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Our results demonstrate: The structures of the organs are normal, and the shapes of cells are clearly visible. There are lots of positive brown granules in Chief cells and Parietal cells in abomasum as well as the mucosa epithelial cells and gland cells of duodenum. Three bands with a molecular mass close to 120KDa、110KD and 98KDa were identified by Western Blot. The Ob-R levels of 120KDa in abomasum were significantly higher than that of in small intestine. The levels of 110KDa were similar in the two organs. The expression of 98KDa Ob-R was weak.

HE染色结果显示,各组织结构正常,细胞形态清晰可见;免疫组织化学SABC染色显示,在皱胃胃体部固有层胃底腺的主细胞和壁细胞及十二指肠黏膜上皮细胞和固有层肠腺的柱状细胞中均可见大小数量不等的棕黄色颗粒;western Blot 实验发现,在胃和小肠均检测到120KDa、110KDa和98KDa三条带。120KDa长型瘦素受体蛋白在胃中表达量显著高于小肠中的表达;110KDa的短型瘦素受体蛋白,在小肠和皱胃中表达量接近。98KDa短型受体蛋白在胃和小肠表达均较弱。

At first, I was sent to working with the Protocol Nurse---Mary Caroll, to watch how she handling these Phase I patients; how to coordinate with Lab, PI and nursing staffs.

更重要的是,本人协助苏五洲主任已筹划一个PI-initiated临床试验:以「上皮生长因子基因突变个制化之肺腺癌第二线治疗疗效」之研究。

Methods] A total RNA from 10 cases withovarian papillary serous cystadenocarcinoma and normal ovarian tissues were extracted by a single step method of gene chip. The cDNA retro?鄄transcribed from equal quantity mRNA derived from 10 cases with ovarian papillary serous cystadenocarcinoma and normal ovarian tissues. The cDNA strand was labeled with fluorescent Cy5 and Cy3(normal ovarian epithelial cells) as probes.

方法] 采用基因芯片技术,按一步法分别抽提10例卵巢浆液性乳头状囊腺癌患者的癌组织和正常卵巢组织的总RNA并纯化mRNA;逆转录合成以Cy5荧光标记卵巢癌细胞和Cy3荧光标记正常卵巢上皮细胞的cDNA作为探针,在含有8 464点人类体细胞基因模板的表达谱cDNA芯片上进行杂交。

Heregulin-αwas a cytokine which was synthesized and secreted by mammary mesenchyme,adjacent to lobuloaveolar structures.

Heregulin-α是主要由乳腺间质细胞合成和分泌的细胞因子,作用于乳腺导管和腺泡上皮细胞。

A core needle biopsy misdiagnosed PASH in 13 cases out of 28 cases and vacuum-assisted biopsy correctly identified PASH in all 3 cases.

4细胞性纤维腺瘤和囊肉瘤:PASH缺乏真正的间叶细胞过生长的现象,其细胞缺乏多形性,无核分裂象,也没有纤维腺瘤或囊肉瘤的上皮成分的生长类型。

Here is an adenocarcinoma in which the glands are much larger and filled with necrotic debris.

此腺癌的腺体较大,腺腔内充满了坏死的上皮细胞碎片。

We found, GLP-1-IR cells in various guts of rat, pig and foetus of human with distribution scatteredly among the basal portion of intestinal glands. The cell shape corresponded with open type cells, i.e. L-cells. The density of GLP-1-IR cells was different in races, but the distribution regularity of GLP-1-IR cells was same. It showed that a continuous increase from the proximal to the distal portion of small and bowel.

结果发现:在各段肠管都可见到GLP-1-IR细胞;GLP-1-IR细胞散在于肠腺的柱状上皮细胞之间,多位于肠腺的基底部,呈开放型内分泌细胞形态,即L细胞;不同种属问GLP-1-IR细胞密度不同,但分布规律相同,即自小肠和大肠的近端向远端逐渐增大。

Cytokines are strongly expressed in acini epithelial cells than in the other areas,these cells may play a critical role in the development of autoimmune sialoadenitis.The expression of cytokines is not correlated with the pathological gradation.

唇腺腺泡上皮细胞中细胞因子的表达较其他部位明显增强,提示这此细胞在自身免疫性唾液腺炎的发生中起关键作用,而且细胞因子的表达与病理分级有相关性。

In rat esophagus, the positive varicosities and fibres could be observed in the circular muscle layer and the muscularis mucosae layer at 21st day before birth. With the development of rat digestive tract, neurokinin A-immunoreactivity positive nerves could be observed gradually in the epithelium, submucosa, longitudinal muscle layer, myenteric plexus and submucosal plexes, while mature nerve fibres could be seen at one month after birth. 2. In rat stomach, the positive reaction of NKA initially happened in the myenteric plexus at the 14th day of embryo, and then appeared on circular muscles, longitudinal muscles, submucosal, muscularis mucosae, lamina propria and epithelium. 30 days after birth, expression of NKA is same as seen in adaulthood. 3. In rat small intestinal, the NKA-IR could first be found in the myenteric plexus of the duodenum, jejunum and ileum at 14th , 15th and 17th day before birth respectively. Then the NKA-IR occurred in the longitudinal muscle layer, circular muscle layer, intestinal villus, intestinal gland, muscularis mucosae, submucosa, submucosal plexes, mucosa plexus and deep muscular plexus.

结果 1、在食管,于胚胎21天的粘膜肌层和环肌层内观察到神经激肽A免疫阳性膨体纤维,出生后,随幼鼠的生长发育,相继在上皮,粘膜下层,纵肌层、肌间丛、粘膜下丛有NKA-IR表达,30天时已和成年鼠相似;2、在胃,首先于胚胎14天的肌间丛出现NKA-IR的表达,随发育相继在环肌、纵肌,粘膜下层、粘膜肌、固有膜及上皮内出现NKA-IR的表达,30天时具备成年鼠的分布特征;3、在小肠,分别于胚胎14、15、17天的十二指肠、空肠和回肠的肌间丛处出现NKA-IR的表达,随发育相继出现在纵肌、环肌、绒毛、小肠腺周、粘膜肌、粘膜下层、粘膜下丛、粘膜丛、深肌丛。

Thus, there may be some correlation between those substances and development of gonads of Styela plicata.

而在神经腺上,ER-α和ER-β免疫阳性物质定位在上皮细胞的胞核。

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It has been put forward that there exists single Ball point and double Ball points on the symmetrical connecting-rod curves of equilateral mechanisms.

从鲍尔点的形成原理出发,分析对称连杆曲线上鲍尔点的产生条件,提出等边机构的对称连杆曲线上有单鲍尔点和双鲍尔点。

The factory affiliated to the Group primarily manufactures multiple-purpose pincers, baking kits, knives, scissors, kitchenware, gardening tools and beauty care kits as well as other hardware tools, the annual production value of which reaches US$ 30 million dollars.

集团所属工厂主要生产多用钳、烤具、刀具、剪刀、厨具、花园工具、美容套等五金产品,年生产总值3000万美元,产品价廉物美、选料上乘、质量保证,深受国内外客户的青睐

The eˉtiology of hemospermia is complicate,but almost of hemospermia are benign.

血精的原因很,以良性病变为主。