脾的

Objective To evaluate the feasibility and clinical results of retroperitoneal splenic autotransplantation in treatment of severe splenic injury.

目的 探讨自体腹膜后带蒂脾移植在严重脾外伤保脾手术中应用的可行性及价值。

This paper is mainly comprised of two components:preparation of models of rats suffering from deficiency of spleen Yang;comparison of the pharmacodynamics impacts of different Lizhong Pills formulations made up by dried ginger or its different components in Lizhong Pills to the different groups of the models.1 Establish the model of deficiency of spleen YANG induced by " cypsum fibrosum and anemarrhenae " with complex factors1.1 ObjectivesWith using heat-clearing and fire-purging drug cypsum fibrosum and anemarrhenae,insteading of the common usage of rhubarb and folium sennae,accompanied with irregular diet and overstrained,the model of deficiency of spleen-YANG is to be established,which is much close to the pathopoiesis theory of " frigidity and chilly damaging yang,irregular diet injuring qi,overstrain impairing the spleen" in TCM.1.2 MethodsModel rats is fully fed every other day,given the molding drug of cypsum fibrosum -anemarrhenae(concentration 4:1) with 3 different frequency,and arranged to swim everyday in 25℃water until exhausted(performing as spitting bubble 3 times continuously or sinking unable to float by itself).

全文共分为脾阳虚模型的制备和干姜及其成分对理中丸药效学影响的比较两大部分。1"石膏-知母"复合法脾阳虚模型的制备1.1目的以清热泻火药石膏-知母代替常用的大黄、番泻叶类苦寒泻下药，并结合饥饱失常、劳倦过度的方法进行造模，以期建立更符合中医"寒凉伤阳、饥饱伤气和劳倦伤脾"致病思路的中医脾阳虚证候模型。1.2方法模型动物隔日足量喂食，每日在25℃水中游泳，直至大鼠连续三次吐泡下沉，或沉入水底，3秒内不能自行浮出水面，并以三种不同给药频率灌胃给予石膏一知母煎液，比较石膏-知母不同给药方法对制备脾阳虚模型的影响。

Through measuring the pacients'ALT,AST,TBIL,vinus replication index,T lymPhoid cell,The NK cell, immunity globulin and complement etc in DH, LS, DH'two two treatments before and after, inquire and compare each immunity index sign and the relation of DH and LS;Observation DH two treatments in front and back each index sign and certificate integral calculuses change, comParing The treatment in front and back machine immunity function appearance.

分别检测湿热蕴脾证两组治疗前后和肝郁脾虚证组的ALT、AST、TBIL、病原学指标、肝脏B超以及血清T淋巴细胞、NK细胞、免疫球蛋白、补体的水平，观察、比较各免疫学指标与湿热蕴脾证、肝郁脾虚证的关系，观察湿热蕴脾证两组治疗前后各免疫学指标及中医证候积分的变化，比较治疗前后机体免疫功能的变化。

But only partial changes of rhubarb laxation group and over-swimming group have a coherent trend to those of SAS clinical patents. Our improved over-fatigue method is better than rhubarb laxation method and over-swimming method. Proved by Sijunzi decoction treatment, the mice behave normally. All objective indexes are improved more distinctively than the group that resumes naturally. These prove that the SAS model is made successfully and meets the requirements of judgement for SAS animal model. In this model, SAS is caused possibly by largely released Gas, which results in increased contractile in small intestine, over-exudation of intestine and obstacle in absorption.

在所选的指标中，改良型劳倦过度组小鼠的变化均与临床脾虚证患者的变化趋势一致，且多数指标的变化较大黄组(大黄泻下法塑造脾虚证动物模型)和力竭游泳组(力竭游泳法塑造脾虚证动物模型)明显，而大黄组和力竭游泳组只有部分指标的变化与临床患者一致，因此，改良型劳倦过度法塑造脾虚证动物模型优于大黄泻下法和力竭游泳法。

ASCL2 gene escapes genomic imprinting in skeletal muscle,fat, heart,liver,spleen,lung,kidney,stomach,small intestine,uterus,ovary and pituitary.(2) Both of the transcripts of NNAT gene is paternally expressed in skeletal muscle,fat,heart, liver,spleen,lung,kidney,stomach,small intestine,uterus,ovary and pituitary.(3) DIRAS3 gene is paternally expressed in skeletal muscle,fat,heart,liver,spleen,lung, kidney,stomach,small intestine,uterus,ovary and pituitary.(4) DLX5 gene is maternally expressed in skeletal muscle,fat,spleen,lung,stomach,small intestine,but escapes imprinting in heart,liver,kidney,uterus,ovary,testicle and pituitary.

1ASCL2基因在肌肉、脂肪、心、肝、脾、肺、肾、胃、小肠、子宫、卵巢和垂体中均逃脱印记；(2)NNAT基因两个转录本在肌肉、脂肪、心、肝、脾、肺、肾、胃、小肠、子宫、卵巢和垂体中均为母系印记：(3)DIRAS3基因在肌肉、脂肪、心、肝、脾、肺、肾、胃、小肠、子宫、卵巢和垂体中母系印记：(4)DLX5基因在骨骼肌、脂肪、肺、脾、胃和小肠中表达母本来源的等位基因，即表现为父系印记；而在心、肝、肾、子宫、卵巢、睾丸和垂体中表达双亲来源的等位基因，即逃脱印记。3。

Partial splenic arterial embolism were performed in 20 cases with cirrhosis of liver combined hypersplenia from 1998 to 2001, of them, male 12 cases, female 8cases.

为探讨部分脾动脉栓塞治疗脾功能亢进及食管静脉曲张的疗效，我们从 1998年- 2 0 0 1年对 2 0例肝硬化脾功能亢进患者进行部分脾动脉栓塞。

Methods 30 patients with trichloroethylene medicamentous dermatitis and 30 normal persons were selected as the observation group and the control group respectively; color Doppler was used to detect the spleen thickness and longitudinal length, spleen vein and artery diameters, the maximum blood velocity and blood flow of spleen vein and artery; RIA was applied to determine the serum levels of HA, LN, PCⅢ, CⅣ and CG; relevant analysis was made on the linear relationship between serum indices of hepatic fibrosis and spleen hemodynamics of the two groups.

选择30例三氯乙烯药疹样皮炎患者作为观察组，30例同时期健康体检者作为对照组，用彩色多普勒超声仪，检测脾脏厚度及长径、脾动静脉直径、脾动静脉血流量和脾静脉最大流速SPV(下标 x。用放射免疫法检测肝纤维化指标透明质酸、层粘连蛋白、Ⅲ型前胶原、Ⅳ型胶原和甘胆酸的水平，并对观察组与对照组的脾血流动力学参数与肝纤维化指标进行相关分析。

Results: After treatment, the histopathology and intestinal metaplasia subset of antral focal region, and the background lesion in ultrastructure of the mucosa in the nonfocal region were all improved in the 4 groups, The effects of Spleen-Qi Deficiency syndrome group and Spleen-Yang Deficiency group were superior to Ying-Deficiency group as well as Spleen-Deficiency and Qi-Stagnation group (P＜0.05, P＜0.01), and approached to those in the healthy control group.

结果：脾气虚证与脾阳虚证病理疗效优于脾阴虚证和脾虚气滞证(P＜0.05，P＜0.01)；4组脾虚证胃窦部病灶区组织病理、肠化生亚型和非病灶区粘膜超微结构中的&背景病变&，在治疗后均有改善，趋向接近于健康对照组。

This paper is mainly comprised of two components:preparation of models of rats suffering from deficiency of spleen Yang;comparison of the pharmacodynamics impacts of different Lizhong Pills formulations made up by dried ginger or its different components in Lizhong Pills to the different groups of the models.1 Establish the model of deficiency of spleen YANG induced by " cypsum fibrosum and anemarrhenae " with complex factors1.1 ObjectivesWith using heat-clearing and fire-purging drug cypsum fibrosum and anemarrhenae,insteading of the common usage of rhubarb and folium sennae,accompanied with irregular diet and overstrained,the model of deficiency of spleen-YANG is to be established,which is much close to the pathopoiesis theory of " frigidity and chilly damaging yang,irregular diet injuring qi,overstrain impairing the spleen" in TCM.1.2 MethodsModel rats is fully fed every other day,given the molding drug of cypsum fibrosum -anemarrhenae(concentration 4:1) with 3 different frequency,and arranged to swim everyday in 25℃water until exhausted(performing as spitting bubble 3 times continuously or sinking unable to float by itself).

全文共分为脾阳虚模型的制备和干姜及其成分对理中丸药效学影响的比较两大部分。1&石膏-知母&复合法脾阳虚模型的制备1.1目的以清热泻火药石膏-知母代替常用的大黄、番泻叶类苦寒泻下药，并结合饥饱失常、劳倦过度的方法进行造模，以期建立更符合中医&寒凉伤阳、饥饱伤气和劳倦伤脾&致病思路的中医脾阳虚证候模型。1.2方法模型动物隔日足量喂食，每日在25℃水中游泳，直至大鼠连续三次吐泡下沉，或沉入水底，3秒内不能自行浮出水面，并以三种不同给药频率灌胃给予石膏一知母煎液，比较石膏-知母不同给药方法对制备脾阳虚模型的影响。

Splenorrhaphy,partial and total splenectomy,transplatation of the splenic tissure in the omentum and packing or wraping spleen in pedicled omentum were used,according to splenic rupture grading and the principle of saving life first.

根据脾破裂的分级及抢救生命第一的原则，经脾修补、脾部分切除、脾切除术、脾组织大网膜内移植、带蒂大网膜填塞或包裹等治疗方法，治愈24例（85.7％），死亡4例（14.3％）。

As she looked at Warrington's manly face, and dark, melancholy eyes, she had settled in her mind that he must have been the victim of an unhappy attachment.

每逢看到沃林顿那刚毅的脸，那乌黑、忧郁的眼睛，她便会相信，他一定作过不幸的爱情的受害者。

Maybe they'll disappear into a pothole.

也许他们将在壶穴里消失