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This method holds promise for future clinical applications in therapy of hypersplenism.

HIFU消融脾脏治疗实验性脾肿大和脾亢是可行和有效的,该技术可以作为临床脾亢治疗的新尝试。

Female CB6F1 mice (F1 mice in short) which had been hypodermically inoculated with hepatoma cells (H22) were as recipients, and the C57BL/6 mice were as the donors. CB6F1 mice received intraperitoneal chemotherapy with cyclophosphamide. Fresh bone marrow and spleen cells from C57BL/6 mice were as donor cells, which were divided into with or without radiation of 60Co.

实验方法:以皮下接种肝癌细胞(H22)的CB6F1(BABL/C×C57BL/6杂交鼠,简称F1)雌性小鼠为受体鼠,经环磷酰胺腹腔化疗后,取C57BL/6小鼠的新鲜骨髓及脾脏细胞作为供体细胞,供体细胞分为经60Co照射和未经60Co照射。

In this study, oral tolerance was induced by tube-feeding transgenic mice with 0.5mg/day OVA protein daily, simultaneously sensitized by OVA protein with aluminum hydroxide. Oral-administered OVA protein (0.5mg/day for 5 or 10 consecutive days) resulted in significant lowered airway hypersensitivity as well as reduced inflammative cells infiltration, titer of serum OVA-specific IgE, IL-5 secretion in bronchoalveolar lavage fluid, and IL-4 secretion in splenocyte.

首先,本实验於小鼠中成功诱发了呼吸道过敏、大量OVA特异性IgE抗体生成、及嗜酸性白血球不正常聚集等现象;致敏前,同以连续管餵小鼠OVA抗原(0.5mg/day) 5天或10天后,结果显示皆能缓和呼吸道阻力、减低肺部发炎细胞浸润现象、降低血清中OVA特异性IgE抗体的生成量、也减少肺部冲洗液及脾脏细胞内第二型辅助T细胞(type II helper T cell, Th2)细胞激素的分泌(IL-4、IL-5)。

S patches and spleen of mice were studied with MTT assay. Results (1)Significant proliferation responses to intraoral immunization of CD4+T cells from the Peyer?

s patches与脾脏中的CD4+T细胞并以MTT法检测其对疫苗不同抗原成分的增殖反应。

Not only ALL clinical features, such as lymphadenectasis, splenomegaly, chest bone tenderness, higher proportion of immature lymphoblasts of bone marrow cells, but also typical clinical manifestations of HES, such as erythematous skin rash, thrombosis, endomyocardial fibrosis, were all observed.

除具有浅表淋巴结和脾脏肿大、胸骨压痛及骨髓原始幼稚淋巴细胞比例增高的ALL临床特点外,还具红斑性皮疹、血栓形成和心肌内膜纤维化典型HES的临床表现。

Methods 30 patients with trichloroethylene medicamentous dermatitis and 30 normal persons were selected as the observation group and the control group respectively; color Doppler was used to detect the spleen thickness and longitudinal length, spleen vein and artery diameters, the maximum blood velocity and blood flow of spleen vein and artery; RIA was applied to determine the serum levels of HA, LN, PCⅢ, CⅣ and CG; relevant analysis was made on the linear relationship between serum indices of hepatic fibrosis and spleen hemodynamics of the two groups.

选择30例三氯乙烯药疹样皮炎患者作为观察组,30例同时期健康体检者作为对照组,用彩色多普勒超声仪,检测脾脏厚度及长径、脾动静脉直径、脾动静脉血流量和脾静脉最大流速SPV(下标 x。用放射免疫法检测肝纤维化指标透明质酸、层粘连蛋白、Ⅲ型前胶原、Ⅳ型胶原和甘胆酸的水平,并对观察组与对照组的脾血流动力学参数与肝纤维化指标进行相关分析。

Results The Compound ShuangHuang liquor could increase the thymus index and the spleen index of the rats with severe degree burn. It could protect the function of excreting the SlgA in intestinal mucose, also.

结果 复方双黄溶液组大鼠的胸腺指数和脾脏指数、肠粘膜分泌SlgA的量明显高于烧伤对照组及烧伤胃饲大黄组,差异显著P<0.05。

With the loss of spleen function, antibody formation, opsonization and alternate complement production are all affected, producing an increased risk of infections, especially to encapsulated organisms (pneumococci, meningococci, salmonella).

随着脾脏功能、抗体形成、补体调理作用和交替产生作用的失去,机体感染几率增加,特别是对有夹膜的生物如肺炎球菌、脑膜炎球菌、沙门氏菌。

Methods Colony-forming unit of spleen, number of nucleated cells in bone marrow and spleen index were used to investigate the effect of polysaccharides at 50, 80 mg/kg from parmelia tinctorium intraperitoneal injection on hematopoietic function of mice irradiated with 137Cs γ-rays; DNA double-strand breaks were detected using alkaline single cell gel electrophoresis.

用内源性脾结节形成,骨髓有核细胞计数,脾脏指数观察石花多糖50,80 mg/kg腹腔注射对137 Csγ射线照射小鼠造血功能的影响;单细胞凝胶电泳技术检测小鼠淋巴细胞照射后的DNA双链断裂,观察给药后小鼠DNA损伤修复情况。

Another finding here is the irregular pale tan plaques of collagen over the purple capsule known as "sugar icing" or "hyaline perisplenitis" which follows the splenomegaly and/or multiple episodes of peritonitis that are a common accompaniment to cirrhosis of the liver.

此图的另一表现是紫色被膜上遍及胶原的异常淡褐色斑块,称为&糖衣&或&透明蛋白性脾周炎&,它继发于脾脏肿大和/或肝硬化常见并发症腹膜炎反复发作。

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