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Between P14 and P21,CIAPIN1 immunoreaction in the brain,heart and liverbecame much lower. However,between P21 and P28,CIAPIN1 immunoreactionin the heart,brain,liver and skeletal muscle became much lower,while with thekidney development,CIAPIN1 immunoreaction in the kidney became higher. Invarious tissues from adult mouse,CIAPIN1 immunoreaction could be seen incardiac muscle cell,brain,hepatocyte,epithelium of renal tubule,skeletal muscle,lung tissue,gastric mucosa and gland,acinus lienalis.2. Distribution of CIAPIN1 in normal fetal and adult human tissuesTo reveal the possible physiological role of CIAPIN1,we examined theexpression and distribution of CIAPIN1 in fetal and adult human tissues usingimmunohistochemistry. We found that CIAPIN1 was ubiquitously distributed infetal and adult tissues,and was localized in both the cytoplasm and the nucleus.

然而,在3个月大的成年鼠中,CIAPIN1阳性反应物在心、脑、肝和肾小管中的表达强度要低于P28小鼠;但CIAPIN1阳性反应物在成年鼠骨骼肌中较P28小鼠高。2、CIAPIN1蛋白在人5个月胚胎及成人多器官组织内的表达在人5月胚胎多器官组织中,CIAPIN1阳性反应物见于心脏、胆囊单层柱状上皮和粘膜、结肠粘膜、小肠粘膜和绒毛、肝脏、直肠腺体、胃粘膜、肾上腺束状带、甲状腺滤泡、脾索、胸腺小叶间隔、皮肤真皮层和汗腺、睾丸白膜和间质、脑组织内神经元和神经胶质、肺小支气管和肺泡、骨骼肌、肾脏皮髓质和肾小管、子宫内膜、胰腺腺泡和胰岛、卵巢、输卵管粘膜等绝大多数组织细胞。

With in situ DNA hybridization, the EBV genomes have been demonstrated in the labial glands of the Sjogren′s syndrome patients (16/28), moreover the elevated content of EBV DNA has been identified in those with more severe destruction of labial glands. It is concluded that EBV, vhich has a normal site of latency at salivary glands in a nonpathogenic state, may be reactivated in Sjogren′s syndrome patients and play a role in the pathogenesis of this disease.

另外,我们用原位杂交方法观察了EB病毒DNA在干燥综合征病人唇腺组织的存在状况,结果发现28例干燥综合征病人中16例为阳性,其中腺泡组织破坏严重者,EB病毒DNA的含量亦高,并且EB病毒主要分布于大量浸润的淋巴细胞中,其次位于腺泡上皮细胞内,少量见于腺泡腔中,以上结果提示,在干燥综合征病人EB病毒处于活跃的复制状态,干燥综合征病人靶器官受损与EB病毒的活跃复制及其诱导的免疫反应密切相关。

Its pathology change is tiny stone often accompanies the kitchen sex that has prostate, chronic inflammation changes, stone is big person prostate canal and gland bubble dilate, there is size to differ all round, appearance the bursa antrum of each different, clinking skin cell covers its wall, between gland bubble soak of cell of form having garden and fiber are changed, stone can be located in gland to run mouth office, yi Ke is in gland body deep, the person that affect for a long time.

其病理变化是微小的结石常伴有前列腺的灶性,慢性炎症变,结石大者前列腺管和腺泡扩张,周围有大小不等,形状各异的囊腔,其内壁无上皮细胞覆盖,在腺泡间有园形细胞浸润及纤维化,结石可位于腺管开口处,亦可在腺体深部,长期感染者。

The expressions of E-cadherin and α-catenin in specimens of 54 breast carcinomas and 21 normal breast tissues around tumor were measured by immunohistochemical method. Results In normal breast tissues, E-cadherin and α-catenin were expressed on cell membrance of ductal and acinic cells. No abnormal expressions were found in normal breast tissues. The abnormal expression rates of E-cadherin and α-catenin in breast cancer were 51.9% and 63.0% respectively.

结果 21例癌旁正常组织中,上皮钙黏蛋白和α-连接素均主要定位于腺泡或导管上皮细胞膜上,显示了细胞-细胞间交界和细胞轮廓,二者均表达正常;54例乳腺癌组织中上皮钙黏蛋白和α-连接素的异常表达率分别为51.9%和63.0%。

Results With the expression in normal salivary gland as a standard, low C-erbB-2 mRNA expression was seen in adenolymphoma, basal cell adenoma. However, various degrees of over-expression of C-erbB-2 oncogene mRNA were detected in pleomorphic adenoma, mucoepidermoid carcinoma,acinic cell carcinoma ,adenoid cystic carcinoma ,papillary cystic carcinoma,and myoethelial cell carcinoma.

结果 正常涎腺和涎腺肿瘤中发现不同程度C-erbB-2mRNA的表达,以正常涎腺组织的表达水平为基准,在腺淋巴瘤、基底细胞腺瘤呈现低表达、无表达或与正常涎腺组织表达水平相似,多形性腺瘤、粘液表皮样癌、腺泡细胞癌、腺样囊性癌、乳头状囊腺癌和肌上皮癌则呈现不同程度的过表达。

Decrease in serum estradiol level after ovariectomy leads to reduce of lipid quality of the meibomian gland acinar epithelium, which is one of causes for the dysfunction of meibomian gland.

卵巢切除后血清雌二醇水平降低,可造成睑板腺腺泡上皮细胞脂质减少,是导致睑板腺机能障碍的原因之一。关键词:卵巢切除术;大鼠;睑板腺机能障碍;组织构建

The most common types are Meibomian gland adenoma, papilloma, melanoma (eyelid, conjunctiva, sclera, iris, ciliary body, choroid), squamous cell carcinoma, adenoma, adenocarcinoma, lymphoma, medulloepithelioma, ganglioglioma, osteosarcoma, mast cell tumor, and optic nerve sheath meningioma.

最常见的类型是睑板腺腺瘤,乳头状瘤,黑色素瘤(眼睑,结膜,虹膜,睫状体,脉络膜),鳞状细胞癌,腺瘤,腺癌,淋巴瘤(视网膜,脉络膜,睫状体),髓上皮瘤,神经节胶质瘤,骨肉瘤,肥大细胞瘤和视神经鞘脑膜瘤。

Barrett's esophagus, the most important risk factor in the deelopment of adenocarcinoma of the esophagus, is a metaplastic condition in which the normal squamous epithelium of the esophagus is replaced by columnar or glandular epithelium.

Barrett食管,是食管的正常的鳞状上皮被柱状或腺状上皮所取代的一种化生状态,为食管腺癌的发生中的最重要的危险因素。

Methods: The method of immunohistochemistry was used to study the expression of CD44v6 protein in the cases, including 10 normal cervix, 15 dysplasia, 16 squamocellular carcinoma in situ , 1 adenocarcinoma in situ , 27 invasive squamocellular carcinoma, and 15 invasive adenocarcinom...

用免疫组化法检测 10例正常宫颈上皮、15例宫颈上皮不典型增生、16例宫颈原位鳞癌、1例宫颈原位腺癌、2 7例宫颈浸润鳞癌、15例宫颈浸润腺癌中CD44v6蛋白的表达,实验结果以图像处理与分析系统进行半定量处理后进行统计分析。

Itplayed a role in the morphogenesis and ductal migration of mammary epithelial cells, promoted theresponsiveness of these cells to lactogenic hormones in vitro and induced the differentiation ofmammary epithelium into secretory lobuloalveoli.

Heregulin-α是细胞间信号蛋白,它可增强体外培养的乳腺上皮细胞对催乳素的敏感性,在乳腺上皮细胞形态发生、导管形成,以及诱导乳腺上皮细胞分化成分泌腺泡中扮演了重要角色,对乳腺发育和乳腺功能调控具有重要作用。

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随着死亡的吉他手Schuldiner接受主唱的职务,乐队在现实中树立了重要的影响。

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Closes the eye, the deep breathing, all no longer are the dreams as if......

关闭眼睛,深呼吸,一切不再是梦想,犹如。。。。。。