脾脏

There is close relation between BiP protein expression and increased functions of splenic macrophages induced by mild heat stress.

轻度热应激脾脏巨噬细胞BiP mRNA、BiP蛋白的表达与巨噬细胞功能发生同步改变，提示BiP蛋白表达上调可能与轻度热应激脾脏巨噬细胞功能增强密切相关。

After 10 days, 20 days and 30 days for grass carp (Ctenpharyngoden idellus Cuvier et Valencinnes) immunized by being injected Aeromonas hydrophilia, the ANAE (acid α-naphthyl acetate esterase) positive cells ratioes increased, and the same time it was found that the ACP activity increased up too, it showed that the fish bodies were being at immune responding situation and their immnue activities enhanced.

通过对草鱼免疫器官的六种同工酶的分析发现：LDH在血浆、血液细胞、脾脏和胸腺中都表达为5条区带，前肾还额外显示出X酶带，血浆只有3条酶带；ADH除了胸腺为一条带以外，其它的均为3条酶带；MDH和3-GPDH在这些组织中均表达为3条酶带；EST在前肾中为7条酶带，其余的都为6条酶带；POX只在前肾和脾脏中表达为2条酶带。

Thymus index, milt index and bursa of Fabricius index were measured and lymphocyte proliferation of peripheral blood and milt was detected.

试验期42 d。试验结束后，测定各组胸腺、脾脏和腔上囊系数及外周血和脾脏淋巴细胞的转化率。

The mice were killed after 10 days and the mice's body weight, spleen and thymus index, hemogram, myelogram, pathological changes of spleen,T lymphocyte subpopulation were detected.

给药10天后处死小鼠，检测小鼠体重、脾脏和胸腺指数、血像、骨髓像、脾脏病理和T淋巴细胞亚群等各项指标的改变。

Apoptosis of lymphocytes in bone marrow, spleen, thymus and bursa was detected by light microscope, electron microscope and terminal- deoxynucleotidyl transferase UIP nick end labeling. The results showed ALV-J could induce incoordinate apoptosis of lymphocytes in thymus, bursa and spleen, which was mainly found in early time. And the apoptosis was much more obvious in thymus than in other immune organs.

以电镜观察和HE染色、原位末端标记染色光镜观察对ALV-J感染和混合感染鸡的骨髓、脾脏、胸腺、法氏囊等免疫器官中淋巴细胞的凋亡进行了形态学研究，首次发现ALV-J可诱导胸腺、法氏囊和脾脏中不同程度的淋巴细胞凋亡，凋亡主要见于早期，ALV-J与REV混合感染时淋巴细胞凋亡尤为显著，以胸腺中最为明显。

We also have observed some organs pathological changes of juvenile Jian Carp, such as pancreas acinous gland and zymogen granules of acinous gland cell disappearing, intercellular substance hyperplasia and inflammatory cells soakage, hepatatrophia, liver cell granular or vacuolar degeneration and necrosis, karyolysis or pyknosis, glycogen granules decreasing, metanephros atrophy, metanephric canaliculus epithelium granular or vacuolar degeneration and necrosis, mitochondrion swelling and mitochondrion cristae disappearing, karyolysis, distal convolutal tubule microvilli desquamating, spleen marrow cell degeneration and necrosis, intercellular substance of spleen hyperplasia, spleen atresia, blood corpuscle disappearing.

后肾土黄色、淡褐色或苍白色，肾小管上皮细胞肿胀、颗粒或水泡变性、坏死，细胞内有大量血细胞流出，线粒体肿胀，嵴结构消失，细胞核溶解，肾间质甲状腺滤泡和拟淋巴细胞增生，远曲小管微绒毛脱落、管道细胞界限不清。心脏肌纤维肿胀、颗粒或空泡变性，严重的肌纤维溶解、变细或断裂，肌纤维间水肿、炎性细胞浸润，部分心肌细胞核浓缩。脾脏暗褐色，脾髓质细胞变性、坏死，拟淋巴细胞明显减少，淋巴细胞岛少见、岛中细胞成份减少，黑素巨噬细胞中心减少、体积缩小，脾脏网状基质水肿，脾窦闭锁，血细胞减少。

in order to probe into whether glycine supplementation plays an adjusting role in sports performance and immune functions, the authors divided 30 mice randomly into an exhaustive exercising group (e1), glycine supplemented exhaustive exercising group (e2) and a normal resting control group, with 10 mice in each group, supplemented glycine to mice in group e2 and physiological saline to mice in the other two groups, let mice in groups e1 and e2 do an exhaustive swimming exercise 4 weeks later, applied the trace ch50 hemolysis method to analyze supplement activity, applied the mtt method to perform a quantitative analysis on the lymphopoiesis ability of spleen, and thus revealed the following findings: compared with mice in group e1, the time taken by mice in group e2 to swim to an exhausted state is significantly longer (p.05); total supplement activity in blood serum of mice in group e1 is significantly lower than the same of mice in group s (p＜0.01), and total supplement activity in blood serum of mice in group e2 is significantly higher than the same of mice in group e1 (p.01), but still significantly lower than the same of mice in group s (p.05); as observed from the test of the lymphopoiesis ability of spleen, the lymphopoiesis ability of spleen of mice in group e1 is significantly lower than the same of mice in group s, and the lymphopoiesis ability of spleen of mice in group e2 is significantly higher than the same of mice in group e1, but still significantly lower than the same of mice in group s.

四型肽精氨酸脱氨酶在类风湿性关节炎。。。以马来酸酐与氨水为原料热缩聚法合成。。。摘要：为探讨甘氨酸补充对运动能力及免疫功能是否具有调节作用，将30只小鼠随机分成力竭游泳运动组(e1)、甘氨酸补充后力竭游泳组(e2)和静息正常对照组，每组10只。在e2组补充甘氨酸，其余两组给予生理盐水，处理4周后，e1组和e2组均做力竭性游泳运动。采用微量ch50溶血法分析补体活性，采用mtt法定量分析脾脏淋巴细胞增殖能力。结果显示，与e1组比较，e2组游泳至力竭的时间显著延长(p＜0.01)。e1组血清总补体活性显著低于s组(p＜0.01)，e2组显著高于e1组(p.01)，但仍显著低于s组(p.05)。在脾脏淋巴细胞增殖试验中观察到，e1组显著低于s组，e2组显著高于e1组但仍显著低于s组。

Objective To explore the diagnosis and therapy of primary malignant tumor of spleen.

目的 探讨脾脏原发性恶性肿瘤的诊断与治疗。方法回顾性分析4例脾脏原发性恶性肿瘤的临床资料。

The thymuses, spleens, sera and anticoagulant blood were collected after the rats were killed, to carry out these works:(1) Zinc concentrations were analyzed by atomic absorption spectrophotometry;(2) Body weight and the weight of thymuses and spleens were measured, the organ index were calculated;(3) Changes in pathology of thymus and spleen were observed;(4) Using TUNEL (terminal deoxynucleotidyl transferase-mediated dUTP nick end labeling) method, the apoptosis of thmocytes and spleen lymphocytes was checked;(5) The expression of bcl-2、bax mRNA in thymus and spleen were detected by RT-PCR (reverse transcription polymerase chain reaction);(6) The expression of p56〓, a signal transduction protein in thymus and spleen were detected by immunohistochemistry;(7) Two-color cytofluorometric analysis was used to assess the expression of CD4, CD8, CD45RA and CD45RC in peripheral blood lymphocytes.

动物处死后留组织、抗凝血及血清，进行以下检测：(1)原子吸收法测血清锌浓度；(2)测胸腺、脾脏脏器重量并与大鼠体重比较，计算脏器指数；(3)HE染色对胸腺、脾脏进行病理观察；(4)原位末端标记法测胸腺、脾脏中淋巴细胞的自发凋亡，并通过图像分析进行比较；(5)逆转录聚合酶链式反应检测凋亡调控基因bcl-2、bax mRNA在免疫器官中的表达；(6)免疫组化方法检测信号转导蛋白p56〓在免疫器官中的表达；(7)流式细胞术分析外周血淋巴细胞中CD4+、CD8+、CD45RA+及CD45RC+CD4+、CD45RC-CD4+细胞的数量和比例。

The results display that the thymus-index, spleen-nidex, immune globulins of IgA, IgG, IgM and alexins of C3, C4 in the experiment groups were significantly higher than those of the control group (P.05); the spleen's lymphocytes translation stimulate indexes in the experiment groups were higher than that of the control group at a significance level(P.01). The peritoneal macrophages can enhance the ability of swallowing. The ability of licking up neutral red was depended upon the dosage of drug.

与对照组相比，试验组的胸腺指数、脾脏指数、免疫球蛋白和补体C3、C4都升高且显著水平为差异显著(P.05)；脾脏淋巴细胞转移刺激指数均极显著地高于对照组(P.01)， 75μg/mL组的脾脏淋巴细胞转移刺激指数达最高；腹腔巨噬细胞具有一定的吞噬能力，吞噬中性红能力与剂量成依赖关系。

With Death guitarist Schuldiner adopting vocal duties, the band made a major impact on the scene.

随着死亡的吉他手Schuldiner接受主唱的职务，乐队在现实中树立了重要的影响。

But he could still end up breakfasting on Swiss-government issue muesli because all six are accused of nicking around 45 million pounds they should have paid to FIFA.

不过他最后仍有可能沦为瑞士政府&议事餐桌&上的一道早餐，因为这所有六个人都被指控把本应支付给国际足联的大约4500万英镑骗了个精光。