伏安法、示差脉冲伏安法和交流阻抗谱等电化学方法研究了SCN-、灿烂甲酚蓝和还原型烟酰胺腺嘌呤二核苷酸的电化学行为。

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