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脱氧作用

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The specific inhibitor of DNA methylation that is available currently is 5-Aza-2'-deoxycytidine (5Aza-dc), which forms a covalent bond with the DNA methyltransferase, thus, limiting the number of free DMT molecules for methylating DNA and then decreasing its biology activity.

目前研究较多的甲基化抑制剂是胞苷类似物5-氮杂-2'-脱氧胞苷(5-Aza-2'-deoxycytidine, 5Aza-dc)。5Aza-dc的作用机制是与DNA甲基转移酶共价结合,降低酶的生物活性。

Reverse transcription polymerase chain reaction and western blot were used to detect the COCH and POU3F4/brn4 gene's expression. To investigate in vitro characteristics of COCH gene's expession, two factors were introduced in the culture medium of spiral ligament type Ⅰ fibrocytes respectively. Firstly, phosphorothionate-modified antisense oligodeoxynucleiotides to POU3F4/brn4 mRNA was applied to study the regulation effects of POU3F4/brn4 to COCH gene transcription.

引入人工合成的针对POU3F4/brn4基因mRNA的反义硫代磷酸寡聚脱氧核苷酸,干扰耳蜗螺旋韧带Ⅰ型成纤维细胞POU3F4/brn4的表达,免疫印迹检测反义干扰细胞POU3F4/brn4蛋白条带的强弱,RT-PCR检测反义寡核苷酸干扰细胞COCH基因转录水平的变化,观察POU3F4/brn4对COCH基因的转录调控作用。

The pathogen of gas gangrene mainly exist and live in local place, and seldom enter blood system to cause blood poisoning, but than can form lots of toxins, this toxins can harm blood system, kidney system, and also the tissue can putrescence and the wound will enlarge step by step, all tissue putrescence and toxin can make these bacteria easier to live and reproduce, all these situation if not being control in time will lead a serious situation that multiple organs dysfunction and then died

气性坏疽的病原菌主要在伤口内生长繁殖很少侵入血液循环引起败血症。产气夹膜杆菌产生α毒素、胶原酶透明质酸酶、溶纤维酶和脱氧核糖核酸酶等,红细胞破坏引起溶血血红蛋白尿、尿少、肾组织坏死水肿、液化,肌肉大片坏死使病变迅速扩散、恶化。糖类分解产生大量气体使组织膨胀;蛋白质的分解和明胶的液化,产生硫化氢,使伤口发生恶臭由于局部缺血,血浆渗出,及各种毒素的作用伤口内的组织和肌肉,进一步坏死和腐化,更利于细菌的繁殖使病变更为恶化。

Head blight not only causes the severe grain yield loss, but also causes the harvested grain contaminated with several mycotoxins, such as deoxynivalenol and zearalenone. The consumption of food product made from grains contaminated with these toxins is a potential problem for human and farm animals, which is known to cause carcinogenic, genotoxic acute or chronic diseases or to directly target the kidney, liver or immune system, and has caused great concern of food safety.

赤霉菌引起小麦的穗腐,不仅使小麦籽粒产量降低、品质变劣,而且病麦粒中存留有病菌产生的真菌毒素,如脱氧雪腐镰刀菌烯醇(Deoxynivalenol,DON)和玉米赤霉烯酮(Zearalenone,ZEN),食用污染毒素的病麦及其制成品后会引起人畜中毒,还有致癌、致畸和诱变的作用。

What is the function of ligase in DNA replication?

什麽是连接酶的作用在脱氧核糖核酸复制的?

This study was to observe the inhibitory effect of 5-Aza-CdR on the growth of human nasopharyngeal carcinoma cells and xenografts in nude mice, explore the possible mechanisms, and search for new treatment target of NPC.

本文观察了5-杂氮-2'-脱氧胞苷对人鼻咽癌细胞及其裸鼠移植瘤的抑制作用,探讨其抗肿瘤效应及可能的机理,寻找鼻咽癌治疗的新靶点。

Of or relating to bile, the bile ducts, or the gallbladder.Either of two bodily humors, black bile or yellow bile, in medieval physiology.

进行7-α脱羟作用生成的胆汁酸,称为次级胆汁酸,包括脱氧胆酸和石胆酸。。。。

Bcl-2 mRNA was detected by RT-PCR in all cells;(2)After normal rat and bile duct-ligated 14d rat hepatocytes were added 100 μmol/L GCDC and kept for 24 hours, cells were evaluated by FCM and TUNEL. Results:(1)Normal rat hepatocytes did not express Bcl-2 by RT-PCR technique. Bcl-2 was expressed in 7-,14-,21- day BDL rats.

分离对照组及实验组14 d组大鼠的肝细胞行原代培养后,使用100 μmol/L甘氨鹅脱氧胆酸钠作用于两组肝细胞24 h后,用FCM法测定肝细胞的凋亡比率,用TUNEL技术进行肝细胞凋亡的原位检测。

Objective: The aim of this study was to investigate the effects of ginsenoside Rg3 and ginsenoside Rg3 combined with cisplatinon the growth of nude mice cervical cancer, and to explore the possible mechanism of ginsenoside Rg3 and ginsenoside Rg3 combined with cisplatinin cells and molecules levels. The growth of human cervical cancer Hela cell, apoptosis of tumor cells , expression of CD31and PeNt were observed with optic microscope, radio-immunity immunological histo chemistry, terminal deoxynucleotidy transferase-mediated dUTP nick end labeling, and immunohistochemical staining. The purpose of this study is to provide a new way of medication to eure cervical cancer in clinic.

目的:本实验通过建立子宫颈癌裸鼠病理模型后,以此为研究对象,运用光镜、免疫组化及末端脱氧核苷酸转移酶介导的dUTP缺口末端标记技术,观察人参皂甙Rg3[20—Ginsenoside Rg3]和顺铂单独及二者联合应用对人宫颈癌Hela细胞裸鼠移植瘤生长的影响,重点研究肿瘤的生长、肿瘤细胞的凋亡及PCNA、CD31的表达情况,以期从细胞及分子水平揭示人参皂甙Rg3和顺铂单独及二者联合应用对人宫颈癌Hela细胞的作用机制,为临床上药物治疗与预防宫颈癌寻找更加完善的途径。

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According to the clear water experiment, aeration performance of the new equipment is good with high total oxygen transfer coefficient and oxygen utilization ratio.

曝气设备的动力效率在叶轮转速为120rpm~150rpm时取得最大值,此时氧利用率和充氧能力也具有较高值。

The environmental stability of that world - including its crushing pressures and icy darkness - means that some of its most famous inhabitants have survived for eons as evolutionary throwbacks, their bodies undergoing little change.

稳定的海底环境─包括能把人压扁的压力和冰冷的黑暗─意谓海底某些最知名的栖居生物已以演化返祖的样态活了万世,形体几无变化。

When I was in school, the rabbi explained everythingin the Bible two different ways.

当我上学的时候,老师解释《圣经》用两种不同的方法。