脾脏

Methods: Mice bearing in vivo transplanted tumor-H22 hepatic carcinoma were used to evaluate the drug"s activity of anti-tumor and GAPSGF"s efficacy enhancing effect by calculating the ratio of antitumor and q. HE dyeing was applied to observe the tumor"s morphological changes after the anti - tumor drug. It is observed the change of theperipheral white blood cells in serum and the body weight to analyze the GAPSGF"s toxicity reducing effect on the anti - tumor drug-Cytoxan. Applying ELISA method to observe the change of IL-2 in serum ,Applying carbon clearance method to test the function of uninuclear phagocyte,took the weight of the spleen and thoracic gland, analyzed the mechanism — efficacy enhancing and toxicity reducing of GAPSGF.

构建体内动物移植性H_(22)肝癌模型，通过计算抑瘤率与q值来分析药物的体内抗肿瘤活性，判断树舌多糖GF注射液的增效作用；采用瘤组织常规HE染色观察药物作用下的肿瘤细胞形态变化；观察外周血WBC数和体重改变来分析树舌多糖GF注射液对环磷酰胺抗肿瘤的减毒作用；采用ELISA法测定血清IL-2、小鼠碳粒廓清法测定单核吞噬细胞功能、取胸腺与脾脏称重测定脏器指数等以分析树舌多糖GF注射液增效减毒的作用机制。

Four different classⅡB alleles were observed in a single individual and two different 3'untranslated region

在鳗弧菌感染后的肝脏、脾脏、小肠和头肾组织中，卡方检验表明，MHCⅡB基因表现为具有极显著差异的表达(χ2=103.79，248.19，19.44和87.38，P.01)。

Alleviation or disappearance of preoperative esophagastric varix was observed in all patients.

此术式既能降压止血，又能减轻术后肝功能恶化，并保持脾脏的免疫功能。

Results 25 protuberances from outside organ (spleen, n=19; aorta, n=4; left hepatic lobe, n=1 and cyst of pancreatic tail, n=1) and 92 SMTs were detected by EUS including 63 myogenic ones (esophageal, n=34; gastric, n=29), 9 etopic pancreases in stomach, 8 esophgeal cysts, 3 varices in gastric fundus, 3 gastric lymphomas, 2 gastric lipomas, 2 Menetrier ' s disorders, 1 esophageal lipoma and varix each.

结果发现外压性改变25例（其中脾脏19例，主动脉弓4例，肝左叶、胰尾囊肿各1例）；粘膜下肿瘤92例，包括肌源性肿瘤63例（食管34例、胃29例），胃异位胰腺9例，食管囊肿8例，胃底静脉瘤3例，胃淋巴瘤3例，胃脂肪瘤2例，巨大胃粘膜肥厚症2例，食管脂肪瘤、食管静脉瘤各1例。

Methods The vasculature in the spleen specimens from 52 adult individuals was investigated with vascular casting.

方法以 5 2例成人新鲜脾脏为研究对象，采用血管铸型的方法。

And large numbers of mutant p53 protein were expressed in liver, kidney, ventriculus glandularis, tumor, oviduct. Moderate expression were detected in heart, pancreas, bone marrow, spleen, lung, duodenum, thymus and bursa of fabricius.

结果表明：突变型p53在肝脏、肾脏、腺胃、肿瘤、输卵管中表达量最高，心脏、胰脏、骨髓、脾脏、肺脏、十二指肠、胸腺及法氏囊均可检出中等量的表达。

Expression of mutant tumor suppressor gene p53 in egg-type chicken with avian leukosis subgroup J was detected to study cancericidally molecular mechanism of ALV-J. Using immunohistochemistry method of strep avidin-biotin complex, many organs of illed egg-type chickens, involved liver, kidney, ventriculus glandularis, tumor, heart, pancreas, bone marrow, spleen, oviduct, lung, duodenum, thymus and bursa of fabricius were studied.

为了探讨J亚群禽白血病病毒的致癌分子机理，观察蛋用型鸡发生J亚群禽白血病时p53抑癌基因在各脏器中的表达，应用链霉亲和素-生物素-过氧化物酶复合物免疫组化法，研究了蛋用型鸡J亚群禽白血病自然病例的肝脏、肾脏、腺胃、肿瘤、输卵管、心脏、胰脏、骨髓、脾脏、肺脏、十二指肠、胸腺和法氏囊。

Immunohistochemical method was used to detect avian leukosis virus subgroup J from egg-type chicken, which was preliminarily diagnosed to appear subgroup J avian leukosis. The organs from these chickens were examined by ALV-J gp85 monoclonal antibody, these organs included marrow, liver, spleen, kidney, lung, heart, pancreas, oviduct, ovary, ventriculus glanduaris, skeletal muscle, cerebrum, ischiacticus nerve.

采用免疫组化法，对病理学初步诊断为蛋用型鸡 J亚群白血病的自然发病鸡的肿瘤、骨髓、肝脏、脾脏、肾脏、肺脏、心脏、胰脏、输卵管、卵巢、腺胃、骨骼肌、大脑、坐骨神经，用特异性抗 J亚群禽白血病病毒囊膜糖蛋白gp85的单克隆抗体进行检测，待检的组织切片中均检出阳性抗原，免疫组化的研究结果与病理学诊断结果相一致。

This conclusion was further confirmed when effector CD8 T cells were generated in WT mice and adoptively transferred into WT or PFR second hosts on day 7 after infection.

我们还采用了另外一种方式来确认上述结果：在野生型小鼠中回输Thy-1.1~+OTI CD8T细胞并感染，7天后纯化脾脏Thy-1.1~+CD8T细胞，按相同细胞数分别回输到同步感染的野生型C57小鼠或PFR小鼠中，在PFR小鼠中同时回输经活化的野生型或者穿孔素缺陷的NK细胞。

Thy-1.1~+ OT-I CD8 T cells were adoptively transferred into Thy-1.2~+ host C57 mice treated with either isotype or PK136 Ab as mentioned above followed by injection i.v.withΔactA LM-OVA.On day 7 after infection,equal number of Thy-1.1~+ CD8 T effector cells from either hosts were sorted and adoptively transferred into second host mice(Thy-1.2) which were also on day 7 after infection and treated with isotype or PK136 Ab,respectively.

为进一步阐明NK细胞促进CD8Tm细胞的产生是作用于收缩期而不是扩增期，我们设计了如下的实验：将Thy-1.1~+ OT-I CD8 T细胞过继回输到经PK136抗体或对照抗体处理的C57小鼠体内并用ΔactA LM-OVA感染，7天后将两组小鼠脾脏中的Thy-1.1~+ CD8T细胞分离纯化后等量分别回输到同步感染的经PK136抗体或对照抗体处理的第二受体小鼠体内。

With Death guitarist Schuldiner adopting vocal duties, the band made a major impact on the scene.

随着死亡的吉他手Schuldiner接受主唱的职务，乐队在现实中树立了重要的影响。

But he could still end up breakfasting on Swiss-government issue muesli because all six are accused of nicking around 45 million pounds they should have paid to FIFA.

不过他最后仍有可能沦为瑞士政府&议事餐桌&上的一道早餐，因为这所有六个人都被指控把本应支付给国际足联的大约4500万英镑骗了个精光。