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脱辅基酶

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Holoenzyme A catalytically active complex made up of an apoenzyme and a coenzyme.

全酶:由一个脱辅基酶蛋白和辅酶组合而成的具有催化活性的复杂化合物。

The results showed that though apoHb could be reconstituted with all FePs, it showed different functions. Binding of apoHb with hemin can enhance the heterolytic cleavage of O-O bond of H〓O〓, but inhibiting the cleavage when FeTCPP and FeTPPS〓 were used instead of hemin. The binding of apoHb with FeTTMAPP showed negligible influence on the cleavage of O-O bond in H〓O〓.

结果表明,虽然具有阴离子基团的FeTCPP和FeTPPS〓能够在天然血红蛋白中辅基位置的附近与脱辅基血红蛋白结合,但是由于结构上与天然辅基的差别,使得血红素蛋白中相应的氨基酸残基不能起到有效的作用,因此不但不能提高反而抑制了其过氧化物酶活性;而对于具有阳离子基团的FeTTMAPP,脱辅基血红蛋白对其活性没有明显的影响。

In addition, SW480 and HCT116 cells were treated with deoxycholic acid for 15, 30, 45, 60, 90 and 120 minutes. It was found that the deoxycholic acid treated cells showed an elevation of ATP activity by 12.35 %, 20.08 %, 29.69 %, 33.56 %, 45.85 %, 54.32 %, respectively. While the HCT116 treated cells, showed an elevation of ATP activity by 3.69 %, 5.59 %, 8.52 %, 12.26 %, 16.52 %, 19.71%, respectively.From the experiments conducted using the cell lines described above, it was further confirmed that genes CYP7A1 (cytochrome P450, family 7, subfamily A, polypeptide 1), AKR1D1 (aldo-keto reductase family 1, member D1), ALDH1A1 (aldehyde dehydrogenase 1 family, member A1), BAAT (bile acid Coenzyme A: amino acid N-acyltransferase), ABCA1 (ATP-binding cassette, sub-family A, member 1), APOC3 (apolipoprotein C-III), LIPA, LIPE (lipase, hormone-sensitive), PTGER2 (prostaglandin E receptor 2) and PTGS2 (prostaglandin-endoperoxide synthase 2) were up-regulated.

此外,为了证实其脂肪代谢产物胆酸对细胞癌化的影响,亦使用SW480和HCT116细胞株,经由脱氧胆酸在15分钟、30分钟、45分钟、60分钟、90分钟和120分钟处理后,其细胞增生比率分别有12.35%,20.08%,29.69%,33.56%,45.85%和54.32%(p.05)以及3.69%,5.59%,8.52%,12.26%,16.52%和19.71%(p.05)上升情形,并从这些细胞株进一步证实CYP7A1(细胞色素P450-7A1)、AKR1D1(醇醛酮还原酶-1-D1)、ALDH1A1(醛脱氢酶-1-A1)、BAAT(胆酸辅酶A:氨基酸N-醯基转移酶)、ABCA1(三磷酸腺苷结合盒转运体A1)、APOC3、LIPA、LIPE(脂肪酶/激素敏感脂肪酶)、PTGER2(前列腺素E受体2)和PTGS2(前列腺素内过氧化物合成酶2)等基因表现皆有呈现向上调控的情形。

But,the natural pollen is what the person's stomach can't absorb and the natural nucleic acid also can't be absorbed as apoenzyme constituting the cell nucleus or mass.Therefore swallowing "natural pollen" is a kind of waste.

但是,天然花粉是人的胃不能吸收的,花粉中的天然核酸胃也是不能(如脱辅基酶,一种除去辅基的酶蛋白,或统称氨基酸一样地)被吸收的。

Apoenzyme An ENZYME whose cofactor or prosthetic group has been removed (e.g. via dialysis) rendering it catalytically inactive. It is the protein part of a conjugate enzyme.

脱辅基酶蛋白:酶的辅助因子或辅基去除后剩下的没有催化活性的部分,是共轭酶的蛋白质部分。

It was observed that not only histidine, but also histidine-Co and histidine-Ni could induce and substitute some Cu and Zn from Cu_2Zn_2SOD, eventually influence the activity of this metalloenzyme. Histidine- metal ion complexes have stronger ability than histidine to displace the bound metal ion from SOD. In addition, the amount of foreign metal ion binding to the SOD was less than that of metal ion lost from SOD. It obviously means that there was apoenzyme in the solution.

实验结果表明: Cu2Zn2SOD酶不仅与组氨酸,而且还可以与组氨酸-CoⅡ)和组氨酸-Ni(Ⅱ相互作用,Cu2Zn2SOD酶中的部分Cu和Zn被诱导和置换出来,并相应地影响了酶的活性;组氨酸-金属离子配合物的作用比组氨酸强,酶活性降低也更明显;酶中结合的外来金属离子的量比从酶上被诱导和顶替下来的金属离子的量要少,说明在溶液中有脱辅基酶的存在。

With the existence of additional carbon sources, sodium lactate, sodium propionate or sodium acetate, the faster pH rised, the faster p, p'-DDT dechlorinated, which indicate that the existence of short chain organic substrate supplies sufficient electron donors for the dechlorination process, and p, p'-DDT can obtain electrons more easily during the stage of pH rising.

并且由于p,p'-DDT的还原脱氯与细胞色素氧化酶及辅基FAD有关,外加碳源下p,p'-DDT的缺氧降解多数发生在体系pH值上升的阶段,且pH值上升较快时对应的p,p'-DDT缺氧降解较快,而在无外加碳源的体系中,由于可供p,p'-DDT还原脱氯的电子量限制了p,p'-DDT还原脱氯的速度,未发现上述现象。

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Plunder melds and run with this jewel!

掠夺melds和运行与此宝石!

My dream is to be a crazy growing tree and extend at the edge between the city and the forest.

此刻,也许正是在通往天国的路上,我体验着这白色的晕旋。

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单击"保存"会将文件保存到主持人的硬盘或服务器上,而不是您自己的计算机上。