腔中央的

The 20S catalytic core of the 26S proteasome has the shape of a barrel made of four rings which are composed of seven differentαsubunitsα_1-α_7 at two outer rings and seven differentβsubunitsβ_1-β_7 at two inner rings at which the catalytic sites locate. Three of theβsubunits contain proteolyses sites, which are sequestered in the hollow interior of the 20S particle. Substrates enter the 20S through a narrow channel formed by theβsubunits, whose N-termini, depending on their conformation, can either obstruct or allow substrate entry and thus function as a gate. This entry channel is narrow and only permits passage of unfolded, linearized polypeptides.

哺乳动物26S蛋白酶体是由一个20S催化颗粒(catalytic particle，CP)和两个19S调节颗粒(regulatory particle，RP)组成的ATP(adenosine-triphosphate，ATP)依赖性蛋白水解酶复合体。20S CP是26S蛋白酶体的催化核心，它是由4个圆环堆叠形成的桶状复合物，其中两侧外环每个环是由α_1-α_7亚基组成，两个内环每个环是由β_1-β_7亚基组成，4个环的中央形成一个狭窄的内腔。2个β内环形成了20S CP的催化中心空腔，其内壁为催化活性位点所在地；外侧α环中心的孔道是底物到达催化中心空腔的通道，一般被α亚基上的N末端所封闭，阻止胞内非目的靶蛋白进入20S CP内被降解破坏。

A large lacuna occupies the center of many stems.

有些植物茎的中央有大型的空腔存在。2。

Mucor produced by formation of a domeshaped septum cutting off the sporangium from the sporangiohore.

在孢子囊的中央形成一个中空的腔，其外一层薄壁就叫做囊轴。

Here we present a case of 21 year-old male who suffered from recurrent swelling in left side of mandible which had received surgery for ossifying fibroma in another hospital when he was 19 years old. Obvious facial asymmetry was noted but no sensory dysfunctions were detected. The lesion showed well-demarcated, multilocular radiolucency but radiopacity centrally. We applied segmental resection via extra-oral approach and reconstructed with anterior iliac crest bone graft. After removal of MMF in six week, the wound healed well and joint function was good without malocclusion. After follow-up of one year, no recurrences were noted.

本病例为－21岁之男性，在19岁时因为左下颚骨角区肿大在某医院接受外科手术处理，术后病理报告为骨化纤维瘤，因为复发的肿胀而来本院寻求治疗，临床检查并无疼痛及下唇区感觉异常的问题，放射线影像为周界清晰，多腔室放射透过性合并中央放射不透过性之不规则小块，手术方式为从口外颚下切线，做下颚骨片段式切除，并以肠骨脊海绵骨移植修补骨缺损加以颚间固定六周，术后伤口恢复及愈合良好，颚骨关系稳定无咬合异常的情况，无张口受限的问题。

Abstract］ objective to improve the diagnosis of non-ossifying fiboma by analysing its x-ray feature.methods plain x-ray films was performed in all patients.x-ray finding in 8 cases with pathologically-confirmed non-ossifying were analyzed.results the clinical symptom was mild,the lesions occurred usually at the metaphysis of the long bones,the affected bones included femur（n=4）,tibia（n=3）,humerus（n=1）.cortical type was seen in 5 cases,presenting as unilocular or multilacular transparent areas with in the cortex or tightly beneath the cortex,the lesion had a sclerotic margin.which was more obvious at the marrow side.medullary type was seen in 2 cases.the lesion was located at the center of the bone and grew centrally.the tumor was manifested as unilocular or multilocular.tramsparent area with sclerotic border and the bone cortex became thinner with slightly expanding on 11 sides.conclusion plain radiography is the elementally means to detect this disease.based on the typical x-ray signs of non-ossifying fibroma combined with clinical data,correct preoperative diagnosis can be made in most cases.

目的 探讨非骨化性纤维瘤的x线表现以提高诊断水平。方法所有病例均摄有x线平片，分析经病理证实的8例非骨化性纤维瘤。结果临床症状轻，好发于下肢长骨干骺端或骨干，股骨4例，胫骨3例，肱骨1例。皮质型5例，表现为皮质内或紧贴皮质下的单层或多层透亮区，病变向骨内发展进入髓腔，周围有致密硬化带环绕，以髓腔侧明显；髓质型2例，病灶在骨内中央发展，显示为单房或多房透亮区，边缘有硬化，骨皮质菲薄，轻微向周围膨隆。结论 x线为最基本的检查方法，典型病例x线平片结合临床症状即可明确诊断。

The ventriculus terminalis is a small ependyma-lined cavity within the conus medullaris that is in direct continuity with the central canal of the anterior portion of the spinal cord.

终室是位于终室中并与终室其同轴的小的腔隙，它直接与脊索前部的中央管相连。

A central venous catheter was inserted for hemodynamic monitoring and blood transfusion. Cardiac tamponade occurred secondary to perforation of the superior vena cava by the central venous catheter. The patient's hemodynamic status became stable after pericardiocentesis. One week later she was discharged with no sequelae during the three month follow-up.

患者术后装置中央静脉导管以利於血行动力的评估及输血，病患进行中央静脉导管术时因上腔静脉穿刺破裂导致心包膜填塞及休克，经紧急照会心脏科医师后立即给予心包膜穿刺术，术后患者血压渐趋稳定情况好转於一星期后出院，经过三个月的追踪亦无后遗症。

Hepatic veno occlusive disease is caused by stenosis or obstruction of central vein and sublobular veins of hepatic lobules resulting in portal hypertension.

肝小静脉闭塞病是肝小叶中央静脉和小叶下静脉损伤导致管腔狭窄或闭塞而产生的门静脉高压症，临床表现类似于BCS，诊断依靠肝组织活检。

Results three different CT patterns were observed,a target lesion,a reniform mass,a sausage shaped mass,with a lower attenuation centrally,representing the intussuscepted mesentery.

结果 10 例CT扫描均可见多层靶环形、肾形或香肠形软组织影，中央部为脂肪和血管轴面影。2 例淋巴瘤多处可见肿大融合的淋巴结及肠壁不规则增厚，肠腔内造影剂充盈不均，1 例术中发现肠系膜过长而引起Tret's 韧带疝。

An oblique hole through the glass pipette holder (above the lateral hole for cell seal suction) is drilled, through which a microcatheter O.D.

利用通用的微电极夹持器在其抽吸负压的侧管上方钻一斜孔直通夹持器中央管腔。

I didn't watch TV last night, because it .

昨晚我没有看电视，因为电视机坏了。

Since this year, in a lot of villages of Beijing, TV of elevator liquid crystal was removed.

今年以来，在北京的很多小区里，电梯液晶电视被撤了下来。