脾热

Generally, blood lipids are transformed by the essential substance from food. Exogenous pathogenic factors, food and spirit stimulation would make the spleen not to transport the body fluid orderly, then the fluid retention is gonging to convert into wetness-evil or chyle in the blood, what is the phlegm-wetness in the blood.

血脂在正常状态下是人体吸收了水谷精微所化生的精微物质，外感、饮食情志内伤等因素均可导致脾运障碍，脾不散精或脾不布津，津聚为湿，湿浊壅滞，反生浊脂，化为血中之痰浊，湿蕴从阳化热，酿生湿热，阻于中焦，蒙上流下，随之而来又渐渐影响到三焦所属脏腑的气化功能。

Methods:90 patients with HP associated antrum gastritis, duodenitis,antrum gastitis with duodenitis were divided into spleen deficiency group and damp heat in the spleen group.Each group has 45 patients.

对90 例HP感染的胃窦炎、十二指肠炎、胃窦炎并十二指肠炎患者进行中医辨证分型，即脾虚证与湿热蕴脾证各45 例，观察二证型对三联疗法根除HP效果的影响。

Through measuring the pacients'ALT,AST,TBIL,vinus replication index,T lymPhoid cell,The NK cell, immunity globulin and complement etc in DH, LS, DH'two two treatments before and after, inquire and compare each immunity index sign and the relation of DH and LS;Observation DH two treatments in front and back each index sign and certificate integral calculuses change, comParing The treatment in front and back machine immunity function appearance.

分别检测湿热蕴脾证两组治疗前后和肝郁脾虚证组的ALT、AST、TBIL、病原学指标、肝脏B超以及血清T淋巴细胞、NK细胞、免疫球蛋白、补体的水平，观察、比较各免疫学指标与湿热蕴脾证、肝郁脾虚证的关系，观察湿热蕴脾证两组治疗前后各免疫学指标及中医证候积分的变化，比较治疗前后机体免疫功能的变化。

The effects of Cortex phellodendri alkaloid on splenic lymphocyte proliferation after heat stress were detected by MTT chromatometry.On the basis of the above detection,CPAs extracted by limewater,ethanol,sulfuric acid water and the mixture of sulfuric acid-and-ethanol were choosen.

采用MTT法测定了热应激后小鼠脾淋巴细胞增殖的情况，以此作为醇提、碱提、酸醇提、酸提4种提取方法所得黄柏生物碱的筛选依据；采用ELISA法测定了醇提黄柏生物碱对热应激后小鼠脾淋巴细胞IFN-γ、IL-4分泌水平的动态影响。

She started to receive traditional Chinese medicine treatment on May 17 2008. Hodgkin's lymphoma falls into the area of scrofula, phlegm nodule, or tuberculosis of lymph node in TCM, and the mechanism is phlegm obstruction transforming into fire with stagnation of qi and blood, deficiency of liver and kidney and deficiency of both qi and yin.

本病是属於中医"痰核"、"瘰癧"、"恶核"等范畴，其病机为痰凝化火加上气血瘀结为患，就中医辨证分型而言，其病位在脾肝肾，病机在肝肾亏损、气阴两虚、痰凝兼有血瘀，并出现阴虚有热之证，秦艽鳖甲散可滋阴清热，软坚散结故作为本病主方，配合一贯煎来平补肝肾之阴，再以沙参麦冬汤来养阴生津清热。

This paper mainly aims at analysis of gastrointestinal mucosa gene expression profiles of paired samples about spleen deficiency of chronic superficial gastritis and normal people group, and spleen deficiency of chronic superficial gastritis and piwei damp-heat group. 9 and 12 different genes are selected by using Wilcoxon signed rank test, the ratio of quadratic sum between groups and within groups and distance-related analysis in the process of feature selection.

通过对慢性浅表性胃炎脾虚证与正常人、慢性浅表性胃炎脾虚证与脾胃湿热证两组胃肠粘膜配对样本的基因表达谱进行分析，在特征提取阶段分别利用Wilcoxon符号秩检验、组间和组内平方和比率、基于相关距离的冗余分析方法，分别得到9个和12个差异基因。

Nevertheless, According to Kaplan-Meier analysis, the 1-year graft survival rate was signicantly worse in the C4dgroup(62.9%) than in the C4dgroup (83.3%; log-rank P=0.038).(5) The distribution of deficiency syndrome as follows: spleen-kidney Qi deficiency (53.2%), hepatic and renal Yin deficiency (28.6%), spleen-kidney Yang Deficiency (18.2%). The distribution of sthenia syndrome as follows: syndrome of blood stasis(58.4%), damp-heat syndrome(20.8%), pathogenic damp(11.7%).

应用Kaplan-Meier法观察移植肾穿刺后的生存曲线，log-rank比较两组的移植肾生存率，P=0.040，两组穿刺后生存率差异具有统计学意义。6、观察77例慢性移植物肾病中虚证分布情况：脾肾气虚占53.2%，其次是肝肾阴虚占28.6%，脾肾阳虚占18.2%，而没有观察到阴阳两虚患者；实证分布情况：血瘀证占58.4%，其次是湿热证占20.8%，湿浊证占11.7%和水气证占7.8%，没有观察到风动证。

The mice inoculated with Coxiella burnetii intrana- sally developed interstitial pneumonia,while the primary pathological changes of mice inoculated intraperitoneally are granulomas in spleen and liver.2.The pathological changes became more severe followed the dosage increasing.3.Coxiella burnetii can be detected in spleen and liver at day 2 after inoculation.the lesion became more and more serious from day 2 to day 12.The characteristic changes were observed at day 7,and recovered at day 14. 4.The reticuloendothelial system are main target of Coxiella burnetii.The pathogen was detected in cytoplasm of monocyte -macrophages of spleen, liver, lung, and endothelioid cells of blood vessel. 5. Coxiella burnetii can be found in macrophages lysosomes by electron microscopy. Most of them are round or rod, and polymorphic shape can also be observed in different size.

结果：1、通过不同感染途径的实验证实，滴鼻感染的小鼠主要表现为间质性肺炎，而腹腔注射感染小鼠则以脾脏、肝脏肉芽肿为主要病变。2、通过不同剂量的感染实验发现，随着感染Q热立克次体剂量的加大，动物病变愈加严重。3、通过感染后不同时间的动态病理学观察发现，在腹腔注射后第2d的脾和肝脏即可发现病原体，主要脏器的病理变化从第2d到第12d逐渐加重，第7d动物的病变最典型，至感染后14d动物的受损器官已开始出现修复性变化。4、 Q热立克次体主要侵害机体的网状内皮系统，在感染小鼠的肝、脾、肺和外周血管单核巨噬细胞以及血管内皮细胞胞浆中查见病原体。5、透射电镜观察可见Q热立克次体主要位于巨噬细胞吞噬溶酶体内，呈多形性，多见圆形和杆状，大小不一。

Invigorating spleen and reducing fever is a kind of TCM therapeutic rue treated with Chronic colitis, Which is prescribed according to the theory of TCM and modern gastroenterological research combing with Professor Shan s clinical experience of more than forty years.

健脾清热法是单兆伟教授以中医脾胃理论及现代消化病学研究成果为依据，结合四十余年临床经验提出的治疗慢性结肠炎的方法。本文从理论和临床两个方面，对健脾清热法治疗慢性结肠炎作了较深入的探讨。

Objective: To observe the effect of chinese medicinal of fortify the spleen and resolve phlegm on serumal CRP and IL-6 of patients with type 2 diabetes melllitus of syndrome of dampness-heat encumbering the spleen.

目的：观察健脾化痰清热方药对湿热困脾证2型糖尿病患者血清C反应蛋白和白细胞介素6(IL-6)的水平变化。

She gently rebuff ed him, but agreed that they could be friends

她婉言拒绝了，但同意作为朋友相处。

If in the penal farm, you were sure to be criticized.

要是在劳改农场，你等着挨绳子吧！