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Exotoxin A of Pseudomonas aeruginosa can injury keratocytes and its effect is in a dose-dependent manner.

绿脓杆菌外毒素A,破坏角膜基质细胞,对兔角膜基质细胞毒性作用有剂量依赖性。

Methods Three-dimensional gels of type I collagen containing rabbit keratocytes were incubated in the presence of different concentrations of exotoxin A (0.1,1.0,10 mg·L-1),cultivated for 24 h at 37℃, the change of keratocytes in morphology was observed under the light microscope,and the amount of lactate dehydrogenase was measured by enzyme linked immunosorbent assay.

含兔角膜基质细胞(1×105·mL-1)三维胶原凝胶表面添加提纯的不同浓度绿脓杆菌外毒素A(0.1、1.0和10 mg·L-1)后,放入无血清MEM培养液中37℃培养24 h,采用光学显微镜观察培养的兔角膜基质细胞形态学变化,采用酶联免疫吸附法检测损伤的兔角膜基质细胞释放的乳酸脱氢酶含量。

RESULTS We successfully obtained human caspase-3 gene, the genes and expression vectors of reversed caspase-3 and its fusion protein with part of the translocation domain of Pseudomonas exotoxin A. Compared with the control group, the expression of both genes caused in a similar degree the decrease of living cell numbers and massive occurrence of apoptosis.

结果成功获得了caspase-3基因,构建了重构型caspase-3基因和重构型caspase-3与绿脓杆菌外毒素转膜结构域部分肽段的融合蛋白基因及其表达载体,与对照组相比,在转染后1~4 d内,两种基因的表达均导致HeLa细胞存活数减少,大量细胞发生凋亡,且二者活性相当。

Results:It was found that in experimental group,retinal neurofibril were disorder,the ganglion cell,the cells in inner and outer nuclear layer presented nibble like lysis,necrosis and lose.gradually at 1,3,5 day after moc...

结果:接种后1、3、5天,对照组未见异常改变,绿脓杆菌接种组视网膜神经纤维排列紊乱、消失,神经节细胞、内核层细胞及外核层细胞从内向外呈蚕蚀样溶解或坏死脱落。

Discussion TNF-αis an inflammatory cell cytokine,with the properties of autocrine, produced by cadiocyte at the early age of MIRI,inducing myocardial function abnormal and cadiocyte necrosis in MIRI、pyaemia、chronic cardiac insufficiency、viral myocarditis and the homograft rejection of heart.

讨论 TNF-α是心肌缺血再灌注早期心肌细胞产生的炎性细胞因子,是一种自分泌的作用因子,在缺血再灌注损伤、脓毒症、慢性心功能不全、病毒性心肌炎以及心脏同种移植排斥反应中均能导致心肌功能能障碍和心肌细胞坏死。

Objective To investigate the relationship between changes in renal cell apoptosis and inflammatory cytokines in sepsis rats.

目的 研究脓毒症时肾脏组织细胞凋亡变化与炎症细胞因子的关系。

Liver sinusoidal endothelial cell is an important source of cytokine production in mice with sepsis.

肝窦内皮细胞是脓毒症时肝组织中细胞因子的重要来源之一。

During the surgery, the lesion was found to be a solid tumor. A surgical wedge biopsy was done and purulent dark yellow fluid was drained from the center of the mass. Histologically, there was a solid pattern of rhabdoid and anaplastic round or oval cells haphazardly arranged with poor differentiation. Immunohistochemical staining was positive for vimentin, a mesenchymal marker; the reticulin staining was consistent with carcinoma.

我们实施了手术切片及肿瘤中心脓状物引流,病理组织学上,我们发现了不规则或未分化的横纹状、圆形及椭圆形细胞;免疫组织染色上,细胞广泛的对非上皮标记vimentin呈阳性反应、且其reticulin染色呈现出腺癌的形式;肉瘤及腺癌的特色皆可在切片中看到,所以我们的诊断是类肉瘤性线癌。

PTX at tenuates the ALI induced by LPS or sepsis in rat. The therapeutic effects of PTX include:improve oxygenation, at tenuate pulmonary edema formation, enhance animal survival in sepsis-induced ALI. The mechanisms may related with the effects of PTX inhibiting the chemotaxis, migration, activation of inflammatory leukocytes, diminishing the production of active oxygen, and inhibiting inflammatory cytokine release partly.

4PTX对大鼠内毒素性ALI及脓毒症性ALI均有一定的防治作用,主要表现在改善动脉血氧合,减轻肺水肿形成,提高脓毒症性ALI大鼠的存活率等方面,其机理可能与抑制白细胞趋化与激活,减少肺内白细胞渗出及活性氧产生,一定程度上抑制炎性细胞因子生成等有关。

A generally viscous, yellowish-white fluid formed in infected tissue, consisting of white blood cells, cellular debris, and necrotic tissue.

脓,脓液通常是粘性的,黄白色的,由受感染的肌体组织形成的液体,由白血球,细胞碎片和坏死的组织

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推荐网络例句

I am accused of being overreligious," she said in her quiet, frank manner,"but that does not prevent me thinking the children very cruel who obstinately commit such suicide.""

客人们在卡罗利娜·埃凯家里,举止就文雅一些,因为卡罗利娜的母亲治家很严厉。

Designed by French fashion house Herm è s, this elegant uniform was manufactured in our home, Hong Kong, and was the first without a hat.

由著名品牌 Herm è s 设计,这件高贵的制服是香港本土制造,是我们第一套不配帽子的制服。

Do not 'inflate' your achievements and/or qualifications or skills .

不要 '夸大' 你的业绩或成果,条件或者技能。