脱细胞的

Objective To study the effects of different doses of manganese on activities of GS and PAG in the rat striatum and the activities of SDH and Na^＋-K^＋-ATPase in pallium in order to explore the cell molecular mechanism of manganese-induced exeitotoxicity.

目的研究不同剂量锰对大鼠纹状体谷氨酰胺合成酶、谷氨酰胺酶和脑皮质琥珀酸脱氢酶、钠钾三磷酸腺苷酶（Na^＋-K^＋-ATPase）活性的影响，以探讨锰的兴奋性毒性的细胞分子学机制。

Our results showed that LMWH at the concentrations of 16000and 8000 u·L(-1) could significantly (P.01, P.05 vs vehicle) inhibit constriction of isolated ileumsmooth muscle of ovalbumin-sensitized guinea pigs induced by OA in vitro, LMWH 200, 50and 12.5 u·kg(-1) ip could markedly (P.01 vs vehicle) inhibit degranulation of Pericranium MC inrats, LMWH 60 and 30 u·kg(-1) ip could significantly (P.01, P.05 vs vehicle) depress the lickingresponse induced by 4-aminopridine and the increasing of capillary permeability induced by aceticacid in mice.

研究结果显示，LMWH16000u·L(-1)（P＜0.01）和8000u·L(-1)（P＜0.05）均能显著降低OA所致的致敏豚鼠离体回肠平滑肌收缩高度；LMWH200u·kg(-1)，50u·kg(-1)和12.5u·kg(-1)（P＜0.01）均能明显抑制颅骨骨膜肥大细胞脱颗粒；LMWH60u·kg(-1)（P＜0.01）和30u·kg（P＜0.05）均能显著减少个氨基毗陡诱发的小鼠舔体反应次数，并能抑制冰乙酸所致的小鼠毛细血管通透性增加。

RESULTS:LMWH 16000 and 8000 u.L-1 could significantly inhibit the constriction of the isolated ileum smooth muscle of ovalbumin-sensitized guinea pigs induced by OA in vitro (P0.01,P0.05 vs vehicle);LMWH 200,50 and 12.5 u.kg-1ip could markedly inhibit the degranulation of pericranium MC in rats (P0.01 vs vehicle),LMWH 60 and 30 u.kg-1 ip could sigificantly depress the licking response induced by 4-aminopyridine and the increasing of capillary permeabili ty induced by acetic acid in mice (P0.01,P0.05 vs vehicle).

结果：LMWH 16000 u.L-1(P0.01)和8000 u.L -1(P0.05)均能显著降低OA所致的致敏豚鼠离体回肠平滑肌收缩高度；LMWH 200，50和12.5 u.kg-1 (P0.01)均能明显抑制颅骨骨膜肥大细胞脱颗粒；LMWH 60 u.kg-1(P0.01)和30 u.kg-1(P0.05)均能显著减少4-氨基吡啶诱发的小鼠舔体反应次数，并能抑制冰醋酸所致的小鼠毛细血管通透性增加。

"One of the difficulties — still — is in making the clinical decision of whether a child has type 1 or type 2 diabetes," Dr. Bennett explained. There are several characteristics that differentiate the two. Dr. Bennett reported that among the Pima, 92% of children with type 2 diabetes also had a family history of type 2 disease, most often in the mother. Other features include obesity (body mass index of 30 kg/m2 or greater),(68%), being asymptomatic (78%), and ketoacidosis (about 10%). These children and adolescents are not insulin-dependent and may stay that way for years, he said. They are also glutamic acid decarboxylase antibody– and islet cell antibody–negative.

Bennett博士解释道，在临床上决定孩童是第一型或是第二型糖尿病是有困难的，两者之间是有不同的特点，Bennett博士提到，在印地安人身上，92%的孩童发生第二型糖尿病是有家族史的，且与母亲有关，其他特徵还包括肥胖（身体质量指数大於等於30 kg/m2）占68%、无症状占78%、酮酸血症约占10%；Bennett博士指出，这些孩童与青少年并非胰岛素依赖型且持续好几年，他们在麸氨酸脱羧酶抗体与胰岛细胞抗体是呈阴性反应。

A single systemic injection of resiniferatoxin , an ultrapotent analog of capsaicin, produced a long-lasting, reversible blockade of adjuvant-induced thermal hyperalgesia and reduction of early edema in the adult rat. Depletion of mast cell granules in peripheral connective tissues with secretagogue compound 48/80 also reduced the hyperalgesia and early edema to some extent. Co-pretreatment with RTX and compound48/80 had the similar effects as that of RTX treated alone. After unilateral surgical sympathectomy, the thermal hyperalgasia and edema were both significantly enhanced.

成年鼠一次性注射辣椒素类似物resiniferatoxin后，长时程、可逆性阻断了CFA所致热痛过敏的发展并削弱了早期炎性水肿；用促脱颗粒剂compound48／80慢性耗竭外周结缔组织肥大细胞内分泌颗粒后，也部分削弱了热痛过敏及早期水肿的形成；RTX与compound48／80共同处理对热痛过敏及水肿有与RTX单独处理相近程度及时程的影响；单侧交感链切除显著易化了炎性热痛过敏及水肿。

BCR-ABL and mutant JAK2 inhibit the Bcl-x deamidation pathway and the apoptotic response to DNA damage in primary cells from patients with CML or polycythemia vera.

BCR-ABL和突变的JAK2可抑制CML或真性红细胞增多症患者Bcl -×的脱酰胺途径和原代细胞DNA损伤诱导的凋亡反应。

The ILDs related to smoking include respiratory bronchiolitis-associated interstitial lung disease, desquamative interstitial pneumonia, and pulmonary Langerhans cell histiocytosis.

目的：和吸烟有关的肺疾病从慢阻肺到肺癌是一组复杂原因的肺疾病，间质性肺炎只和吸烟有关，和吸烟有关的间质性肺炎包括：呼吸性细支气管炎、脱屑性间质性肺炎、肺的朗格汉斯细胞增多症。

Their dynamic morphological changes,growth curve,glycerophosphate dehydrogenase pattern,oil red O staining,and reaction to insulin and dexamethasone all verified their preadipocyte identity.

经形态学动态变化、生长曲线、甘油磷酸脱氢酶活性变化、油红O脂肪染色及对胰岛素和地塞米松反应的测定，证明是功能活跃的前脂肪细胞，并在体外重现了其增殖、肥大的全过程。

Amplified cells were cultured in PGC culture medium and non-adherence culture flask till idiosome formed, adhered and differentiated.

体外分化采用无黏附特性的培养瓶和除去白血病抑制因子的原始生殖细胞培养液，以脱饲养层法悬浮培养扩增的细胞，直到拟胚体形成及贴壁分化。

Objective In order to understand the role of the immune function in the pathogenetic mechanism of multiple sclerosis.

多发性硬化的病因尚不完全清楚，但其自身免疫的发病机制已得到证实和公认，属于特异性抗原介导的细胞免疫和体液免疫共同参与的中枢神经系统炎性脱髓鞘病。

We have no common name for a mime of Sophron or Xenarchus and a Socratic Conversation; and we should still be without one even if the imitation in the two instances were in trimeters or elegiacs or some other kind of verse--though it is the way with people to tack on 'poet' to the name of a metre, and talk of elegiac-poets and epic-poets, thinking that they call them poets not by reason of the imitative nature of their work, but indiscriminately by reason of the metre they write in.

索夫农 、森那库斯和苏格拉底式的对话采用的模仿没有一个公共的名称；三音步诗、挽歌体或其他类型的诗的模仿也没有——人们把&诗人&这一名词和格律名称结合到一起，称之为挽歌体诗人或者史诗诗人，他们被称为诗人，似乎只是因为遵守格律写作，而非他们作品的模仿本质。

The relationship between communicative competence and grammar teaching should be that of the ends and the means.

交际能力和语法的关系应该是目标与途径的关系。