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腺嘌呤

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Adenosine, a metabolite of adenine nucleotides, is one of the major neuromodulators.

腺苷是腺嘌呤核苷酸的代谢产物,是一种重要的神经调质。

The isolated working heart model was set up, high-performance liquid chromatography were used to measure myocardial adenosine triphosphate,total adenine nucleotides, while left ventricular end-diastolic pressure,left ventricular developed pressure, and rate of change of left ventricular pressure were determined before and after preservation.

对照组用St Thomas停搏液停搏并保存大鼠心脏6小时;实验组在St Thomas液中加入前列腺素E1(5 μg/L)停搏并冷保存6小时,利用离体鼠心非循环式Langendorff灌流功能测定模型,测定左心室舒张期末压、左心室发展压和左心室压力变化率,并检测心肌细胞线粒体三磷酸腺苷、腺嘌呤核苷酸总量。

The reactive conditions for ATP production from adenine by Mucor were investigated, especially the effects of additives.

采用毛霉菌由腺嘌呤转化合成腺三磷,在综合研究其转化条件的基础上,进一步研究添加剂对提高ATP产率的影响。

ADP A nucleotide consisting of adenine and ribose with two phosphate groups attached.

腺苷二磷酸:一种由腺嘌呤和核糖再加上两个磷酸组成的核苷酸。

After thecomplete genome extraction of the strain was performed, the genomic DNA was partiallydigested by restriction enzyme Sau3AⅠ, the DNA fragments from 1 to 5Kb was clonedinto prokaryote expression vector pET-28a-c, and transformed host bacteria. The resultsshowed that we succeeded in constructing the gene expression library of haemophilusparasuis serovar 5, which is fundamental for the study of advanced gene screening. Inaddition, primer design was performed based on haemophilus influenzae in this study. In addition, PCR was performed by using genomic DNA of haemophilus parasuisserovar 5 as the template. The results demonstrated that we obtained two neo-gene:23SrRNA gene(conserved gene belonging to the large-subunit of ribosome) and adenylatecyclase gene(encodes adenylate cyclase and participates in converting adenyl nucleosidetriphosphate to cyclic adenosine3",5"-monophosphate). Furthermore, the phylogeneticanalyses between the species was performed, and neighbor-joining tree was constructedbased on comparison of 23S rRNA gene sequences, so it was illuminated betweenHaemophilus parasuis and other species in molecular evolution relationship.

选择我国流行优势菌株副猪嗜血杆菌血清5型地方株为研究对象,提取细菌基因组DNA,用限制性内切酶Sau3AⅠ对基因组DNA进行部分酶切,回收大小为1~5Kb的DNA片段,将其连接入原核表达载体pET-28a-c,最后转化宿主菌,结果成功地构建了基因表达文库,为后续的基因筛选工作奠定基础;另外,本研究选择嗜血杆菌属的流感嗜血杆菌为参考对象进行引物的设计,以副猪嗜血杆菌血清5型地方菌株的基因组DNA为模板,进行PCR扩增反应,结果表明成功地获得两个新基因:23S rRNA基因(存在于核糖体大亚基中的保守性基因)和腺苷酸环化酶基因(负责将腺嘌呤核苷三磷酸转变为环腺苷酸),并进一步做了不同物种之间的分子系统发育分析,构建了基于23S rRNA基因的邻接法系统发育树,阐明了副猪嗜血杆菌与其它菌种的分子进化关系。

The Taohezhenwu Decoction has good curative effect in treating and preventing CRF of rats induced with adenine by improving the renal function, electrolyte disturbances, acid-base equilibrium, hemophthisis and the function of SOD, reducing the harm of NO, TNF-α, and lessening or delaying the deterioration of nephron.

桃核真武汤能改善腺嘌呤大鼠慢性肾衰模型的肾功能、调节电解质酸碱平衡紊乱、纠正贫血、减少尿蛋白的丢失、减少NO与TNF-α损伤、提高SOD的保护作用、一定程度上防止肾单位的恶化,对SD大鼠腺膘呤所致之CRF的防治有肯定的疗效。

The electrocatalytic reoxidation properties of guanine, adenine, and theirmixture by the Iron hexacyanoferrate films were determined and show differentelectrocatalytic properties in K+ and Na+ aqueous solutions.

铁赤血盐薄膜在K+和Na+的电解液中对於鸟嘌呤、腺嘌呤和该混合状态下显示有不同的电催化氧化性质。

They were two new compounds, [cyclo(Pro-Val-Phe-Phe-Pro-Val-Phe-Ser-Leu),7],[2-N-(1-methoxycarbonylethyl)guanosine, 10], and eight known compounds,(p-hydroxybenzoic acid, 1),(methyl succinate, 2),(russulaceramide, 3),(phenylalanine, 4),(guanine, 5),(β-carboline, 6),(uridine, 8), and (adenosine, 9). All the compounds were isolated from Amanita exitialis for the first time.

分别为:对羟基苯甲酸(p-hydroxybenzoic acid,1)、丁二酸二甲酯(methyl succinate,2)、神经酰胺(russulaceramide,3)、苯丙氨酸(phenylalanine,4)、鸟嘌呤核苷(guanine,5)、β-咔啉(β-carboline,6)、环(脯氨酸-缬氨酸-苯丙氨酸-苯丙氨酸-脯氨酸-缬氨酸-苯丙氨酸-丝氨酸-亮氨酸) [cyclo(Pro-Val-Phe-Phe-Pro-Val-Phe-Ser-Leu),7]、尿嘧啶核苷(uridine,8)、腺嘌呤核苷(adenosine,9)、2-N-(1-甲氧羰基乙基)鸟苷[2-N-(1-Methoxycarbonylethyl)guanosine, 10]。10个化合物均为首次从致命鹅膏中分离得到,其中化合物7和10为新化合物。

Guanosine overproducing mutant was derived from Bacillus subtilis T1001 by using ultraviolet and diethyl sulfate. The mutant was selected directionally and step wisely on the agar plates containing methionine sulfoxide and 8 azaguanine(8 AG).

以枯草芽孢杆菌T1 0 0 1为出发菌株,经紫外线、硫酸二乙酯逐级诱变处理,选育出腺嘌呤缺陷型菌株,然后经蛋氨酸亚砜、8 氮鸟嘌呤( 8 AG)结构类似物平板定向筛选,获得鸟苷高产菌株TA2 0 8。

In DNA the corresponding sugar is the closely related deoxyribose. A ribose molecule combined with adenine, guanine, cytosine, or uracil forms a nucleoside; adding a phosphate group forms a nucleotide.

去氧核糖核酸中相应的糖类和去氧核糖密切相关核糖分子和腺嘌呤、鸟嘌呤、胞嘧啶或尿嘧啶形成核;再加上磷酸盐和磷酸酯便成为核。

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