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Proliferation of fibroblastic cells in bone marrow,caus in g anemia and sometimes enlargement of the spleen and liver.

骨髓纤维化,骨髓纤维变性在骨髓中成纤维细胞的扩散,常引起贫血症,而且有时也会导致脾和肝的增大

The bone marrow and spleen of the mice in both RT and HHE groups were examined at 1, 3, 5, 9 and 15 days after irradiation for bone marrow cellularity, DNA content in the bone marrow cells, and spleen/body weight ratio.

照后1、3、5、9、15d,分别取两组小鼠的骨髓和脾脏,获取骨髓有核细胞数、骨髓细胞DNA、脾/体质量比实验指标。

Anti-B220/anti-IgM antibodies were used to analyze number and maturation of central and peripheral B cells in transgenic mice. It is found that number of mature B cells decreased in bone marrow, spleen, peritoneal cavity. B cells in bone marrow of Tg mice were just one half of that of control, and in spleen, this number was even one third of that of the control.

以anti-B220/anti-IgM抗体分析了转基因小鼠中枢和外周B细胞数的变化及成熟情况,发现骨髓、脾和腹腔的成熟B细胞数都明显下降,其中骨髓和腹腔约为对照野生鼠的一半,而脾更低至三分之一。

Such massive splenomegaly is usually indicative of some myeloproliferative disease such as chronic myelogenous leukemia or myelofibrosis.

这样的脾肿大通常预示有骨髓增生型疾病,例如慢性髓性白血病或骨髓纤维化。

During human and fetal development, yolk sac, fetal liver, spleen and bone marrow give birth to blood cells in turn.

在胚胎与胎儿期,依次由卵黄囊、肝、脾、骨髓完成造血;出生后,骨髓成为主要的造血场所。

Subacut myeloid leukemia can be a defined type of leukemia. The common characteristics of subacute myeloid leukemia are as follows: the onset is insidious, and anemia and hemorrhage of skin and mucosa are the main clinical manifestations. Hepatosplenomegaly is rare. There are multilineage abnormalities in blood cell counts and increased blasts in the bone marrow with cytogenetical abnormal clone in most cases. The disease course is subacute and progressive.

1、亚急性髓性白血病是一个可以确定的白血病类型,其特征为:起病隐袭,以贫血或皮肤粘膜出血为主要症状,肝脾肿大的特征较少,血象为一系、二系或三系的异常,骨髓细胞形态学检查原早幼粒细胞异常增高,细胞遗传学检查多数有克隆性异常核型,病程中可有克隆演进,呈现亚急性而进行性的临床经过。

The ontogeny of hemopoietic and immune organs in the Chinese soft shelled turtl e, Trionyx sinensis , was studied and the morphological characteristics of tw o to three embryos from each embryonic stage described with histological examination .

采用常规孵化的中华鳖胚胎为材料,对不同发育时期造血和免疫器官进行了组织学研究,描述了卵黄囊、胸腺、肝、脾、肾以及骨髓的形态结构变化。

Meanwhile, in order to explore the stability of gene expression and the properties of gene-modified bone marrow cells further, we have observed the capability of reconstituting hematopoietic system of gene-modified and the expression of transduced gene in vivo by using of BMT to engraft lethally irradiated mouse with the gene-modified bone marrow cells.

同时,为进一步探讨转导细胞基因表达的稳定性以及生物学特征,本实验通过骨髓移植的方法,将基因标记骨髓细胞移植给受致死量照射小鼠,观察了基因转导细胞重建体内造血的能力,以及造血重建后外源基因在脾结节及骨髓细胞的表达。

The results presented in this paper indicated that sodium salt of 3,7-bishemis uccinate of 7-hydroxycholesterol (RS 634) at the dose of 45mg/kg/day (×7,ip) could increase DNA, RNA and protein syntheses in bone marrow cells and protein synthesis in liver,spleen and serum, but no markedly effects on DNA and RNA synthesis in liver and spleen of mice bearing EAC were observed, In the subacute test on rats RS 034 (400mg/kg/day, x30 ip) showed no evident effects on the number of RBC, WBC and the percentage of lym...

本文报告的结果表明7β-羟基胆固醇双琥珀酸单酯钠(RS 024)在有效抗肿瘤剂量下(45mg/kg/day,×7ip)对荷瘤小鼠骨髓细胞DNA、RNA和蛋白质合成有促进作用,对肝、脾的DNA、RNA合成无显著影响,但能促进肝,脾中及血清蛋白质合成。按400mg/kg/day连续给药30天,对大鼠红细胞、白细胞数及淋巴细胞百分率无明显影响。提示该药在有效抗癌剂量下毒性较小,并在一定程度上对免疫功能有增强作用。

In 3 of 14 mice surviving long-term transplanted with bone marrow cells transduced with high-titer virus, bone marrow, spleen and thymus from two mice and bone marrow and spleen from another mouse contained the intact proviral genome. Long-term expression of the transferred gene was seen in one mouse at level of 7%of endogenous murine α-globin gene.

5%。在2只长期造血重建小鼠的骨髓、脾、胸腺及另一只小鼠的骨髓及脾中整合有人β-珠蛋白基因,在一只重建小鼠的骨髓和脾中有人β-珠蛋白基因表达,约为鼠α-珠蛋白基因的7 %。

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As she looked at Warrington's manly face, and dark, melancholy eyes, she had settled in her mind that he must have been the victim of an unhappy attachment.

每逢看到沃林顿那刚毅的脸,那乌黑、忧郁的眼睛,她便会相信,他一定作过不幸的爱情的受害者。

Maybe they'll disappear into a pothole.

也许他们将在壶穴里消失

But because of its youthful corporate culture—most people are hustled out of the door in their mid-40s—it had no one to send.

但是因为该公司年轻的企业文化——大多数员工在40来岁的时候都被请出公司——一时间没有好的人选。