脱酰氨基

Then Doripenem came into the market in the July ,2005. We studied the synthesis of Doripemen.Firstly, we synthesized the chemical 2 from the starting material------o-hydroxylphenylacylamine through Reformastky reaction, alkylation, Diekmann reaction, enolization, esterification and etc. Secondly, we synthesized the chemical 3 from L — hydroxylproline through the protection of carboxyl, amidogen and hydroxyl group, reduction by NaBr, SN_2 substitution and Mitsumobu reaction.

我们以水杨酰胺为起始原料，经Reformatsky反应、烷基化、Diekmann环合、烯醇化、酯化等反应合成双环母核2；再从L-羟基脯氨酸出发，经酯化保护羧基、保护氨基、保护羟基、硼氢化还原酯得醇、Sn2取代和Mitsumobu反应等合成巯基侧链3；最后由化合物3经脱保护、水解得硫醇，和化合物2在二异丙基乙基胺的作用下缩合，最后Pd／C催化脱保护，历经16步反应最终得到产物多尼培南。

Chitosan is obtained by N-deacetylation of chitin. It has a number of free amino group.

壳多糖是甲壳质脱乙酰基的产物，它含有大量的自由氨基。

Insects polysaccharide from insect crust are a natural macromolecular polymers that remove behind the acetyl group getting usually that paries draw, which are currently found only bring positive charge of the animals cellulose in the natural world- containing amino polysaccharide of high-molecular compound.

昆虫多糖是从昆虫体壁提取的甲壳素脱去乙酰基后得到的一种天然高分子聚合物，也是目前发现的自然界中唯一带正电荷的可食性动物纤维素——含氨基多糖的高分子化合物。

In a system consisting of 20% PEG 400 and 12% magnesium sulfate, the partition coefficient of PGA was less than 0.01, PGA almost completely partitioned into the magnesium sulfate-rich bottom phase. Meanwhile, the partition coefficient of cephalexin was 6.7, the partition coefficients of phenylglycine methyl ester and 7-ADCA were 1.5 and 1.2, respectively.

通过考察头孢氨苄、苯甘氨酸甲酯和7-氨基脱乙酰氧基头孢烷酸(7-ADCA)在ATPS中的分配行为建立了一个含20%PEG 400和12%硫酸镁的ATPS，在此体系中头孢氨苄的分配系数为6.7，苯甘氨酸甲酯的分配系数为1.5，7-ADCA的分配系数为1.2，且青霉素酰化酶的分配系数小於0.01。

The target compound was synthesized from clarithromycin via hydrolyzation,acetylation,cyclic carbonatation,oxidation,decarbonatation,acylation,cyclic carbamatation and cyclization.

方法以克拉霉素为起始原料，经水解、乙酰化、环碳酸酯化、氧化、脱碳酸酯化、酰化、环氨基甲酸酯化和环合等反应合成目标化合物。

Several modified technology of food protein——acylation, phosphorylation, deamidation, glycosylation, cross linking, proteolysis were reviewed.

综述了酰化作用、磷酸化作用、脱氨基作用、糖基化作用、共价交联作用和蛋白水解作用等6种蛋白质改性技术及最新进展，认为用2种或2种以上方法先后对蛋白质改性是当今普遍使用的技术。

Methods: Serum alcohol and ALT、AST、GGT、ALP、CK、LDH、AMY、LIPA measured before and after beer consuming (4ml/kg) in 17volunteers. Meanwhile, the direct inhibitory effects of beer on the serum enzymes were studied by comparing the serum enzyme activities with or without beer.

利用17名健康志愿者，观察口服啤酒(4ml/kg)前后不同时间血液中酒精浓度及丙氨酸氨基转移酶、天冬氨酸氨基转移酶、γ-谷氨酰转肽酶、碱性磷酸酶、肌酸激酶、乳酸脱氢酶、淀粉酶、脂肪酶活性的变化，同时在体外加入血清中与体内浓度相近的啤酒，以观察啤酒对酶活性的直接影响。

Singing behavior; higher vocal center; caudal nucleus; ventral hyperstriatum; hippocampus; song-control nucleus; song nuclei; area X; melatonin; gamma-aminobutyric acid; glutamic acid decarboxylase; vocal control circuitry; frequency sensitivity; organ of Corti; auditory feedback; neural plasticity; seasonal plasticity; neostriatum; anterior forebrain pathway; lateral magnocellular nucleus; anterior neostriatum; lMAN nucleus; medial nucleus; dorsolateral thalamus; robustus archistriatalis; robust nucleus; archistriatum; song motor control nucleus; vocal motor system; gila cells; nonlinear oscillatory dynamics

歌唱行为；较高级的发声中枢；尾部核；腹侧上纹体；海马；鸣唱控制核团；鸣唱核；X区域；N-乙酰-5-甲氧基色胺；γ-氨基丁酸；谷氨酸脱羧酶；发声控制回路；频率灵敏度；柯替氏器；听觉反应；神经可塑性；季节可塑性；新纹状体；前脑前端路径；侧面大细胞核群；前部新纹状体；lMAN核；内侧核；背外侧丘脑；古纹状体粗核；健康的核；原纹状体；鸣声运动控制核；发声运动系统；毒蜥细胞；非线性振动动力学首页上一页共有 12 条记录，本页从第 11 到第 12 条。

It also widespread exists in the pericellular membrane of some fungus,insects,and algae,and in the cell walls of the advanced plant.The chitosan is the result of chitosan's dis-ethanoyl.

通过将甲壳素脱乙酰化可制得壳聚糖，壳聚糖是天然糖中唯一大量存在的碱性氨基多糖，其降解产物低分子量壳聚糖更是具有许多特殊的物理化学性质和生理功能。

From these experiments, the optinum condition was chosen. The comparison of the reactional results of different degree of deacetylation chitosan with those of N-substitute chitosan und...

在相同条件下，比较不同脱乙酰度甲壳胺及N－取代甲壳胺的接枝聚合反应结果，表明：甲壳胺中氨基参与了接枝聚合反应的引发过程。

The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应，而且减少跟风的可能性。