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Results Multisystem were damaged,such as peripheral, hepatomegaly, splenomegaly,lymphadenectasis, endocrinopathy, skin changes, edema and plastcytosis in bone marrow are all more common damages, all of them peripheral neuropathy is the most characteristic manifestation.

结果本病是累及多系统的疾病,以周围神经病最具有特征性,肝、脾和淋巴结肿大,内分泌的病变,皮肤改变,水肿及骨髓浆细胞增多比较常见。

In the whole rats, the following tissues or organs were extracted and fixed in the most appropriated fixator (Bouin liquid or Formalin at 10%) then included in paraffin blocks : all the organs showing significant macroscopic lesions, encephalon (brain hemisphere, cerebellum and annular protuberance), spinal cord, sciatic nerve, salivary glands, esophagus, stomach, duodenum, jejunum, ileon, caecum and colon, rectum, liver, spleen, bone marrow, lymph node close to and at distance, thymus, heart, aorta, trachea, lungs, thyroid/parathyroid, surrenals, pancreas, hypophysis, kidney, bladder, gonad, uterus, mammary glands, epididymis, prostate, eyes, lachrymal glands, bones, skin, thigh muscle and implantation sites (2 per animal).

从整体大鼠内,下列组织或器官提取后用最适宜的固化剂( Bouin 液或10%的甲醛溶液)进行固定,然后包入石蜡块内:所有显示有明显肉眼可见损害的器官、脑髓、脊髓、坐骨神经、唾液腺、食道、胃、十二指肠、空肠、回肠、盲肠、大肠、直肠、肝脏、脾、骨髓、近端和远端淋巴结、胸腺、心脏、主动脉、气管、肺、甲状腺/甲状旁腺、肾上腺、胰腺、垂体、肾、膀胱、性腺、子宫、乳腺、附睾、前列腺、眼睛、泪腺、骨骼、皮肤、股肌以及假体植入部位(每只动物2处)。

Common clinical characteristics included marked neoplastic lymphocytosis, systemic lymphadenopathy, splenomegaly, and bone marrow involvement.

这5例共同的临床特征包括显著的肿瘤性淋巴细胞增生,系统性的淋巴结病、脾肿大及骨髓受累。

The laboratory findings of a typical CCML patient comprised of peripheral blood leukocytosis, basophilia and eosinophilia,myeloid differentiation in different stages, and increased megakaryocytes. The immunohistochemical features of the CCML consisted of highly positive MPO and CD68, significant lowering of neutrophil alkaline phosphatase, positive for Philadel- phia chromosome or chimeric BCR/ABL gene, etc. But in most cases of juvenile CCML, the Philadelphia chromosome could not be detected.

临床表现以乏力、低热、贫血、肝脾及淋巴结肿大为主要特点;典型儿童慢性髓细胞白血病的实验室特点有白细胞计数高、嗜酸和嗜碱性粒细胞增多、骨髓不同阶段髓细胞分化和巨核细胞增多;免疫组化提示CD68,髓过氧化物酶,中性粒细胞碱性磷酸酶积分明显减低,Ph染色体或BCR/ABL融合基因阳性,而幼年型CCML的Ph染色体常为阴性。

Caseous lymphadenitis in sheep and goat caused by Corynebaterium Pseudotuberlosis which could infect multiple animals, such as sheep, goat, camel, horse, bovine, is a kind of zoonotic and chronic infectious.

伪结核棒状杆菌能使绵羊、山羊、羊驼、骆驼、马、牛等多种动物致病,发病特征是受害动物的淋巴结肿大,呈脓性干酪性坏死;有的在肺、肝、脾和子宫角发生大小不等的结节,内含淡黄色干酪样物质。

Objective To study the mechanisms and expressions of Fas/FasL in the lungs,spleens and lymph nodes of SARS patients.

目的观察并探讨凋亡相关基因Fas/FasL在严重急性呼吸综合征病变组织肺、脾、淋巴结中的表达及其在SARS发病中的作用。

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